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    ACT8 actin 8 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841347, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ACT8
    Official Full Name
    actin 8
    Primary source
    TAIR:AT1G49240
    Locus tag
    AT1G49240
    See related
    Araport:AT1G49240
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    actin 8; F27J15.1; F27J15_1; FIZ1; FRIZZY AND KINKED SHOOTS
    Summary
    Member of a subclass of actins composed of ACT2 and ACT8. Its mRNA is strongly expressed in strongly expressed in leaves, roots, stems, flowers, pollen, and siliques. However, protein expression, assayed by a ACT8:GUS fusion reporter, is very low in pollen.
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    Genomic context

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    See ACT8 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    5
    Sequence:
    Chromosome: 1; NC_003070.9 (18215800..18218339)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene RING/U-box superfamily protein Neighboring gene uncharacterized protein Neighboring gene RING/U-box superfamily protein Neighboring gene Prefoldin chaperone subunit family protein Neighboring gene ATP-dependent DNA ligase Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Plant vegetative and animal cytoplasmic actins share functional competence for spatial development with protists. Kandasamy MK, et al. Plant Cell, 2012 May. PMID 22589468, Free PMC Article
    2. A single vegetative actin isovariant overexpressed under the control of multiple regulatory sequences is sufficient for normal Arabidopsis development. Kandasamy MK, et al. Plant Cell, 2009 Mar. PMID 19304937, Free PMC Article
    3. Arabidopsis AIP1-2 restricted by WER-mediated patterning modulates planar polarity. Kiefer CS, et al. Development, 2015 Jan 1. PMID 25428588, Free PMC Article
    4. An inositol polyphosphate 5-phosphatase functions in PHOTOTROPIN1 signaling in Arabidopis by altering cytosolic Ca2+. Chen X, et al. Plant Cell, 2008 Feb. PMID 18252844, Free PMC Article
    5. Proteomic survey of copper-binding proteins in Arabidopsis roots by immobilized metal affinity chromatography and mass spectrometry. Kung CC, et al. Proteomics, 2006 May. PMID 16526091

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    NM_103814.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables copper ion binding HDA PubMed 
    enables mRNA binding HDA PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within root hair cell tip growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast envelope HDA PubMed 
    located_in chloroplast stroma HDA PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 
    located_in nucleus HDA PubMed 
    located_in plant-type vacuole HDA PubMed 
    located_in plasmodesma HDA PubMed 

    General protein information

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    Preferred Names
    actin 8
    NP_175350.1
    • actin 8 (ACT8); FUNCTIONS IN: copper ion binding, structural constituent of cytoskeleton; INVOLVED IN: response to salt stress, root hair cell tip growth, cytoskeleton organization; LOCATED IN: plasma membrane, chloroplast, vacuole; EXPRESSED IN: 30 plant structures; EXPRESSED DURING: 17 growth stages; CONTAINS InterPro DOMAIN/s: Actin, conserved site (InterPro:IPR004001), Actin/actin-like (InterPro:IPR004000), Actin/actin-like conserved site (InterPro:IPR020902); BEST Arabidopsis thaliana protein match is: actin 2 (TAIR:AT3G18780.2); Has 15146 Blast hits to 14753 proteins in 3039 species: Archae - 6; Bacteria - 12; Metazoa - 5709; Fungi - 5217; Plants - 1599; Viruses - 2; Other Eukaryotes - 2601 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      18215800..18218339
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_103814.4 → NP_175350.1  actin 8 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_175350.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q41933, Q96293, Q9M9C2
      UniProtKB/TrEMBL
      A0A178WDV5, A0A5S9WNE1, Q8LB94
      Conserved Domains (1) summary
      cl17037
      Location:5 → 377
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q96293.2

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