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    MLO14 Seven transmembrane MLO family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839211, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MLO14
    Official Full Name
    Seven transmembrane MLO family protein
    Primary source
    TAIR:AT1G26700
    Locus tag
    AT1G26700
    See related
    Araport:AT1G26700
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATMLO14; MILDEW RESISTANCE LOCUS O 14; T24P13.8; T24P13_8
    Summary
    A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO14 belongs to the clade I, with AtMLO4 and AtMLO11. The gene is expressed during early seedling growth, in developing primary root, and particularly in root tips of 10-day old seedlings; it was not expressed in leaves or flowers, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s).
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    Genomic context

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    See MLO14 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    16
    Sequence:
    Chromosome: 1; NC_003070.9 (9227378..9232437)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene transcriptional factor B3 family protein Neighboring gene emp24/gp25L/p24 family/GOLD family protein Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385
    2. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Seven transmembrane MLO family protein
    NP_001319086.1
    • MILDEW RESISTANCE LOCUS O 14 (MLO14); FUNCTIONS IN: calmodulin binding; INVOLVED IN: cell death, defense response; LOCATED IN: integral to membrane, plasma membrane; EXPRESSED IN: 12 plant structures; EXPRESSED DURING: 4 anthesis, LP.10 ten leaves visible, F mature embryo stage, 4 leaf senescence stage, LP.08 eight leaves visible; CONTAINS InterPro DOMAIN/s: Mlo-related protein (InterPro:IPR004326); BEST Arabidopsis thaliana protein match is: Seven transmembrane MLO family protein (TAIR:AT5G53760.2); Has 532 Blast hits to 521 proteins in 52 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 2; Plants - 523; Viruses - 0; Other Eukaryotes - 7 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      9227378..9232437
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001332726.1 → NP_001319086.1  Seven transmembrane MLO family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q94KB1, Q9LQY2
      UniProtKB/TrEMBL
      A0A178W8B8, A0A5S9W1E0
      Conserved Domains (1) summary
      pfam03094
      Location:9 → 468
      Mlo; Mlo family

    2. NM_102433.1 → NP_564257.1  Seven transmembrane MLO family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564257.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q94KB1, Q9LQY2
      UniProtKB/TrEMBL
      A0A178W8B8, A0A5S9W1E0
      Conserved Domains (1) summary
      pfam03094
      Location:9 → 468
      Mlo; Mlo family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q94KB1.1

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