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    IPK2a inositol polyphosphate kinase 2 alpha [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830628, updated on 18-Sep-2024

    Summary

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    Official Symbol
    IPK2a
    Official Full Name
    inositol polyphosphate kinase 2 alpha
    Primary source
    TAIR:AT5G07370
    Locus tag
    AT5G07370
    See related
    Araport:AT5G07370
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATIPK2A; IMPK; inositol multi-phosphate kinase; inositol polyphosphate kinase 2 alpha; INOSITOL POLYPHOSPHATE KINASE 2 ALPHA; T2I1.80; T2I1_80
    Summary
    Encodes inositol polyphosphate kinase, which phosphorylates inositol 1,4,5-triphosphate and inositol 1,3,4,5-tetrakisphosphate to generate inositol 1,3,4,5,6-pentakisphosphate
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    Genomic context

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    See IPK2a in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    4
    Sequence:
    Chromosome: 5; NC_003076.8 (2330338..2332338)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Calreticulin family protein Neighboring gene TUDOR-SN protein 1 Neighboring gene Amidase family protein Neighboring gene uncharacterized protein Neighboring gene respiratory burst oxidase homolog A Neighboring gene forkhead-associated domain-containing protein / FHA domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A role of Arabidopsis inositol polyphosphate kinase, AtIPK2alpha, in pollen germination and root growth. Xu J, et al. Plant Physiol, 2005 Jan. PMID 15618435, Free PMC Article
    2. Enzyme activities of Arabidopsis inositol polyphosphate kinases AtIPK2α and AtIPK2β are involved in pollen development, pollen tube guidance and embryogenesis. Zhan H, et al. Plant J, 2015 Jun. PMID 25846941
    3. Molecular and biochemical characterization of two plant inositol polyphosphate 6-/3-/5-kinases. Stevenson-Paulik J, et al. J Biol Chem, 2002 Nov 8. PMID 12226109
    4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The physiological function of an A. thaliana gene encoding inositol polyphosphate kinase in pollen germination and root growth.[AtIPK2alpha]
      Title: A role of Arabidopsis inositol polyphosphate kinase, AtIPK2alpha, in pollen germination and root growth.
    2. AtIPK2alpha and AtIPK2beta are involved in pollen development, pollen tube guidance and embryogenesis.
      Title: Enzyme activities of Arabidopsis inositol polyphosphate kinases AtIPK2α and AtIPK2β are involved in pollen development, pollen tube guidance and embryogenesis.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    NM_120819.2
    NM_180455.3
    NM_180456.2
    NM_203019.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables inositol-1,2,3,4,6-pentakisphosphate 5-kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables inositol-1,3,4,6-tetrakisphosphate 5-kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables inositol-1,4,5,6-tetrakisphosphate 3-kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables inositol-1,4,5-trisphosphate 6-kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within embryo development ending in seed dormancy IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in inositol phosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within pollen development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within pollen germination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within pollen tube growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within pollen tube guidance IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in pollen tube IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    inositol polyphosphate kinase 2 alpha
    NP_196354.1
    • inositol polyphosphate kinase 2 alpha (IPK2a); CONTAINS InterPro DOMAIN/s: Inositol polyphosphate kinase (InterPro:IPR005522); BEST Arabidopsis thaliana protein match is: inositol polyphosphate kinase 2 beta (TAIR:AT5G61760.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
    NP_850786.1
    • inositol polyphosphate kinase 2 alpha (IPK2a); CONTAINS InterPro DOMAIN/s: Inositol polyphosphate kinase (InterPro:IPR005522); BEST Arabidopsis thaliana protein match is: inositol polyphosphate kinase 2 beta (TAIR:AT5G61760.1); Has 805 Blast hits to 803 proteins in 203 species: Archae - 0; Bacteria - 0; Metazoa - 392; Fungi - 227; Plants - 74; Viruses - 0; Other Eukaryotes - 112 (source: NCBI BLink).
    NP_850787.1
    • inositol polyphosphate kinase 2 alpha (IPK2a); CONTAINS InterPro DOMAIN/s: Inositol polyphosphate kinase (InterPro:IPR005522); BEST Arabidopsis thaliana protein match is: inositol polyphosphate kinase 2 beta (TAIR:AT5G61760.1); Has 805 Blast hits to 803 proteins in 203 species: Archae - 0; Bacteria - 0; Metazoa - 392; Fungi - 227; Plants - 74; Viruses - 0; Other Eukaryotes - 112 (source: NCBI BLink).
    NP_974748.1
    • inositol polyphosphate kinase 2 alpha (IPK2a); CONTAINS InterPro DOMAIN/s: Inositol polyphosphate kinase (InterPro:IPR005522); BEST Arabidopsis thaliana protein match is: inositol polyphosphate kinase 2 beta (TAIR:AT5G61760.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      2330338..2332338
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_180455.3 → NP_850786.1  inositol polyphosphate kinase 2 alpha [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850786.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LBG7, Q9LF72, Q9LY23
      UniProtKB/TrEMBL
      A0A178UF38, A0A384LG67, A0A7G2FD12, B9DGE0
      Conserved Domains (1) summary
      PLN02667
      Location:2 → 286
      PLN02667; inositol polyphosphate multikinase

    2. NM_203019.2 → NP_974748.1  inositol polyphosphate kinase 2 alpha [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974748.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LBG7, Q9LF72, Q9LY23
      UniProtKB/TrEMBL
      A0A178UF38, A0A384LG67, A0A7G2FD12, B9DGE0
      Conserved Domains (1) summary
      PLN02667
      Location:2 → 286
      PLN02667; inositol polyphosphate multikinase

    3. NM_180456.2 → NP_850787.1  inositol polyphosphate kinase 2 alpha [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850787.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LBG7, Q9LF72, Q9LY23
      UniProtKB/TrEMBL
      A0A178UF38, A0A384LG67, A0A7G2FD12, B9DGE0
      Conserved Domains (1) summary
      PLN02667
      Location:2 → 286
      PLN02667; inositol polyphosphate multikinase

    4. NM_120819.2 → NP_196354.1  inositol polyphosphate kinase 2 alpha [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_196354.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LBG7, Q9LF72, Q9LY23
      UniProtKB/TrEMBL
      A0A178UF38, A0A384LG67, A0A7G2FD12, B9DGE0
      Conserved Domains (1) summary
      PLN02667
      Location:2 → 286
      PLN02667; inositol polyphosphate multikinase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LY23.1

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