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    CCX4 cation calcium exchanger 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841851, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CCX4
    Official Full Name
    cation calcium exchanger 4
    Primary source
    TAIR:AT1G54115
    Locus tag
    AT1G54115
    See related
    Araport:AT1G54115
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATCCX4; cation calcium exchanger 4; CATION CALCIUM EXCHANGER 4
    Summary
    Involved in cation (Na and K) homeostasis.
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    Genomic context

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    See CCX4 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    1
    Sequence:
    Chromosome: 1; NC_003070.9 (20201806..20204412)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene aldehyde dehydrogenase 7B4 Neighboring gene Membrane fusion protein Use1 Neighboring gene uncharacterized protein Neighboring gene RELA/SPOT homolog 3 Neighboring gene TATA binding protein associated factor 21kDa subunit

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Golgi apparatus-localized CATION CALCIUM EXCHANGER4 promotes osmotolerance of Arabidopsis. Kanamori K, et al. Plant Physiol, 2024 Jan 31. PMID 37878763, Free PMC Article
    2. Suppression of class I compensated cell enlargement by xs2 mutation is mediated by salicylic acid signaling. Fujikura U, et al. PLoS Genet, 2020 Jun. PMID 32584819, Free PMC Article
    3. CCX1, a Putative Cation/Ca2+ Exchanger, Participates in Regulation of Reactive Oxygen Species Homeostasis and Leaf Senescence. Li Z, et al. Plant Cell Physiol, 2016 Dec. PMID 27986916
    4. AtCCX3 is an Arabidopsis endomembrane H+ -dependent K+ transporter. Morris J, et al. Plant Physiol, 2008 Nov. PMID 18775974, Free PMC Article
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Golgi apparatus-localized CATION CALCIUM EXCHANGER4 promotes osmotolerance of Arabidopsis.
      Title: Golgi apparatus-localized CATION CALCIUM EXCHANGER4 promotes osmotolerance of Arabidopsis.
    2. Suppression of class I compensated cell enlargement by xs2 mutation is mediated by salicylic acid signaling.
      Title: Suppression of class I compensated cell enlargement by xs2 mutation is mediated by salicylic acid signaling.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    NM_104289.3

    Gene Ontology Provided by TAIR

    Process Evidence Code Pubs
    acts_upstream_of_or_within leaf senescence IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within monoatomic cation transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    cation calcium exchanger 4
    NP_564650.1
    • cation calcium exchanger 4 (CCX4); FUNCTIONS IN: cation:cation antiporter activity; INVOLVED IN: cation transport, cellular cation homeostasis; LOCATED IN: integral to membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Sodium/calcium exchanger membrane region (InterPro:IPR004837); BEST Arabidopsis thaliana protein match is: cation exchanger 9 (TAIR:AT3G14070.1); Has 4016 Blast hits to 3229 proteins in 801 species: Archae - 54; Bacteria - 848; Metazoa - 1841; Fungi - 309; Plants - 226; Viruses - 0; Other Eukaryotes - 738 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      20201806..20204412
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_104289.3 → NP_564650.1  cation calcium exchanger 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564650.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SYG9
      UniProtKB/TrEMBL
      A0A178W8Z2, A0A5S9WM64, A0A654EIA7
      Conserved Domains (1) summary
      PLN03151
      Location:1 → 644
      PLN03151; cation/calcium exchanger; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SYG9.1

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