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    POLA2 DNA polymerase alpha 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843086, updated on 18-Sep-2024

    Summary

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    Official Symbol
    POLA2
    Official Full Name
    DNA polymerase alpha 2
    Primary source
    TAIR:AT1G67630
    Locus tag
    AT1G67630
    See related
    Araport:AT1G67630
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    DNA polymerase alpha 2; EMB2814; EMBRYO DEFECTIVE 2814; F12B7.19; F12B7_19
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    Genomic context

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    See POLA2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    15
    Sequence:
    Chromosome: 1; NC_003070.9 (25344440..25348406, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene F-box family protein Neighboring gene pseudo Neighboring gene phosphatidylinositol 4-kinase gamma-like protein Neighboring gene Transmembrane amino acid transporter family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins. Heazlewood JL, et al. Plant Cell, 2004 Jan. PMID 14671022, Free PMC Article
    2. Analysis of the Arabidopsis cytosolic proteome highlights subcellular partitioning of central plant metabolism. Ito J, et al. J Proteome Res, 2011 Apr 1. PMID 21166475
    3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_105430.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    NOT located_in cytosol RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    DNA polymerase alpha 2
    NP_176930.2
    • DNA polymerase alpha 2 (POLA2); FUNCTIONS IN: DNA binding, DNA-directed DNA polymerase activity; INVOLVED IN: DNA replication; LOCATED IN: mitochondrion; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA polymerase alpha, subunit B N-terminal (InterPro:IPR013627), DNA polymerase alpha, subunit B (InterPro:IPR016722), DNA polymerase alpha/epsilon, subunit B (InterPro:IPR007185); Has 415 Blast hits to 412 proteins in 190 species: Archae - 0; Bacteria - 0; Metazoa - 175; Fungi - 140; Plants - 46; Viruses - 0; Other Eukaryotes - 54 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      25344440..25348406 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105430.3 → NP_176930.2  DNA polymerase alpha 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_176930.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W3X2, A0A5S9WQA2, F4HTP2, Q8GWX4
      Conserved Domains (1) summary
      pfam04042
      Location:362 → 571
      DNA_pol_E_B; DNA polymerase alpha/epsilon subunit B
    Nucleotide Protein
    Heading Accession and Version

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