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    PAS domain-containing protein tyrosine kinase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843117, updated on 18-Sep-2024

    Summary

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    Official Full Name
    PAS domain-containing protein tyrosine kinase family protein
    Primary source
    TAIR:AT1G67890
    Locus tag
    AT1G67890
    See related
    Araport:AT1G67890
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    RAF11; T23K23.26; T23K23_26
    Summary
    Encodes a protein with similarity to RAF MAP kinases. Based on loss of function phenotype, RAF11 appears to be involved in mediating ABA responses such as dormancy and environmental stress. Expressed in most plant tissues but excluded from root tips and young leaves.
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    12
    Sequence:
    Chromosome: 1; NC_003070.9 (25457033..25462847)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene glycine-rich protein Neighboring gene beta-1,4-N-acetylglucosaminyltransferase family protein Neighboring gene Phototropic-responsive NPH3 family protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis putative MAP kinase kinase kinases Raf10 and Raf11 are positive regulators of seed dormancy and ABA response. Lee SJ, et al. Plant Cell Physiol, 2015 Jan. PMID 25324504
    2. Genome-wide analysis and experimentation of plant serine/ threonine/tyrosine-specific protein kinases. Rudrabhatla P, et al. Plant Mol Biol, 2006 Jan. PMID 16429265
    3. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385
    4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001084319.2
    NM_001334334.1
    NM_001334335.1
    NM_105459.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine/tyrosine kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within maintenance of seed dormancy IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of abscisic acid-activated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to glucose IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    PAS domain-containing protein tyrosine kinase family protein
    NP_001077788.1
    • PAS domain-containing protein tyrosine kinase family protein; FUNCTIONS IN: protein serine/threonine/tyrosine kinase activity, kinase activity; INVOLVED IN: signal transduction, protein amino acid phosphorylation, regulation of transcription, DNA-dependent; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: PAC motif (InterPro:IPR001610), Protein kinase, catalytic domain (InterPro:IPR000719), PAS fold (InterPro:IPR013767), PAS (InterPro:IPR000014), Serine-threonine/tyrosine-protein kinase (InterPro:IPR001245), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: PAS domain-containing protein tyrosine kinase family protein (TAIR:AT5G49470.3); Has 127928 Blast hits to 126175 proteins in 4896 species: Archae - 310; Bacteria - 16027; Metazoa - 47209; Fungi - 11347; Plants - 33277; Viruses - 520; Other Eukaryotes - 19238 (source: NCBI BLink).
    NP_564913.1
    • PAS domain-containing protein tyrosine kinase family protein; FUNCTIONS IN: protein serine/threonine/tyrosine kinase activity, kinase activity; INVOLVED IN: signal transduction, protein amino acid phosphorylation, regulation of transcription, DNA-dependent; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Serine/threonine-protein kinase domain (InterPro:IPR002290), PAS fold (InterPro:IPR013767), PAS (InterPro:IPR000014), Serine-threonine/tyrosine-protein kinase (InterPro:IPR001245), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase-like domain (InterPro:IPR011009), Protein kinase, catalytic domain (InterPro:IPR000719), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635); BEST Arabidopsis thaliana protein match is: PAS domain-containing protein tyrosine kinase family protein (TAIR:AT5G49470.3); Has 128751 Blast hits to 126912 proteins in 4876 species: Archae - 309; Bacteria - 16105; Metazoa - 47584; Fungi - 11405; Plants - 33369; Viruses - 523; Other Eukaryotes - 19456 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      25457033..25462847
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001084319.2 → NP_001077788.1  PAS domain-containing protein tyrosine kinase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001077788.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q93YU0, Q9C9V5
      Conserved Domains (2) summary
      cd13999
      Location:493 → 723
      STKc_MAP3K-like; Catalytic domain of Mitogen-Activated Protein Kinase (MAPK) Kinase Kinase-like Serine/Threonine kinases
      pfam00989
      Location:101 → 211
      PAS; PAS fold

    2. NM_105459.3 → NP_564913.1  PAS domain-containing protein tyrosine kinase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564913.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WFM4, F4HVH9, Q93YU0
      Conserved Domains (2) summary
      cd13999
      Location:493 → 738
      STKc_MAP3K-like; Catalytic domain of Mitogen-Activated Protein Kinase (MAPK) Kinase Kinase-like Serine/Threonine kinases
      pfam00989
      Location:101 → 211
      PAS; PAS fold

    3. NM_001334334.1 → NP_001320568.1  PAS domain-containing protein tyrosine kinase family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q93YU0, Q9C9V5
      Conserved Domains (2) summary
      cd13999
      Location:493 → 723
      STKc_MAP3K-like; Catalytic domain of Mitogen-Activated Protein Kinase (MAPK) Kinase Kinase-like Serine/Threonine kinases
      pfam00989
      Location:101 → 211
      PAS; PAS fold

    4. NM_001334335.1 → NP_001320569.1  PAS domain-containing protein tyrosine kinase family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AN76
    Nucleotide Protein
    Heading Accession and Version

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