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    PRE1 basic helix-loop-helix (bHLH) DNA-binding family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 833982, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PRE1
    Official Full Name
    basic helix-loop-helix (bHLH) DNA-binding family protein
    Primary source
    TAIR:AT5G39860
    Locus tag
    AT5G39860
    See related
    Araport:AT5G39860
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    BANQUO 1; BASIC HELIX-LOOP-HELIX PROTEIN 136; BHLH136; BNQ1; MYH19.1; MYH19_1; PACLOBUTRAZOL RESISTANCE1; PACLOBUTRAZOL RESISTANCE1
    Summary
    Encodes PRE1 (PACLOBUTRAZOL RESISTANCE1). PRE1 and IBH1 form a pair of antagonistic HLH/bHLH transcription factors that function downstream of BZR1 to mediate brassinosteroid regulation of cell elongation. BNQ1 is directly and negatively regulated by AP3 and PI in petals.Required for appropriate regulation of flowering time.
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    Genomic context

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    See PRE1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    2
    Sequence:
    Chromosome: 5; NC_003076.8 (15957368..15958559)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ATP-dependent RNA helicase Neighboring gene Ribosomal protein S4 Neighboring gene miscRNA Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Overexpression of PRE1 and its homologous genes activates Gibberellin-dependent responses in Arabidopsis thaliana. Lee S, et al. Plant Cell Physiol, 2006 May. PMID 16527868
    2. ERECTA signaling controls Arabidopsis inflorescence architecture through chromatin-mediated activation of PRE1 expression. Cai H, et al. New Phytol, 2017 Jun. PMID 28295392
    3. Antagonistic HLH/bHLH transcription factors mediate brassinosteroid regulation of cell elongation and plant development in rice and Arabidopsis. Zhang LY, et al. Plant Cell, 2009 Dec. PMID 20009022, Free PMC Article
    4. A triantagonistic basic helix-loop-helix system regulates cell elongation in Arabidopsis. Ikeda M, et al. Plant Cell, 2012 Nov. PMID 23161888, Free PMC Article
    5. Interactions between HLH and bHLH factors modulate light-regulated plant development. Hao Y, et al. Mol Plant, 2012 May. PMID 22331621, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. PRE1 gene expression is controlled by ERECTA signaling through chromatin remodeling.
      Title: ERECTA signaling controls Arabidopsis inflorescence architecture through chromatin-mediated activation of PRE1 expression.
    2. The expression of IBH1 and PRE1 is regulated by brassinosteroid, gibberellins, and developmental phase dependent factors, indicating that two phytohormones and phase-dependent signals are integrated by this triantagonistic bHLH system.
      Title: A triantagonistic basic helix-loop-helix system regulates cell elongation in Arabidopsis.
    3. PAR1-PRE1 and PAR1-PIF4 heterodimers form a complex HLH/bHLH network regulating cell elongation and plant development in response to light and hormones.
      Title: Interactions between HLH and bHLH factors modulate light-regulated plant development.
    4. PRE1-At IBH1 is a conserved pair of antagonistic HLH/bHLH transcription factors that function downstream of BZR1 to mediate brassinosteroid regulation of cell elongation.
      Title: Antagonistic HLH/bHLH transcription factors mediate brassinosteroid regulation of cell elongation and plant development in rice and Arabidopsis.
    5. PRE genes may have a regulatory role in gibberellin-dependent development in Arabidopsis thaliana [PRE1].
      Title: Overexpression of PRE1 and its homologous genes activates Gibberellin-dependent responses in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_123349.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within photomorphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of growth IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of timing of transition from vegetative to reproductive phase IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to brassinosteroid IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within unidimensional cell growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    basic helix-loop-helix (bHLH) DNA-binding family protein
    NP_198802.1
    • PACLOBUTRAZOL RESISTANCE1 (PRE1); FUNCTIONS IN: DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: response to brassinosteroid stimulus, unidimensional cell growth, photomorphogenesis, regulation of timing of transition from vegetative to reproductive phase; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Helix-loop-helix DNA-binding domain (InterPro:IPR001092); BEST Arabidopsis thaliana protein match is: basic helix-loop-helix (bHLH) DNA-binding family protein (TAIR:AT3G28857.1); Has 97 Blast hits to 97 proteins in 12 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 97; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      15957368..15958559
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_123349.3 → NP_198802.1  basic helix-loop-helix (bHLH) DNA-binding family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_198802.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FLE9
      UniProtKB/TrEMBL
      A0A178UFD8, A0A5S9Y9E3
      Conserved Domains (1) summary
      PLN03217
      Location:14 → 91
      PLN03217; transcription factor ATBS1; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FLE9.1

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