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    CYP704B1 cytochrome P450, family 704, subfamily B, polypeptide 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843283, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CYP704B1
    Official Full Name
    cytochrome P450, family 704, subfamily B, polypeptide 1
    Primary source
    TAIR:AT1G69500
    Locus tag
    AT1G69500
    See related
    Araport:AT1G69500
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ''cytochrome P450; cytochrome P450; F10D13.15; F10D13_15; family 704; polypeptide 1; polypeptide 1''; subfamily B
    Summary
    Encodes a cytochrome P450, designated CYP704B1. Expressed in the developing anthers. Essential for pollen exine development. Mutations in CYP704B1 result in impaired pollen walls that lack a normal exine layer and exhibit a characteristic striped surface, termed zebra phenotype. Heterologous expression of CYP704B1 in yeast cells demonstrated that it catalyzes omega-hydroxylation of long-chain fatty acids, implicating these molecules in sporopollenin synthesis.
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    Genomic context

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    See CYP704B1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    6
    Sequence:
    Chromosome: 1; NC_003070.9 (26123940..26126057)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Ribosomal L32p protein family Neighboring gene NAC-like, activated by AP3/PI Neighboring gene cAMP-regulated phosphoprotein 19-related protein Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. CYP704B1 is a long-chain fatty acid omega-hydroxylase essential for sporopollenin synthesis in pollen of Arabidopsis. Dobritsa AA, et al. Plant Physiol, 2009 Oct. PMID 19700560, Free PMC Article
    2. A large-scale genetic screen in Arabidopsis to identify genes involved in pollen exine production. Dobritsa AA, et al. Plant Physiol, 2011 Oct. PMID 21849515, Free PMC Article
    3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Mutations in CYP704B1 result in impaired pollen walls that lack a normal exine layer and exhibit a characteristic striped surface, termed zebra phenotype. [CYP704B1]
      Title: CYP704B1 is a long-chain fatty acid omega-hydroxylase essential for sporopollenin synthesis in pollen of Arabidopsis.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    NM_105617.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables alkane 1-monooxygenase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables long-chain fatty acid omega-hydroxylase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within pollen exine formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within sporopollenin biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    cytochrome P450, family 704, subfamily B, polypeptide 1
    NP_177109.3
    • ''cytochrome P450, family 704, subfamily B, polypeptide 1'' (CYP704B1); CONTAINS InterPro DOMAIN/s: Cytochrome P450 (InterPro:IPR001128), Cytochrome P450, E-class, group I (InterPro:IPR002401); BEST Arabidopsis thaliana protein match is: cytochrome P450, family 704, subfamily A, polypeptide 2 (TAIR:AT2G45510.1); Has 24652 Blast hits to 24553 proteins in 1381 species: Archae - 44; Bacteria - 2338; Metazoa - 9085; Fungi - 5048; Plants - 7257; Viruses - 3; Other Eukaryotes - 877 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      26123940..26126057
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105617.3 → NP_177109.3  cytochrome P450, family 704, subfamily B, polypeptide 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_177109.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0MEF2, Q8GWJ5, Q9C788
      UniProtKB/TrEMBL
      A0A178W3Z4, A0A654EP57
      Conserved Domains (1) summary
      PLN03195
      Location:1 → 524
      PLN03195; fatty acid omega-hydroxylase; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9C788.1

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