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    MEE23 FAD-binding Berberine family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818044, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MEE23
    Official Full Name
    FAD-binding Berberine family protein
    Primary source
    TAIR:AT2G34790
    Locus tag
    AT2G34790
    See related
    Araport:AT2G34790
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    EDA28; EMBRYO SAC DEVELOPMENT ARREST 28; F19I3.2; F19I3_2; MATERNAL EFFECT EMBRYO ARREST 23
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    Genomic context

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    See MEE23 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    3
    Sequence:
    Chromosome: 2; NC_003071.7 (14673840..14677398, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene ncRNA Neighboring gene fatty acid hydroxylase 1 Neighboring gene maternal effect embryo arrest 22 Neighboring gene ncRNA Neighboring gene FAD-binding Berberine family protein Neighboring gene basic helix-loop-helix (bHLH) DNA-binding superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The catalytic machinery of the FAD-dependent AtBBE-like protein 15 for alcohol oxidation: Y193 and Y479 form a catalytic base, Q438 and R292 an alkoxide binding site. Messenlehner J, et al. Arch Biochem Biophys, 2021 Mar 30. PMID 33485849
    2. Oxidation of Monolignols by Members of the Berberine Bridge Enzyme Family Suggests a Role in Plant Cell Wall Metabolism. Daniel B, et al. J Biol Chem, 2015 Jul 24. PMID 26037923, Free PMC Article
    3. Proteomics of loosely bound cell wall proteins of Arabidopsis thaliana cell suspension cultures: a critical analysis. Borderies G, et al. Electrophoresis, 2003 Oct. PMID 14595688
    4. Cell wall proteins in apoplastic fluids of Arabidopsis thaliana rosettes: identification by mass spectrometry and bioinformatics. Boudart G, et al. Proteomics, 2005 Jan. PMID 15593128
    5. Genetic and molecular identification of genes required for female gametophyte development and function in Arabidopsis. Pagnussat GC, et al. Development, 2005 Feb. PMID 15634699

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The catalytic machinery of the FAD-dependent AtBBE-like protein 15 for alcohol oxidation: Y193 and Y479 form a catalytic base, Q438 and R292 an alkoxide binding site.
      Title: The catalytic machinery of the FAD-dependent AtBBE-like protein 15 for alcohol oxidation: Y193 and Y479 form a catalytic base, Q438 and R292 an alkoxide binding site.
    2. berberine bridge enzyme (BBE)-like enzymes catalyze the oxidation of aromatic allylic alcohols, such as coumaryl, sinapyl, and coniferyl alcohol, to the corresponding aldehydes and that AtBBE-like 15 adopts the same fold as vanillyl alcohol oxidase as reported previously for berberine bridge enzyme and other FAD-dependent oxidoreductases. [ATBBE-LIKE 15]
      Title: Oxidation of Monolignols by Members of the Berberine Bridge Enzyme Family Suggests a Role in Plant Cell Wall Metabolism.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    NM_129032.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables FAD binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cinnamyl-alcohol dehydrogenase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables cinnamyl-alcohol dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables coniferyl-alcohol dehydrogenase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within embryo development ending in seed dormancy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within polar nucleus fusion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plant-type cell wall HDA PubMed 
    located_in plant-type cell wall IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasmodesma HDA PubMed 

    General protein information

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    Preferred Names
    FAD-binding Berberine family protein
    NP_181025.1
    • MATERNAL EFFECT EMBRYO ARREST 23 (MEE23); FUNCTIONS IN: electron carrier activity, oxidoreductase activity, FAD binding, catalytic activity; INVOLVED IN: polar nucleus fusion, embryo development ending in seed dormancy; LOCATED IN: cell wall; EXPRESSED IN: 13 plant structures; EXPRESSED DURING: 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: FAD-binding, type 2 (InterPro:IPR016166), Berberine/berberine-like (InterPro:IPR012951), FAD linked oxidase, N-terminal (InterPro:IPR006094); BEST Arabidopsis thaliana protein match is: FAD-binding Berberine family protein (TAIR:AT1G30760.1); Has 4988 Blast hits to 4831 proteins in 776 species: Archae - 82; Bacteria - 2407; Metazoa - 5; Fungi - 1644; Plants - 646; Viruses - 0; Other Eukaryotes - 204 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      14673840..14677398 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_129032.5 → NP_181025.1  FAD-binding Berberine family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_181025.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O64743
      UniProtKB/TrEMBL
      A0A178VZ42, A0A5S9X443, A0A654EYW3
      Conserved Domains (2) summary
      COG0277
      Location:94 → 530
      GlcD; FAD/FMN-containing dehydrogenase [Energy production and conversion]
      pfam01565
      Location:82 → 221
      FAD_binding_4; FAD binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O64743.1

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