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    Pop4 processing of precursor 4, ribonuclease P/MRP family, (S. cerevisiae) [ Mus musculus (house mouse) ]

    Gene ID: 66161, updated on 27-Nov-2024

    Summary

    Official Symbol
    Pop4provided by MGI
    Official Full Name
    processing of precursor 4, ribonuclease P/MRP family, (S. cerevisiae)provided by MGI
    Primary source
    MGI:MGI:1913411
    See related
    Ensembl:ENSMUSG00000030423 AllianceGenome:MGI:1913411
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rpp29; 1110023P21Rik
    Summary
    Predicted to enable ribonuclease P RNA binding activity. Predicted to contribute to ribonuclease P activity. Predicted to be involved in rRNA processing and tRNA 5'-leader removal. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of multimeric ribonuclease P complex and ribonuclease MRP complex. Is expressed in sensory organ and skeleton. Orthologous to human POP4 (POP4 homolog, ribonuclease P/MRP subunit). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 23.9), CNS E14 (RPKM 20.3) and 26 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Pop4 in Genome Data Viewer
    Location:
    7 B3; 7 25.36 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (37962239..37970803, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (38262812..38271393, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA D530033B14 gene Neighboring gene RIKEN cDNA 1600014C10 gene Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:38974627-38974780 Neighboring gene STARR-positive B cell enhancer ABC_E3714 Neighboring gene pleckstrin homology domain containing, family F (with FYVE domain) member 1 Neighboring gene STARR-seq mESC enhancer starr_18689 Neighboring gene STARR-seq mESC enhancer starr_18690 Neighboring gene STARR-seq mESC enhancer starr_18693 Neighboring gene predicted gene 9220 Neighboring gene predicted gene 4451

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (1) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ribonuclease P RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ribonuclease P RNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables ribonuclease P RNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    contributes_to ribonuclease P activity ISO
    Inferred from Sequence Orthology
    more info
     
    contributes_to ribonuclease P activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in rRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in tRNA 5'-leader removal ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in tRNA 5'-leader removal ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    part_of multimeric ribonuclease P complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of multimeric ribonuclease P complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    part_of ribonuclease MRP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of ribonuclease MRP complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of ribonuclease P complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    ribonuclease P protein subunit p29
    Names
    POP4 (processing of precursor , S. cerevisiae) homolog
    NP_079666.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025390.5NP_079666.1  ribonuclease P protein subunit p29

      See identical proteins and their annotated locations for NP_079666.1

      Status: VALIDATED

      Source sequence(s)
      AC157552
      Consensus CDS
      CCDS39915.1
      UniProtKB/Swiss-Prot
      Q3U6V7, Q9CR08
      Related
      ENSMUSP00000032585.7, ENSMUST00000032585.8
      Conserved Domains (1) summary
      pfam01868
      Location:129211
      UPF0086; Domain of unknown function UPF0086

    RNA

    1. NR_184804.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC157552
    2. NR_184805.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC157552

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      37962239..37970803 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)