COAD 4-phosphopantetheine adenylyltransferase [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: COAD
Official Full Name: 4-phosphopantetheine adenylyltransferase
Primary source: TAIR:AT2G18250
Locus tag: AT2G18250
See related: Araport:AT2G18250
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: 4-phosphopantetheine adenylyltransferase; ATCOAD; T30D6.24; T30D6_24
Summary: At2g18250 encodes pantetheine-phosphate adenylyltransferase catalyzing the formation of dephospho-CoA from pantetheine 4'-phosphate. The enzyme is involved in coenzyme A biosynthesis.
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Chromosome 2 - NC_003071.7 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

catalyzes a regulatory step in the CoA biosynthetic pathway that plays a key role for plant growth, stress resistance, and seed lipid storage
Title: The coenzyme a biosynthetic enzyme phosphopantetheine adenylyltransferase plays a crucial role in plant growth, salt/osmotic stress resistance, and seed lipid storage.

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NM_127383.3

Function	Evidence Code	Pubs
enables pantetheine-phosphate adenylyltransferase activity	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within coenzyme A biosynthetic process	IDA Inferred from Direct Assay more info	PubMed
involved_in coenzyme A biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within lipid metabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within lipid storage	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of coenzyme A biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to osmotic stress	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to salt stress	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	ISM Inferred from Sequence Model more info

NP_179417.1

4-phosphopantetheine adenylyltransferase (COAD); CONTAINS InterPro DOMAIN/s: Rossmann-like alpha/beta/alpha sandwich fold (InterPro:IPR014729), Cytidyltransferase-related (InterPro:IPR004821), Cytidylyltransferase (InterPro:IPR004820); Has 633 Blast hits to 630 proteins in 285 species: Archae - 179; Bacteria - 4; Metazoa - 125; Fungi - 130; Plants - 59; Viruses - 0; Other Eukaryotes - 136 (source: NCBI BLink).

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The following sections contain reference sequences that belong to a specific genome build. Explain