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    WNK5 with no lysine (K) kinase 5 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824326, updated on 18-Sep-2024

    Summary

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    Official Symbol
    WNK5
    Official Full Name
    with no lysine (K) kinase 5
    Primary source
    TAIR:AT3G51630
    Locus tag
    AT3G51630
    See related
    Araport:AT3G51630
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATWNK5; with no lysine (K) kinase 5; ZIK1
    Summary
    Encodes a member of the WNK family (9 members in all) of protein kinases, the structural design of which is clearly distinct from those of other known protein kinases, such as receptor-like kinases and mitogen-activated protein kinases.
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    Genomic context

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    See WNK5 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    7
    Sequence:
    Chromosome: 3; NC_003074.8 (19148871..19152193)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene ATP-dependent helicase/deoxyribonuclease subunit B Neighboring gene PAP/OAS1 substrate-binding domain superfamily Neighboring gene miscRNA Neighboring gene stress response NST1-like protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The plant WNK gene family and regulation of flowering time in Arabidopsis. Wang Y, et al. Plant Biol (Stuttg), 2008 Sep. PMID 18761494
    2. Compilation and characterization of a novel WNK family of protein kinases in Arabiodpsis thaliana with reference to circadian rhythms. Nakamichi N, et al. Biosci Biotechnol Biochem, 2002 Nov. PMID 12506983
    3. Toward an interaction map of the two-component signaling pathway of Arabidopsis thaliana. Dortay H, et al. J Proteome Res, 2008 Sep. PMID 18642946
    4. MAPK target networks in Arabidopsis thaliana revealed using functional protein microarrays. Popescu SC, et al. Genes Dev, 2009 Jan 1. PMID 19095804, Free PMC Article
    5. Extensive signal integration by the phytohormone protein network. Altmann M, et al. Nature, 2020 Jul. PMID 32612234

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Miscellaneous features

    • Loc: 19149198-19149386 AT3G51630.uORF1
    NM_001203127.1
    NM_115022.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein histidine kinase binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein kinase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within photoperiodism, flowering IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within protein phosphorylation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    with no lysine (K) kinase 5
    NP_001190056.1
    • with no lysine (K) kinase 5 (WNK5); CONTAINS InterPro DOMAIN/s: Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: with no lysine (K) kinase 4 (TAIR:AT5G58350.1).
    NP_566954.2
    • with no lysine (K) kinase 5 (WNK5); CONTAINS InterPro DOMAIN/s: Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: with no lysine (K) kinase 4 (TAIR:AT5G58350.1); Has 105080 Blast hits to 104081 proteins in 3160 species: Archae - 97; Bacteria - 11520; Metazoa - 36773; Fungi - 10256; Plants - 28915; Viruses - 396; Other Eukaryotes - 17123 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      19148871..19152193
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001203127.1 → NP_001190056.1  with no lysine (K) kinase 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190056.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SCU5, Q9XFS5
      UniProtKB/TrEMBL
      A0A5S9XJV8, A0A654FEX2
      Conserved Domains (2) summary
      cd13983
      Location:23 → 283
      STKc_WNK; Catalytic domain of the Serine/Threonine kinase, With No Lysine (WNK) kinase
      pfam12202
      Location:357 → 398
      OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain

    2. NM_115022.3 → NP_566954.2  with no lysine (K) kinase 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566954.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SCU5, Q9XFS5
      UniProtKB/TrEMBL
      A0A5S9XJV8, A0A654FEX2
      Conserved Domains (2) summary
      cd13983
      Location:23 → 283
      STKc_WNK; Catalytic domain of the Serine/Threonine kinase, With No Lysine (WNK) kinase
      pfam12202
      Location:357 → 398
      OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SCU5.2

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