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    NRPB4 RNA polymerase II, Rpb4, core protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830853, updated on 18-Sep-2024

    Summary

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    Official Symbol
    NRPB4
    Official Full Name
    RNA polymerase II, Rpb4, core protein
    Primary source
    TAIR:AT5G09920
    Locus tag
    AT5G09920
    See related
    Araport:AT5G09920
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATRPB15.9; MYH9.13; MYH9_13; RNA POLYMERASE II 15.9 KDA SUBUNIT; RPB15.9; RPB15.9.9
    Summary
    Non-catalytic subunit specific to DNA-dependent RNA polymerase II; the ortholog of budding yeast RPB4)
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    Genomic context

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    See NRPB4 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    6
    Sequence:
    Chromosome: 5; NC_003076.8 (3096183..3097837)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene 26S proteasome regulatory subunit, putative (RPN5) Neighboring gene Ras-related small GTP-binding family protein Neighboring gene ncRNA Neighboring gene ABC transporter family protein Neighboring gene hypothetical protein (DUF1635) Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Two small subunits in Arabidopsis RNA polymerase II are related to yeast RPB4 and RPB7 and interact with one another. Larkin RM, et al. J Biol Chem, 1998 Mar 6. PMID 9488692
    2. Arabidopsis DPB3-1, a DREB2A interactor, specifically enhances heat stress-induced gene expression by forming a heat stress-specific transcriptional complex with NF-Y subunits. Sato H, et al. Plant Cell, 2014 Dec. PMID 25490919, Free PMC Article
    3. Subunit compositions of the RNA-silencing enzymes Pol IV and Pol V reveal their origins as specialized forms of RNA polymerase II. Ream TS, et al. Mol Cell, 2009 Jan 30. PMID 19110459, Free PMC Article
    4. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
    5. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_121029.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-directed 5'-3' RNA polymerase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA-templated transcription initiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within transcription by RNA polymerase II TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of RNA polymerase II, core complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    RNA polymerase II, Rpb4, core protein
    NP_196554.1
    • NRPB4; CONTAINS InterPro DOMAIN/s: HRDC-like (InterPro:IPR010997), RNA polymerase II, Rpb4 (InterPro:IPR005574), RNA polymerase II, Rpb4, core (InterPro:IPR006590); BEST Arabidopsis thaliana protein match is: RNA polymerase II, Rpb4, core protein (TAIR:AT4G15950.1); Has 441 Blast hits to 441 proteins in 181 species: Archae - 4; Bacteria - 0; Metazoa - 144; Fungi - 150; Plants - 95; Viruses - 0; Other Eukaryotes - 48 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      3096183..3097837
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_121029.3 → NP_196554.1  RNA polymerase II, Rpb4, core protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_196554.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O48890
      UniProtKB/TrEMBL
      A0A178UIQ5, A0A5S9Y3E5
      Conserved Domains (1) summary
      smart00657
      Location:16 → 138
      RPOL4c; DNA-directed RNA-polymerase II subunit
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O48890.1

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