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    WRKY23 WRKY DNA-binding protein 23 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819339, updated on 18-Sep-2024

    Summary

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    Official Symbol
    WRKY23
    Official Full Name
    WRKY DNA-binding protein 23
    Primary source
    TAIR:AT2G47260
    Locus tag
    AT2G47260
    See related
    Araport:AT2G47260
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATWRKY23; T8I13.10; WRKY DNA-binding protein 23; WRKY DNA-BINDING PROTEIN 23
    Summary
    Encodes a member of WRKY Transcription Factor; Group I. Involved in nematode feeding site establishment.
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    Genomic context

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    See WRKY23 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    3
    Sequence:
    Chromosome: 2; NC_003071.7 (19404802..19407098, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene long chain acyl-CoA synthetase Neighboring gene RNA helicase family protein Neighboring gene transcription factor UPBEAT protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. WRKY23 is a component of the transcriptional network mediating auxin feedback on PIN polarity. Prát T, et al. PLoS Genet, 2018 Jan. PMID 29377885, Free PMC Article
    2. Tightly controlled WRKY23 expression mediates Arabidopsis embryo development. Grunewald W, et al. EMBO Rep, 2013 Dec. PMID 24157946, Free PMC Article
    3. Transcription factor WRKY23 assists auxin distribution patterns during Arabidopsis root development through local control on flavonol biosynthesis. Grunewald W, et al. Proc Natl Acad Sci U S A, 2012 Jan 31. PMID 22307611, Free PMC Article
    4. A role for AtWRKY23 in feeding site establishment of plant-parasitic nematodes. Grunewald W, et al. Plant Physiol, 2008 Sep. PMID 18599655, Free PMC Article
    5. Transcriptional activation by WRKY23 and derepression by removal of bHLH041 coordinately establish callus pluripotency in Arabidopsis regeneration. Xu C, et al. Plant Cell, 2023 Dec 21. PMID 37804093, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Gain- and loss-of-function mutants confirmed a role for WRKY23 in mediating the auxin effect on the PIN polarity. Accordingly, processes requiring auxin-mediated PIN polarity rearrangements, such as vascular tissue development during leaf venation, showed a higher WRKY23 expression and required the WRKY23 activity.
      Title: WRKY23 is a component of the transcriptional network mediating auxin feedback on PIN polarity.
    2. Knocking down WRKY23 transcript levels or expression of a dominant-negative WRKY23 affected both apical-basal axis formation as well as installation of the root stem cell niche.
      Title: Tightly controlled WRKY23 expression mediates Arabidopsis embryo development.
    3. results suggest a model in which WRKY23 is part of a transcriptional feedback loop of auxin on its own transport through local regulation of flavonol biosynthesis
      Title: Transcription factor WRKY23 assists auxin distribution patterns during Arabidopsis root development through local control on flavonol biosynthesis.
    4. WRKY23 is expressed during the early stages of nematode feeding site establishment.
      Title: A role for AtWRKY23 in feeding site establishment of plant-parasitic nematodes.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_130294.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in callus formation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of DNA-templated transcription initiation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within protein localization involved in auxin polar transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to auxin IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to auxin IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to nematode IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    WRKY DNA-binding protein 23
    NP_182248.1
    • WRKY DNA-binding protein 23 (WRKY23); CONTAINS InterPro DOMAIN/s: DNA-binding WRKY (InterPro:IPR003657), Transcription factor, WRKY group IIc (InterPro:IPR017396); BEST Arabidopsis thaliana protein match is: WRKY family transcription factor (TAIR:AT3G62340.1); Has 3541 Blast hits to 3088 proteins in 202 species: Archae - 0; Bacteria - 3; Metazoa - 11; Fungi - 7; Plants - 3503; Viruses - 0; Other Eukaryotes - 17 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      19404802..19407098 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_130294.4 → NP_182248.1  WRKY DNA-binding protein 23 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_182248.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O22900
      UniProtKB/TrEMBL
      A0A178VQ40, A0A5S9X7R5, A0A654F2Q1
      Conserved Domains (1) summary
      smart00774
      Location:173 → 230
      WRKY; DNA binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O22900.1

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