U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    TGA1 bZIP transcription factor family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836646, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    TGA1
    Official Full Name
    bZIP transcription factor family protein
    Primary source
    TAIR:AT5G65210
    Locus tag
    AT5G65210
    See related
    Araport:AT5G65210
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MQN23.15; MQN23_15; TGACG sequence-specific binding protein 1
    Summary
    Encodes TGA1, a redox-controlled regulator of systemic acquired resistance. TGA1 targets the activation sequence-1 (as-1) element of the promoter region of defense proteins. TGA1 are S-nitrosylated.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See TGA1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    10
    Sequence:
    Chromosome: 5; NC_003076.8 (26057533..26061157)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene NAD(P)-binding Rossmann-fold superfamily protein Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene Ribosomal L29 family protein Neighboring gene uncharacterized protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. TGA1 and G-box binding factors: two distinct classes of Arabidopsis leucine zipper proteins compete for the G-box-like element TGACGTGG. Schindler U, et al. Plant Cell, 1992 Oct. PMID 1446171, Free PMC Article
    2. Redox-active cysteines in TGACG-BINDING FACTOR 1 (TGA1) do not play a role in salicylic acid or pathogen-induced expression of TGA1-regulated target genes in Arabidopsis thaliana. Budimir J, et al. New Phytol, 2021 Jun. PMID 32315441
    3. Brassinosteroids enhance salicylic acid-mediated immune responses by inhibiting BIN2 phosphorylation of clade I TGA transcription factors in Arabidopsis. Kim YW, et al. Mol Plant, 2022 Jun 6. PMID 35524409
    4. TGACG-BINDING FACTOR 1 (TGA1) and TGA4 regulate salicylic acid and pipecolic acid biosynthesis by modulating the expression of SYSTEMIC ACQUIRED RESISTANCE DEFICIENT 1 (SARD1) and CALMODULIN-BINDING PROTEIN 60g (CBP60g). Sun T, et al. New Phytol, 2018 Jan. PMID 28898429
    5. Redox regulation of the NPR1-TGA1 system of Arabidopsis thaliana by nitric oxide. Lindermayr C, et al. Plant Cell, 2010 Aug. PMID 20716698, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Redox-active cysteines in TGACG-BINDING FACTOR 1 (TGA1) do not play a role in salicylic acid or pathogen-induced expression of TGA1-regulated target genes in Arabidopsis thaliana.
      Title: Redox-active cysteines in TGACG-BINDING FACTOR 1 (TGA1) do not play a role in salicylic acid or pathogen-induced expression of TGA1-regulated target genes in Arabidopsis thaliana.
    2. Clade I TGACG-Motif Binding Basic Leucine Zipper Transcription Factors Mediate BLADE-ON-PETIOLE-Dependent Regulation of Development.
      Title: Clade I TGACG-Motif Binding Basic Leucine Zipper Transcription Factors Mediate BLADE-ON-PETIOLE-Dependent Regulation of Development.
    3. Our study showed that TGA1 and TGA4 regulate Pip and SA biosynthesis by modulating the expression of SARD1 and CBP60g.
      Title: TGACG-BINDING FACTOR 1 (TGA1) and TGA4 regulate salicylic acid and pipecolic acid biosynthesis by modulating the expression of SYSTEMIC ACQUIRED RESISTANCE DEFICIENT 1 (SARD1) and CALMODULIN-BINDING PROTEIN 60g (CBP60g).
    4. TGA1 and TGA4 as important regulatory factors of the nitrate response in Arabidopsis roots.
      Title: Systems approach identifies TGA1 and TGA4 transcription factors as important regulatory components of the nitrate response of Arabidopsis thaliana roots.
    5. clade I TGA factors as positive regulators of one or more ER-related secretion pathways
      Title: Arabidopsis clade I TGA factors regulate apoplastic defences against the bacterial pathogen Pseudomonas syringae through endoplasmic reticulum-based processes.
    6. S-nitrosoglutathione enhances the DNA binding activity of TGA1 in presence of NPR1 and that both proteins, NPR1 and TGA1, are S-nitrosylated after treatment with the NO donor.
      Title: Redox regulation of the NPR1-TGA1 system of Arabidopsis thaliana by nitric oxide.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help
    NM_001037070.1
    NM_001037071.1
    NM_001037072.2
    NM_001085331.1
    NM_001345675.1
    NM_125919.3
    NM_180942.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA binding TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within defense response to bacterium IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    bZIP transcription factor family protein
    NP_001032147.1
    • TGA1; CONTAINS InterPro DOMAIN/s: Basic-leucine zipper (bZIP) transcription factor (InterPro:IPR004827), bZIP transcription factor, bZIP-1 (InterPro:IPR011616); BEST Arabidopsis thaliana protein match is: TGACG motif-binding factor 4 (TAIR:AT5G10030.2); Has 731 Blast hits to 729 proteins in 53 species: Archae - 0; Bacteria - 0; Metazoa - 7; Fungi - 0; Plants - 693; Viruses - 0; Other Eukaryotes - 31 (source: NCBI BLink).
    NP_001032149.1
    • TGA1; CONTAINS InterPro DOMAIN/s: Basic-leucine zipper (bZIP) transcription factor (InterPro:IPR004827), bZIP transcription factor, bZIP-1 (InterPro:IPR011616); BEST Arabidopsis thaliana protein match is: TGACG motif-binding factor 4 (TAIR:AT5G10030.2); Has 731 Blast hits to 729 proteins in 53 species: Archae - 0; Bacteria - 0; Metazoa - 7; Fungi - 0; Plants - 693; Viruses - 0; Other Eukaryotes - 31 (source: NCBI BLink).
    NP_001078800.1
    • TGA1; CONTAINS InterPro DOMAIN/s: Basic-leucine zipper (bZIP) transcription factor (InterPro:IPR004827), bZIP transcription factor, bZIP-1 (InterPro:IPR011616); BEST Arabidopsis thaliana protein match is: TGACG motif-binding factor 4 (TAIR:AT5G10030.2); Has 674 Blast hits to 672 proteins in 50 species: Archae - 0; Bacteria - 0; Metazoa - 2; Fungi - 0; Plants - 649; Viruses - 0; Other Eukaryotes - 23 (source: NCBI BLink).
    NP_001318881.1
    • TGA1; CONTAINS InterPro DOMAIN/s: Basic-leucine zipper (bZIP) transcription factor (InterPro:IPR004827), bZIP transcription factor, bZIP-1 (InterPro:IPR011616); BEST Arabidopsis thaliana protein match is: TGACG motif-binding factor 4 (TAIR:AT5G10030.2); Has 731 Blast hits to 729 proteins in 53 species: Archae - 0; Bacteria - 0; Metazoa - 7; Fungi - 0; Plants - 693; Viruses - 0; Other Eukaryotes - 31 (source: NCBI BLink).
    NP_201324.1
    • TGA1; CONTAINS InterPro DOMAIN/s: Basic-leucine zipper (bZIP) transcription factor (InterPro:IPR004827), bZIP transcription factor, bZIP-1 (InterPro:IPR011616); BEST Arabidopsis thaliana protein match is: TGACG motif-binding factor 4 (TAIR:AT5G10030.2); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
    NP_851273.1
    • TGA1; CONTAINS InterPro DOMAIN/s: Basic-leucine zipper (bZIP) transcription factor (InterPro:IPR004827), bZIP transcription factor, bZIP-1 (InterPro:IPR011616); BEST Arabidopsis thaliana protein match is: TGACG motif-binding factor 4 (TAIR:AT5G10030.2); Has 731 Blast hits to 729 proteins in 53 species: Archae - 0; Bacteria - 0; Metazoa - 7; Fungi - 0; Plants - 693; Viruses - 0; Other Eukaryotes - 31 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      26057533..26061157
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_180942.3 → NP_851273.1  bZIP transcription factor family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_851273.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q39237, Q8LBQ9, Q9FJP4
      UniProtKB/TrEMBL
      A0A178UQV2, A0A384L8H7, B9DGG1, B9DHB5
      Conserved Domains (2) summary
      cd14708
      Location:84 → 135
      bZIP_HBP1b-like; Basic leucine zipper (bZIP) domain of uncharaterized BZIP transcription factors with similarity to Triticum aestivum HBP-1b: a DNA-binding and dimerization domain
      pfam14144
      Location:170 → 244
      DOG1; Seed dormancy control

    2. NM_001085331.1 → NP_001078800.1  bZIP transcription factor family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001078800.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8MQK5, B9DHB5
      Conserved Domains (3) summary
      cd14686
      Location:15 → 65
      bZIP; coiled coil [structural motif]
      pfam14144
      Location:100 → 176
      DOG1; Seed dormancy control
      cl21462
      Location:14 → 65
      bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain

    3. NM_001037072.2 → NP_001032149.1  bZIP transcription factor family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001032149.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q39237, Q8LBQ9, Q9FJP4
      UniProtKB/TrEMBL
      A0A178UQV2, A0A384L8H7, B9DGG1, B9DHB5
      Conserved Domains (2) summary
      cd14708
      Location:84 → 135
      bZIP_HBP1b-like; Basic leucine zipper (bZIP) domain of uncharaterized BZIP transcription factors with similarity to Triticum aestivum HBP-1b: a DNA-binding and dimerization domain
      pfam14144
      Location:170 → 244
      DOG1; Seed dormancy control

    4. NM_001037070.1 → NP_001032147.1  bZIP transcription factor family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001032147.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q39237, Q8LBQ9, Q9FJP4
      UniProtKB/TrEMBL
      A0A178UQV2, A0A384L8H7, B9DGG1, B9DHB5
      Conserved Domains (2) summary
      cd14708
      Location:84 → 135
      bZIP_HBP1b-like; Basic leucine zipper (bZIP) domain of uncharaterized BZIP transcription factors with similarity to Triticum aestivum HBP-1b: a DNA-binding and dimerization domain
      pfam14144
      Location:170 → 244
      DOG1; Seed dormancy control

    5. NM_001345675.1 → NP_001318881.1  bZIP transcription factor family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q39237, Q8LBQ9, Q9FJP4
      UniProtKB/TrEMBL
      A0A178UQV2, A0A384L8H7, B9DGG1, B9DHB5
      Conserved Domains (2) summary
      cd14708
      Location:84 → 135
      bZIP_HBP1b-like; Basic leucine zipper (bZIP) domain of uncharaterized BZIP transcription factors with similarity to Triticum aestivum HBP-1b: a DNA-binding and dimerization domain
      pfam14144
      Location:170 → 244
      DOG1; Seed dormancy control

    6. NM_125919.3 → NP_201324.1  bZIP transcription factor family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_201324.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q39237, Q8LBQ9, Q9FJP4
      UniProtKB/TrEMBL
      A0A178UQV2, A0A384L8H7, B9DGG1, B9DHB5
      Conserved Domains (2) summary
      cd14708
      Location:84 → 135
      bZIP_HBP1b-like; Basic leucine zipper (bZIP) domain of uncharaterized BZIP transcription factors with similarity to Triticum aestivum HBP-1b: a DNA-binding and dimerization domain
      pfam14144
      Location:170 → 244
      DOG1; Seed dormancy control

    7. NM_001037071.1 → NP_001032148.1  bZIP transcription factor family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001032148.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q39237, Q8LBQ9, Q9FJP4
      UniProtKB/TrEMBL
      A0A178UQV2, A0A384L8H7, B9DGG1, B9DHB5
      Conserved Domains (2) summary
      cd14708
      Location:84 → 135
      bZIP_HBP1b-like; Basic leucine zipper (bZIP) domain of uncharaterized BZIP transcription factors with similarity to Triticum aestivum HBP-1b: a DNA-binding and dimerization domain
      pfam14144
      Location:170 → 244
      DOG1; Seed dormancy control
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q39237.2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools