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    ATE1 arginine-tRNA protein transferase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830454, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ATE1
    Official Full Name
    arginine-tRNA protein transferase 1
    Primary source
    TAIR:AT5G05700
    Locus tag
    AT5G05700
    See related
    Araport:AT5G05700
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    arginine-tRNA protein transferase 1; ARGININE-TRNA PROTEIN TRANSFERASE 1; ATATE1; DELAYED LEAF SENESCENCE 1; DLS1; MJJ3.1; MJJ3_1
    Summary
    Encodes an arginyl-tRNA:protein transferase (ATE1), a component of the N-end rule pathway that targets protein degradation through the identity of the amino-terminal residue of specific protein substrates. Arabidopsis contains two ATE genes: At5g05700/ATE1, At3g11240/ATE2. Another component of the N-end rule pathway is At5g02310/PROTEOLYSIS6 (PRT6). PRT6 and ATE were shown to regulate seed after-ripening, seedling sugar sensitivity, seedling lipid breakdown, and abscisic acid (ABA) sensitivity of germination. Mutants of ATE1 also display delayed leaf senescence.
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    Genomic context

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    See ATE1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    6
    Sequence:
    Chromosome: 5; NC_003076.8 (1712670..1715731, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene signal recognition particle binding protein Neighboring gene uncharacterized protein Neighboring gene nuclear pore complex protein-like protein Neighboring gene Cytochrome P450 superfamily protein Neighboring gene Pleckstrin homology (PH) domain superfamily protein Neighboring gene RNA-binding (RRM/RBD/RNP motifs) family protein Neighboring gene anthranilate synthase alpha subunit 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A delayed leaf senescence mutant is defective in arginyl-tRNA:protein arginyltransferase, a component of the N-end rule pathway in Arabidopsis. Yoshida S, et al. Plant J, 2002 Oct. PMID 12366806
    2. Plant cysteine oxidases are dioxygenases that directly enable arginyl transferase-catalysed arginylation of N-end rule targets. White MD, et al. Nat Commun, 2017 Mar 23. PMID 28332493, Free PMC Article
    3. The N-end rule pathway regulates pathogen responses in plants. de Marchi R, et al. Sci Rep, 2016 May 13. PMID 27173012, Free PMC Article
    4. The N-end rule pathway promotes seed germination and establishment through removal of ABA sensitivity in Arabidopsis. Holman TJ, et al. Proc Natl Acad Sci U S A, 2009 Mar 17. PMID 19255443, Free PMC Article
    5. 14-3-3 proteins fine-tune plant nutrient metabolism. Shin R, et al. FEBS Lett, 2011 Jan 3. PMID 21094157

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001342833.1
    NM_120652.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables arginyl-tRNA--protein transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables arginyl-tRNA--protein transferase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within defense response to fungus IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within leaf senescence IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of lipid catabolic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of seed germination IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within response to abscisic acid IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    arginine-tRNA protein transferase 1
    NP_196189.1
    • arginine-tRNA protein transferase 1 (ATE1); CONTAINS InterPro DOMAIN/s: Arginine-tRNA-protein transferase, N-terminal (InterPro:IPR007471), Arginine-tRNA-protein transferase 1, eukaryotic (InterPro:IPR017137), Arginine-tRNA-protein transferase, C-terminal (InterPro:IPR007472); BEST Arabidopsis thaliana protein match is: arginine-tRNA protein transferase 2 (TAIR:AT3G11240.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      1712670..1715731 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_120652.4 → NP_196189.1  arginine-tRNA protein transferase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_196189.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q56ZQ7, Q67YK9, Q682K5, Q9ZT48
      UniProtKB/TrEMBL
      A0A5S9Y214, A0A654FYL6
      Conserved Domains (2) summary
      pfam04376
      Location:29 → 101
      ATE_N; Arginine-tRNA-protein transferase, N-terminus
      pfam04377
      Location:328 → 470
      ATE_C; Arginine-tRNA-protein transferase, C-terminus

    2. NM_001342833.1 → NP_001331417.1  arginine-tRNA protein transferase 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BDT6, A0A654FYL6
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZT48.2

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