U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CLH2 chlorophyllase 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834408, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CLH2
    Official Full Name
    chlorophyllase 2
    Primary source
    TAIR:AT5G43860
    Locus tag
    AT5G43860
    See related
    Araport:AT5G43860
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA CHLOROPHYLLASE 2; ATCLH2; chlorophyllase 2; MQD19.22; MQD19_22
    Summary
    Encodes a chlorophyllase, the first enzyme in chlorophyll degradation. It catalyzes the hydrolysis of the ester bond to chlorophyllide and phytol. AtCLH2 has a typical signal sequence for the chloroplast. Gene expression does not respond to methyljasmonate, a known promoter of senescence and chlorophyll degradation.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CLH2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    2
    Sequence:
    Chromosome: 5; NC_003076.8 (17630426..17632338)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene heat shock transcription factor A6A Neighboring gene RmlC-like cupins superfamily protein Neighboring gene auxin canalization protein (DUF828) Neighboring gene methyl-coenzyme M reductase II subunit gamma, putative (DUF3741) Neighboring gene Flavin-binding monooxygenase family protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Subcellular localization of chlorophyllase2 reveals it is not involved in chlorophyll degradation during senescence in Arabidopsis thaliana. Hu X, et al. Plant Sci, 2020 Jan. PMID 31779896
    2. Expression of enzymes involved in chlorophyll catabolism in Arabidopsis is light controlled. Banas AK, et al. Plant Physiol, 2011 Nov. PMID 21896889, Free PMC Article
    3. Repression of AtCLH1 expression results in a decrease in the ratio of chlorophyll a/b but doesnot affect the rate of chlorophyll degradation during leaf senescence. Zhou X, et al. Zhi Wu Sheng Li Yu Fen Zi Sheng Wu Xue Xue Bao, 2007 Dec. PMID 18349515
    4. The chlorophyllases AtCLH1 and AtCLH2 are not essential for senescence-related chlorophyll breakdown in Arabidopsis thaliana. Schenk N, et al. FEBS Lett, 2007 Nov 27. PMID 17996203
    5. Chlorophyllase 1, a damage control enzyme, affects the balance between defense pathways in plants. Kariola T, et al. Plant Cell, 2005 Jan. PMID 15598807, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Based on the collective data, the authors conclude that CLH2 is not involved in Chl breakdown during senescence in Arabidopsis.
      Title: Subcellular localization of chlorophyllase2 reveals it is not involved in chlorophyll degradation during senescence in Arabidopsis thaliana.
    2. The levels of mRNA of two enzymes involved in chlorophyll catabolism in Arabidopsis, products of two chlorophyllase genes, AtCLH1 and AtCLH2, dramatically increase upon illumination with white light.
      Title: Expression of enzymes involved in chlorophyll catabolism in Arabidopsis is light controlled.
    3. Data conclude that AtCLH2 might be required at the initial stage of leaf senescence, quite likely playing a role in converting Chl b to a.
      Title: Repression of AtCLH1 expression results in a decrease in the ratio of chlorophyll a/b but doesnot affect the rate of chlorophyll degradation during leaf senescence.
    4. AtCLHs are not required for senescence-related chlorophyll breakdown in vivo and propose that genuine chlorophyllase has not yet been molecularly identified
      Title: The chlorophyllases AtCLH1 and AtCLH2 are not essential for senescence-related chlorophyll breakdown in Arabidopsis thaliana.
    5. We propose that AtCLH1 is involved in plant damage control and can modulate the balance between different plant defense pathways.
      Title: Chlorophyllase 1, a damage control enzyme, affects the balance between defense pathways in plants.
    Submit: New GeneRIF Correction

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help
    NM_123753.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables chlorophyllase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables chlorophyllase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within chlorophyll catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in chlorophyll catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    chlorophyllase 2
    NP_199199.1
    • chlorophyllase 2 (CLH2); CONTAINS InterPro DOMAIN/s: Chlorophyllase-like (InterPro:IPR010821), Chlorophyllase, chloroplast (InterPro:IPR017395); BEST Arabidopsis thaliana protein match is: chlorophyllase 1 (TAIR:AT1G19670.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      17630426..17632338
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_123753.3 → NP_199199.1  chlorophyllase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_199199.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9M7I7
      UniProtKB/TrEMBL
      A0A178UA51, A0A5S9YBV0, A0A654G7T3
      Conserved Domains (1) summary
      PLN00021
      Location:1 → 318
      PLN00021; chlorophyllase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9M7I7.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools