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    IMPA-6 importin alpha isoform 6 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839517, updated on 18-Sep-2024

    Summary

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    Official Symbol
    IMPA-6
    Official Full Name
    importin alpha isoform 6
    Primary source
    TAIR:AT1G02690
    Locus tag
    AT1G02690
    See related
    Araport:AT1G02690
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    importin alpha isoform 6; T14P4.3; T14P4_3
    Summary
    Putative importin alpha isoform. When overexpressed can rescue the impa-4 decreased transformation susceptibility phenotype.
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    Genomic context

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    See IMPA-6 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    10
    Sequence:
    Chromosome: 1; NC_003070.9 (584134..587327)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene ncRNA Neighboring gene GATA transcription factor-like protein Neighboring gene uncharacterized protein Neighboring gene glycine-rich protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The intrinsically disordered N-terminal region of AtREM1.3 remorin protein mediates protein-protein interactions. Marín M, et al. J Biol Chem, 2012 Nov 16. PMID 23027878, Free PMC Article
    2. Telomerase Interaction Partners-Insight from Plants. Fulnečková J, et al. Int J Mol Sci, 2021 Dec 29. PMID 35008793, Free PMC Article
    3. Tandem affinity purification of AtTERT reveals putative interaction partners of plant telomerase in vivo. Majerská J, et al. Protoplasma, 2017 Jul. PMID 27853871
    4. Protein and metabolite composition of Arabidopsis stress granules. Kosmacz M, et al. New Phytol, 2019 May. PMID 30664249
    5. Identification and characterization of nuclear pore complex components in Arabidopsis thaliana. Tamura K, et al. Plant Cell, 2010 Dec. PMID 21189294, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_100149.4
    NM_202014.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables nuclear import signal receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein import into nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytoplasmic stress granule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    importin alpha isoform 6
    NP_171769.1
    • importin alpha isoform 6 (IMPA-6); FUNCTIONS IN: protein transporter activity, binding; INVOLVED IN: intracellular protein transport, protein import into nucleus; LOCATED IN: nucleus, nuclear pore, cytoplasm; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: Importin-alpha-like, importin-beta-binding domain (InterPro:IPR002652), Armadillo-like helical (InterPro:IPR011989), Armadillo (InterPro:IPR000225), Armadillo-type fold (InterPro:IPR016024); BEST Arabidopsis thaliana protein match is: ARM repeat superfamily protein (TAIR:AT4G02150.1); Has 4537 Blast hits to 3341 proteins in 295 species: Archae - 4; Bacteria - 37; Metazoa - 1783; Fungi - 593; Plants - 1355; Viruses - 0; Other Eukaryotes - 765 (source: NCBI BLink).
    NP_973743.1
    • importin alpha isoform 6 (IMPA-6); FUNCTIONS IN: protein transporter activity, binding; INVOLVED IN: intracellular protein transport, protein import into nucleus; LOCATED IN: nucleus, nuclear pore, cytoplasm; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: Importin-alpha-like, importin-beta-binding domain (InterPro:IPR002652), Armadillo-like helical (InterPro:IPR011989), Armadillo (InterPro:IPR000225), Armadillo-type fold (InterPro:IPR016024); BEST Arabidopsis thaliana protein match is: ARM repeat superfamily protein (TAIR:AT4G02150.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      584134..587327
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_100149.4 → NP_171769.1  importin alpha isoform 6 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_171769.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FWY7
      UniProtKB/TrEMBL
      A0A178WGP2, A0A654E7G9
      Conserved Domains (2) summary
      COG5064
      Location:10 → 536
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      sd00043
      Location:248 → 273
      ARM; armadillo repeat [structural motif]

    2. NM_202014.1 → NP_973743.1  importin alpha isoform 6 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_973743.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WGP2, F4HXL3
      Conserved Domains (4) summary
      COG5064
      Location:10 → 537
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00020
      Location:248 → 361
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      pfam01749
      Location:8 → 97
      IBB; Importin beta binding domain
      sd00043
      Location:249 → 274
      ARM; armadillo repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FWY7.1

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