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    Atrx ATRX, chromatin remodeler [ Rattus norvegicus (Norway rat) ]

    Gene ID: 246284, updated on 3-Dec-2024

    Summary

    Symbol
    Atrxprovided by RGD
    Full Name
    ATRX, chromatin remodelerprovided by RGD
    Primary source
    RGD:619795
    See related
    EnsemblRapid:ENSRNOG00000056703 AllianceGenome:RGD:619795
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Xnp
    Summary
    Predicted to enable several functions, including DNA translocase activity; chromo shadow domain binding activity; and methylated histone binding activity. Predicted to be involved in several processes, including cellular response to hydroxyurea; chromatin remodeling; and positive regulation of nucleobase-containing compound metabolic process. Predicted to act upstream of or within several processes, including male gonad development; meiotic spindle organization; and post-embryonic forelimb morphogenesis. Predicted to be located in chromosomal region and nuclear lumen. Human ortholog(s) of this gene implicated in X-linked mental retardation-hypotonic facies syndrome-1; alpha thalassemia-X-linked intellectual disability syndrome; alpha-thalassemia myelodysplasia syndrome; high grade glioma; and lung small cell carcinoma. Orthologous to human ATRX (ATRX chromatin remodeler). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Thymus (RPKM 224.2), Brain (RPKM 211.0) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Atrx in Genome Data Viewer
    Location:
    Xq22
    Exon count:
    40
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (74916548..75062880, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (70850981..70997330, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (76820110..76979155, complement)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene Glyceraldehyde-3-phosphate dehydrogenase, pseudogene 6 Neighboring gene transfer RNA glycine (anticodon ACC) 8 Neighboring gene fibroblast growth factor 16 Neighboring gene U2 spliceosomal RNA Neighboring gene uncharacterized LOC134484000 Neighboring gene GC-rich promoter binding protein 1, pseudogene 1 Neighboring gene magnesium transporter 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP-dependent H2AZ histone chaperone activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP-dependent H3-H4 histone complex chaperone activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA clamp loader activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA translocase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA translocase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables chromatin binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables chromatin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables chromatin binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables chromatin extrusion motor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables chromo shadow domain binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables chromo shadow domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables cohesin loader activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables double-stranded DNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables forked DNA-dependent helicase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables four-way junction helicase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables helicase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables histone binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables methylated histone binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables methylated histone binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables single-stranded 3'-5' DNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in DNA damage response, signal transduction by p53 class mediator IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in DNA damage response, signal transduction by p53 class mediator ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in DNA damage response, signal transduction by p53 class mediator ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in DNA duplex unwinding IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in DNA repair IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in Sertoli cell development IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within Sertoli cell development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in cellular response to hydroxyurea IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cellular response to hydroxyurea ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cellular response to hydroxyurea ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in chromatin looping IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in chromatin organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in chromatin organization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in chromatin remodeling ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in chromatin remodeling ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in chromosome organization involved in meiotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within chromosome organization involved in meiotic cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in forebrain development IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within forebrain development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in meiotic spindle organization IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within meiotic spindle organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in multicellular organism growth IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within multicellular organism growth ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of macromolecule biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in nucleosome assembly IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in nucleosome assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in nucleosome assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of nuclear cell cycle DNA replication IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of nuclear cell cycle DNA replication ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of nuclear cell cycle DNA replication ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of telomere maintenance IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of telomere maintenance ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of telomere maintenance ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of transcription by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in post-embryonic forelimb morphogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within post-embryonic forelimb morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein localization to chromosome, telomeric region IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein localization to chromosome, telomeric region ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of gene expression IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in replication fork processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in replication fork processing ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in replication fork processing ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in seminiferous tubule development IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within seminiferous tubule development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in spermatogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within spermatogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in subtelomeric heterochromatin formation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in subtelomeric heterochromatin formation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in subtelomeric heterochromatin formation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in PML body IEA
    Inferred from Electronic Annotation
    more info
     
    located_in PML body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in chromosome, subtelomeric region IEA
    Inferred from Electronic Annotation
    more info
     
    located_in chromosome, subtelomeric region ISO
    Inferred from Sequence Orthology
    more info
     
    located_in chromosome, telomeric region IEA
    Inferred from Electronic Annotation
    more info
     
    located_in chromosome, telomeric region ISO
    Inferred from Sequence Orthology
    more info
     
    located_in chromosome, telomeric region ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in condensed chromosome, centromeric region IEA
    Inferred from Electronic Annotation
    more info
     
    located_in condensed chromosome, centromeric region ISO
    Inferred from Sequence Orthology
    more info
     
    located_in heterochromatin ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nuclear chromosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear speck ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in pericentric heterochromatin IEA
    Inferred from Electronic Annotation
    more info
     
    located_in pericentric heterochromatin ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    transcriptional regulator ATRX
    Names
    ATP-dependent helicase ATRX
    X-linked nuclear protein
    helicase II
    pABP-2
    transcriptional regulator ATRX-like
    NP_001099227.2
    XP_038955386.1
    XP_038955387.1
    XP_038955388.1
    XP_038955389.1
    XP_038955390.1
    XP_038955392.1
    XP_038955393.1
    XP_038955394.1
    XP_038955395.1
    XP_038955396.1
    XP_038955397.1
    XP_038955398.1
    XP_038955399.1
    XP_038955400.1
    XP_038955401.1
    XP_038955403.1
    XP_063135850.1
    XP_063135852.1
    XP_063135853.1
    XP_063135854.1
    XP_063135856.1
    XP_063135857.1
    XP_063135858.1
    XP_063135859.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001105757.2NP_001099227.2  transcriptional regulator ATRX

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000021
      UniProtKB/TrEMBL
      A0A0G2JXZ3, A0A8I6GFB1
      Related
      ENSRNOP00000087612.1, ENSRNOT00000091284.3
      Conserved Domains (3) summary
      COG0553
      Location:15132164
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      cd11726
      Location:166269
      ADDz_ATRX; ADDz domain found in ATRX (alpha-thalassemia/mental retardation, X-linked)
      cd18068
      Location:15381781
      DEXHc_ATRX; DEXH-box helicase domain of ATRX

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      74916548..75062880 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063279780.1XP_063135850.1  transcriptional regulator ATRX isoform X3

      UniProtKB/TrEMBL
      A0A0G2JXZ3
    2. XM_039099473.2XP_038955401.1  transcriptional regulator ATRX isoform X10

      UniProtKB/TrEMBL
      A0A0G2JXZ3
      Conserved Domains (3) summary
      COG0553
      Location:14582109
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      cd11726
      Location:111214
      ADDz_ATRX; ADDz domain found in ATRX (alpha-thalassemia/mental retardation, X-linked)
      cd18068
      Location:14831726
      DEXHc_ATRX; DEXH-box helicase domain of ATRX
    3. XM_039099471.2XP_038955399.1  transcriptional regulator ATRX isoform X8

      UniProtKB/TrEMBL
      A0A0G2JXZ3
      Conserved Domains (3) summary
      COG0553
      Location:14742125
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      cd11726
      Location:127230
      ADDz_ATRX; ADDz domain found in ATRX (alpha-thalassemia/mental retardation, X-linked)
      cd18068
      Location:14991742
      DEXHc_ATRX; DEXH-box helicase domain of ATRX
    4. XM_039099462.2XP_038955390.1  transcriptional regulator ATRX isoform X6

      UniProtKB/TrEMBL
      A0A0G2JXZ3, A0A8I6A4N1
      Related
      ENSRNOP00000087702.1, ENSRNOT00000095781.2
      Conserved Domains (3) summary
      COG0553
      Location:14752126
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      cd11726
      Location:128231
      ADDz_ATRX; ADDz domain found in ATRX (alpha-thalassemia/mental retardation, X-linked)
      cd18068
      Location:15001743
      DEXHc_ATRX; DEXH-box helicase domain of ATRX
    5. XM_039099469.2XP_038955397.1  transcriptional regulator ATRX isoform X7

      UniProtKB/TrEMBL
      A0A0G2JXZ3
      Conserved Domains (3) summary
      COG0553
      Location:14742125
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      cd11726
      Location:127230
      ADDz_ATRX; ADDz domain found in ATRX (alpha-thalassemia/mental retardation, X-linked)
      cd18068
      Location:14991742
      DEXHc_ATRX; DEXH-box helicase domain of ATRX
    6. XM_063279786.1XP_063135856.1  transcriptional regulator ATRX isoform X10

      UniProtKB/TrEMBL
      A0A0G2JXZ3
    7. XM_039099470.2XP_038955398.1  transcriptional regulator ATRX isoform X7

      UniProtKB/TrEMBL
      A0A0G2JXZ3
      Conserved Domains (3) summary
      COG0553
      Location:14742125
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      cd11726
      Location:127230
      ADDz_ATRX; ADDz domain found in ATRX (alpha-thalassemia/mental retardation, X-linked)
      cd18068
      Location:14991742
      DEXHc_ATRX; DEXH-box helicase domain of ATRX
    8. XM_039099468.2XP_038955396.1  transcriptional regulator ATRX isoform X7

      UniProtKB/TrEMBL
      A0A0G2JXZ3
      Conserved Domains (3) summary
      COG0553
      Location:14742125
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      cd11726
      Location:127230
      ADDz_ATRX; ADDz domain found in ATRX (alpha-thalassemia/mental retardation, X-linked)
      cd18068
      Location:14991742
      DEXHc_ATRX; DEXH-box helicase domain of ATRX
    9. XM_039099472.2XP_038955400.1  transcriptional regulator ATRX isoform X10

      UniProtKB/TrEMBL
      A0A0G2JXZ3
      Conserved Domains (3) summary
      COG0553
      Location:14582109
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      cd11726
      Location:111214
      ADDz_ATRX; ADDz domain found in ATRX (alpha-thalassemia/mental retardation, X-linked)
      cd18068
      Location:14831726
      DEXHc_ATRX; DEXH-box helicase domain of ATRX
    10. XM_039099464.2XP_038955392.1  transcriptional regulator ATRX isoform X7

      UniProtKB/TrEMBL
      A0A0G2JXZ3
      Conserved Domains (3) summary
      COG0553
      Location:14742125
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      cd11726
      Location:127230
      ADDz_ATRX; ADDz domain found in ATRX (alpha-thalassemia/mental retardation, X-linked)
      cd18068
      Location:14991742
      DEXHc_ATRX; DEXH-box helicase domain of ATRX
    11. XM_039099466.2XP_038955394.1  transcriptional regulator ATRX isoform X7

      UniProtKB/TrEMBL
      A0A0G2JXZ3
      Conserved Domains (3) summary
      COG0553
      Location:14742125
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      cd11726
      Location:127230
      ADDz_ATRX; ADDz domain found in ATRX (alpha-thalassemia/mental retardation, X-linked)
      cd18068
      Location:14991742
      DEXHc_ATRX; DEXH-box helicase domain of ATRX
    12. XM_063279784.1XP_063135854.1  transcriptional regulator ATRX isoform X10

      UniProtKB/TrEMBL
      A0A0G2JXZ3
    13. XM_039099467.2XP_038955395.1  transcriptional regulator ATRX isoform X7

      UniProtKB/TrEMBL
      A0A0G2JXZ3
      Conserved Domains (3) summary
      COG0553
      Location:14742125
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      cd11726
      Location:127230
      ADDz_ATRX; ADDz domain found in ATRX (alpha-thalassemia/mental retardation, X-linked)
      cd18068
      Location:14991742
      DEXHc_ATRX; DEXH-box helicase domain of ATRX
    14. XM_039099465.2XP_038955393.1  transcriptional regulator ATRX isoform X7

      UniProtKB/TrEMBL
      A0A0G2JXZ3
      Conserved Domains (3) summary
      COG0553
      Location:14742125
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      cd11726
      Location:127230
      ADDz_ATRX; ADDz domain found in ATRX (alpha-thalassemia/mental retardation, X-linked)
      cd18068
      Location:14991742
      DEXHc_ATRX; DEXH-box helicase domain of ATRX
    15. XM_063279787.1XP_063135857.1  transcriptional regulator ATRX isoform X11

      UniProtKB/TrEMBL
      A0A0G2JXZ3
    16. XM_063279782.1XP_063135852.1  transcriptional regulator ATRX isoform X7

      UniProtKB/TrEMBL
      A0A0G2JXZ3
      Related
      ENSRNOP00000070457.2, ENSRNOT00000087977.3
    17. XM_063279788.1XP_063135858.1  transcriptional regulator ATRX isoform X12

      UniProtKB/TrEMBL
      A0A0G2JXZ3
    18. XM_063279783.1XP_063135853.1  transcriptional regulator ATRX isoform X9

      UniProtKB/TrEMBL
      A0A0G2JXZ3
    19. XM_039099458.2XP_038955386.1  transcriptional regulator ATRX isoform X1

      UniProtKB/TrEMBL
      A0A0G2JXZ3
      Conserved Domains (3) summary
      COG0553
      Location:15232174
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      cd11726
      Location:176279
      ADDz_ATRX; ADDz domain found in ATRX (alpha-thalassemia/mental retardation, X-linked)
      cd18068
      Location:15481791
      DEXHc_ATRX; DEXH-box helicase domain of ATRX
    20. XM_039099461.2XP_038955389.1  transcriptional regulator ATRX isoform X5

      UniProtKB/TrEMBL
      A0A0G2JXZ3
      Conserved Domains (3) summary
      COG0553
      Location:14842135
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      cd11726
      Location:137240
      ADDz_ATRX; ADDz domain found in ATRX (alpha-thalassemia/mental retardation, X-linked)
      cd18068
      Location:15091752
      DEXHc_ATRX; DEXH-box helicase domain of ATRX
    21. XM_039099460.2XP_038955388.1  transcriptional regulator ATRX isoform X4

      UniProtKB/TrEMBL
      A0A0G2JXZ3
      Conserved Domains (3) summary
      COG0553
      Location:14852136
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      cd11726
      Location:138241
      ADDz_ATRX; ADDz domain found in ATRX (alpha-thalassemia/mental retardation, X-linked)
      cd18068
      Location:15101753
      DEXHc_ATRX; DEXH-box helicase domain of ATRX
    22. XM_039099459.2XP_038955387.1  transcriptional regulator ATRX isoform X2

      UniProtKB/TrEMBL
      A0A0G2JXZ3
      Conserved Domains (3) summary
      COG0553
      Location:15222173
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      cd11726
      Location:175278
      ADDz_ATRX; ADDz domain found in ATRX (alpha-thalassemia/mental retardation, X-linked)
      cd18068
      Location:15471790
      DEXHc_ATRX; DEXH-box helicase domain of ATRX
    23. XM_063279789.1XP_063135859.1  transcriptional regulator ATRX isoform X14

    24. XM_039099475.2XP_038955403.1  transcriptional regulator ATRX isoform X13

      Conserved Domains (2) summary
      cd11726
      Location:176279
      ADDz_ATRX; ADDz domain found in ATRX (alpha-thalassemia/mental retardation, X-linked)
      cd18068
      Location:15481791
      DEXHc_ATRX; DEXH-box helicase domain of ATRX