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    PAB5 poly(A)-binding protein 5 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843507, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PAB5
    Official Full Name
    poly(A)-binding protein 5
    Primary source
    TAIR:AT1G71770
    Locus tag
    AT1G71770
    See related
    Araport:AT1G71770
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F14O23.15; F14O23_15; POLY(A)-BINDING PROTEIN; poly(A)-binding protein 5
    Summary
    Encodes a Class I polyA-binding protein. Expressed in floral organs. Binds polyA sepharose in vitro.
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    Genomic context

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    See PAB5 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    8
    Sequence:
    Chromosome: 1; NC_003070.9 (26990525..26994259, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene nucleolar protein Neighboring gene Hypoxanthine-guanine phosphoribosyltransferase Neighboring gene uncharacterized protein Neighboring gene WD repeat protein Neighboring gene Subunits of heterodimeric actin filament capping protein Capz superfamily

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional analysis of the Arabidopsis thaliana poly(A) binding protein PAB5 gene promoter in Nicotiana tabacum. Luo K, et al. Plant Cell Rep, 2008 Dec. PMID 18779966
    2. A pollen-, ovule-, and early embryo-specific poly(A) binding protein from Arabidopsis complements essential functions in yeast. Belostotsky DA, et al. Plant Cell, 1996 Aug. PMID 8776896, Free PMC Article
    3. Differential organ-specific expression of three poly(A)-binding-protein genes from Arabidopsis thaliana. Belostotsky DA, et al. Proc Natl Acad Sci U S A, 1993 Jul 15. PMID 8341686, Free PMC Article
    4. Four distinct classes of proteins as interaction partners of the PABC domain of Arabidopsis thaliana Poly(A)-binding proteins. Bravo J, et al. Mol Genet Genomics, 2005 Feb. PMID 15650869
    5. Identification of ubiquitinated proteins in Arabidopsis. Manzano C, et al. Plant Mol Biol, 2008 Sep. PMID 18535787

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. the promoter region between -1,653 and -1,014 was necessary to direct the tissue-specific expression of PAB5 promoter during development
      Title: Functional analysis of the Arabidopsis thaliana poly(A) binding protein PAB5 gene promoter in Nicotiana tabacum.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001198444.1
    NM_105835.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables poly(A) binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables translation initiation factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within nuclear-transcribed mRNA poly(A) tail shortening IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within translational initiation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol HDA PubMed 
    located_in mitochondrion HDA PubMed 

    General protein information

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    Preferred Names
    poly(A)-binding protein 5
    NP_001185373.1
    • poly(A)-binding protein 5 (PAB5); CONTAINS InterPro DOMAIN/s: Polyadenylate-binding protein/Hyperplastic disc protein (InterPro:IPR002004), RNA recognition motif, RNP-1 (InterPro:IPR000504), Polyadenylate binding protein, human types 1, 2, 3, 4 (InterPro:IPR006515), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677), RNA recognition, domain 1 (InterPro:IPR003954); BEST Arabidopsis thaliana protein match is: poly(A) binding protein 3 (TAIR:AT1G22760.1).
    NP_177322.2
    • poly(A)-binding protein 5 (PAB5); FUNCTIONS IN: RNA binding, poly(A) RNA binding, translation initiation factor activity; INVOLVED IN: translational initiation, nuclear-transcribed mRNA poly(A) tail shortening; LOCATED IN: cytosol, nucleus; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Polyadenylate-binding protein/Hyperplastic disc protein (InterPro:IPR002004), RNA recognition motif, RNP-1 (InterPro:IPR000504), Polyadenylate binding protein, human types 1, 2, 3, 4 (InterPro:IPR006515), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677), RNA recognition, domain 1 (InterPro:IPR003954); BEST Arabidopsis thaliana protein match is: poly(A) binding protein 3 (TAIR:AT1G22760.1); Has 55698 Blast hits to 24293 proteins in 890 species: Archae - 24; Bacteria - 3417; Metazoa - 28886; Fungi - 7111; Plants - 10105; Viruses - 0; Other Eukaryotes - 6155 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      26990525..26994259 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001198444.1 → NP_001185373.1  poly(A)-binding protein 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001185373.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q05196, Q9M9G9
      UniProtKB/TrEMBL
      A0A178WJE2, A0A5S9WRW7, A0A654EN43
      Conserved Domains (1) summary
      TIGR01628
      Location:59 → 661
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family

    2. NM_105835.2 → NP_177322.2  poly(A)-binding protein 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_177322.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q05196, Q9M9G9
      UniProtKB/TrEMBL
      A0A178WJE2, A0A5S9WRW7, A0A654EN43
      Conserved Domains (1) summary
      TIGR01628
      Location:59 → 661
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q05196.3

    Gene LinkOut

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