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    RH8 RNAhelicase-like 8 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828042, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RH8
    Official Full Name
    RNAhelicase-like 8
    Primary source
    TAIR:AT4G00660
    Locus tag
    AT4G00660
    See related
    Araport:AT4G00660
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATRH8; F6N23.6; F6N23_6; RNAhelicase-like 8
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    Genomic context

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    See RH8 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    10
    Sequence:
    Chromosome: 4; NC_003075.7 (274252..278737)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene FRIGIDA-like protein Neighboring gene ncRNA Neighboring gene Fe superoxide dismutase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Remorin family protein Neighboring gene actin depolymerizing factor 8 Neighboring gene UB-like protease 1B Neighboring gene ncRNA Neighboring gene Spc97/Spc98 family of spindle pole body (SBP) component

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A DEAD-box RNA helicase, RH8, is critical for regulation of ABA signalling and the drought stress response via inhibition of PP2CA activity. Baek W, et al. Plant Cell Environ, 2018 Jul. PMID 29574779
    2. A host RNA helicase-like protein, AtRH8, interacts with the potyviral genome-linked protein, VPg, associates with the virus accumulation complex, and is essential for infection. Huang TS, et al. Plant Physiol, 2010 Jan. PMID 19880609, Free PMC Article
    3. DHH1/DDX6-like RNA helicases maintain ephemeral half-lives of stress-response mRNAs. Chantarachot T, et al. Nat Plants, 2020 Jun. PMID 32483330
    4. A NYN domain protein directly interacts with DECAPPING1 and is required for phyllotactic pattern. Schiaffini M, et al. Plant Physiol, 2022 Feb 4. PMID 34791434, Free PMC Article
    5. Identification of BZR1-interacting proteins as potential components of the brassinosteroid signaling pathway in Arabidopsis through tandem affinity purification. Wang C, et al. Mol Cell Proteomics, 2013 Dec. PMID 24019147, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. DHH1/DDX6-like RNA helicases maintain ephemeral half-lives of stress-response mRNAs.
      Title: DHH1/DDX6-like RNA helicases maintain ephemeral half-lives of stress-response mRNAs.
    2. critical for regulation of ABA signalling and the drought stress response via inhibition of PP2CA activity
      Title: A DEAD-box RNA helicase, RH8, is critical for regulation of ABA signalling and the drought stress response via inhibition of PP2CA activity.
    3. AtRH8, interacting with potyvirus protein VPg, is a host factor required for the potyvirus infection process. [RH8]
      Title: A host RNA helicase-like protein, AtRH8, interacts with the potyviral genome-linked protein, VPg, associates with the virus accumulation complex, and is essential for infection.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_116291.5
    NM_179204.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables RNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA binding HDA PubMed 
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within intracellular transport of viral protein in host cell IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within viral process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 

    General protein information

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    Preferred Names
    RNAhelicase-like 8
    NP_191975.2
    • RNAhelicase-like 8 (RH8); FUNCTIONS IN: helicase activity, nucleic acid binding, ATP-dependent helicase activity, ATP binding; INVOLVED IN: viral reproduction, virus-host interaction; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: RNA helicase, DEAD-box type, Q motif (InterPro:IPR014014), DNA/RNA helicase, DEAD/DEAH box type, N-terminal (InterPro:IPR011545), RNA helicase, ATP-dependent, DEAD-box, conserved site (InterPro:IPR000629), DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: DEA(D/H)-box RNA helicase family protein (TAIR:AT2G45810.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_849535.1
    • RNAhelicase-like 8 (RH8); FUNCTIONS IN: helicase activity, nucleic acid binding, ATP binding, ATP-dependent helicase activity; INVOLVED IN: viral reproduction, virus-host interaction; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: RNA helicase, DEAD-box type, Q motif (InterPro:IPR014014), DNA/RNA helicase, DEAD/DEAH box type, N-terminal (InterPro:IPR011545), RNA helicase, ATP-dependent, DEAD-box, conserved site (InterPro:IPR000629), DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: DEA(D/H)-box RNA helicase family protein (TAIR:AT2G45810.1); Has 44948 Blast hits to 43709 proteins in 3097 species: Archae - 707; Bacteria - 21922; Metazoa - 6580; Fungi - 4983; Plants - 2686; Viruses - 56; Other Eukaryotes - 8014 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      274252..278737
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_116291.5 → NP_191975.2  RNAhelicase-like 8 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_191975.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O65275, Q8RXK6, Q9ZS12
      UniProtKB/TrEMBL
      A0A178UXT2, A0A7G2EV33
      Conserved Domains (2) summary
      cd18787
      Location:343 → 472
      SF2_C_DEAD; C-terminal helicase domain of the DEAD box helicases
      cd17940
      Location:133 → 333
      DEADc_DDX6; DEAD-box helicase domain of DEAD box protein 6

    2. NM_179204.2 → NP_849535.1  RNAhelicase-like 8 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849535.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O65275, Q8RXK6, Q9ZS12
      UniProtKB/TrEMBL
      A0A178UXT2, A0A7G2EV33
      Conserved Domains (2) summary
      cd18787
      Location:343 → 472
      SF2_C_DEAD; C-terminal helicase domain of the DEAD box helicases
      cd17940
      Location:133 → 333
      DEADc_DDX6; DEAD-box helicase domain of DEAD box protein 6
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8RXK6.1

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