PDIL2-3 PDI-like 2-3 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: PDIL2-3
Official Full Name: PDI-like 2-3
Primary source: TAIR:AT2G32920
Locus tag: AT2G32920
See related: Araport:AT2G32920
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ARABIDOPSIS THALIANA PROTEIN DISULFIDE ISOMERASE 9; ATPDI9; ATPDIL2-3; PDI-like 2-3; PDI9; PROTEIN DISULFIDE ISOMERASE 9; T21L14.14; T21L14_14
Summary: Encodes a protein disulfide isomerase-like (PDIL) protein, a member of a multigene family within the thioredoxin (TRX) superfamily. Transcript levels for this gene are up-regulated in response to three different chemical inducers of ER stress (dithiothreitol, beta-mercaptoethanol, and tunicamycin). AtIRE1-2 does not appear to be required for this response, but the atbzip60 mutant has a diminished response.
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Chromosome 2 - NC_003071.7 Genomic Context describing neighboring genes

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NM_128852.5

Function	Evidence Code	Pubs
enables protein disulfide isomerase activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within response to endoplasmic reticulum stress	IEP Inferred from Expression Pattern more info	PubMed

Component	Evidence Code	Pubs
located_in Golgi apparatus	HDA more info	PubMed
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in endoplasmic reticulum	HDA more info	PubMed
located_in plant-type vacuole	HDA more info	PubMed

NP_180851.1

PDI-like 2-3 (PDIL2-3); FUNCTIONS IN: protein disulfide isomerase activity; INVOLVED IN: response to endoplasmic reticulum stress; LOCATED IN: endoplasmic reticulum, plasma membrane, vacuole; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Disulphide isomerase (InterPro:IPR005788), Thioredoxin domain (InterPro:IPR013766), Thioredoxin, conserved site (InterPro:IPR017937), Thioredoxin-like subdomain (InterPro:IPR006662), Thioredoxin-like (InterPro:IPR017936), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: PDI-like 2-2 (TAIR:AT1G04980.1); Has 34824 Blast hits to 18409 proteins in 2879 species: Archae - 382; Bacteria - 17291; Metazoa - 5423; Fungi - 1895; Plants - 2648; Viruses - 40; Other Eukaryotes - 7145 (source: NCBI BLink).

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The following sections contain reference sequences that belong to a specific genome build. Explain