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    RIBA2 riboflavin biosynthesis protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816777, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RIBA2
    Official Full Name
    riboflavin biosynthesis protein
    Primary source
    TAIR:AT2G22450
    Locus tag
    AT2G22450
    See related
    Araport:AT2G22450
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtRIBA2; F14M13.15; F14M13_15; homolog of ribA 2
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    Genomic context

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    See RIBA2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    7
    Sequence:
    Chromosome: 2; NC_003071.7 (9530365..9533066)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene homeobox protein 6 Neighboring gene non-LTR retroelement reverse transcriptase Neighboring gene MIZU-KUSSEI-like protein (Protein of unknown function, DUF617) Neighboring gene uncharacterized protein Neighboring gene arabinogalactan protein 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis RIBA proteins: two out of three isoforms have lost their bifunctional activity in riboflavin biosynthesis. Hiltunen HM, et al. Int J Mol Sci, 2012 Oct 31. PMID 23203051, Free PMC Article
    2. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article
    3. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    NM_127810.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 3,4-dihydroxy-2-butanone-4-phosphate synthase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    NOT enables GTP cyclohydrolase II activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in riboflavin biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    riboflavin biosynthesis protein
    NP_179831.2
    • riboflavin biosynthesis protein, putative; FUNCTIONS IN: 3,4-dihydroxy-2-butanone-4-phosphate synthase activity, GTP cyclohydrolase II activity; INVOLVED IN: riboflavin biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: GTP cyclohydrolase II (InterPro:IPR000926), Riboflavin biosynthesis protein RibA (InterPro:IPR016299), DHBP synthase RibB (InterPro:IPR000422), DHBP synthase RibB-like alpha/beta domain (InterPro:IPR017945); BEST Arabidopsis thaliana protein match is: GTP cyclohydrolase II (TAIR:AT5G64300.1); Has 11284 Blast hits to 11282 proteins in 2317 species: Archae - 207; Bacteria - 6851; Metazoa - 1; Fungi - 301; Plants - 119; Viruses - 0; Other Eukaryotes - 3805 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      9530365..9533066
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127810.4 → NP_179831.2  riboflavin biosynthesis protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_179831.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q6NLQ7, Q9SJY9
      UniProtKB/TrEMBL
      A0A5S9X0F7, A0A654F074, A0A7G2EE69
      Conserved Domains (1) summary
      PLN02831
      Location:71 → 474
      PLN02831; Bifunctional GTP cyclohydrolase II/ 3,4-dihydroxy-2-butanone-4-phosphate synthase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6NLQ7.1

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