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    basic helix-loop-helix (bHLH) DNA-binding superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834912, updated on 18-Sep-2024

    Summary

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    Official Full Name
    basic helix-loop-helix (bHLH) DNA-binding superfamily protein
    Primary source
    TAIR:AT5G48560
    Locus tag
    AT5G48560
    See related
    Araport:AT5G48560
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    CIB2; CRY2-interacting bHLH 2; K15N18.2; K15N18_2
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    6
    Sequence:
    Chromosome: 5; NC_003076.8 (19683809..19687187)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene low-molecular-weight cysteine-rich 1 Neighboring gene histidine triad nucleotide-binding 3 Neighboring gene F-box associated ubiquitination effector family protein Neighboring gene FKBP-type peptidyl-prolyl cis-trans isomerase family protein Neighboring gene mediator of RNA polymerase II transcription subunit-like protein, putative (DUF1216)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Multiple bHLH proteins form heterodimers to mediate CRY2-dependent regulation of flowering-time in Arabidopsis. Liu Y, et al. PLoS Genet, 2013. PMID 24130508, Free PMC Article
    2. An integrative approach to the identification of Arabidopsis and rice genes involved in xylan and secondary wall development. Oikawa A, et al. PLoS One, 2010 Nov 23. PMID 21124849, Free PMC Article
    3. The development of protein microarrays and their applications in DNA-protein and protein-protein interaction analyses of Arabidopsis transcription factors. Gong W, et al. Mol Plant, 2008 Jan. PMID 19802365, Free PMC Article
    4. The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity. Heim MA, et al. Mol Biol Evol, 2003 May. PMID 12679534
    5. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Riechmann JL, et al. Science, 2000 Dec 15. PMID 11118137

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    NM_124232.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of DNA-templated transcription TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in response to blue light IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    basic helix-loop-helix (bHLH) DNA-binding superfamily protein
    NP_199667.1
    • basic helix-loop-helix (bHLH) DNA-binding superfamily protein; FUNCTIONS IN: DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of transcription; LOCATED IN: nucleus; EXPRESSED IN: 14 plant structures; EXPRESSED DURING: LP.06 six leaves visible, LP.04 four leaves visible, 4 anthesis, petal differentiation and expansion stage, LP.08 eight leaves visible; CONTAINS InterPro DOMAIN/s: Helix-loop-helix DNA-binding domain (InterPro:IPR001092), Helix-loop-helix DNA-binding (InterPro:IPR011598); BEST Arabidopsis thaliana protein match is: basic helix-loop-helix (bHLH) DNA-binding superfamily protein (TAIR:AT3G07340.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      19683809..19687187
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001344777.1 → NP_001330141.1  basic helix-loop-helix (bHLH) DNA-binding superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UME9, A0A1P8B9W1

    2. NM_124232.4 → NP_199667.1  basic helix-loop-helix (bHLH) DNA-binding superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_199667.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8S3D4, Q9FJL4
      UniProtKB/TrEMBL
      A0A178UME9
      Conserved Domains (1) summary
      smart00353
      Location:313 → 362
      HLH; helix loop helix domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FJL4.1

    Gene LinkOut

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