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    CRK1 CDPK-related kinase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818713, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CRK1
    Official Full Name
    CDPK-related kinase 1
    Primary source
    TAIR:AT2G41140
    Locus tag
    AT2G41140
    See related
    Araport:AT2G41140
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATCBK3; ATCRK1; CDPK-related kinase 1; T3K9.9; T3K9_9
    Summary
    Encodes CDPK-related kinase 1 (CRK1).
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    Genomic context

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    See CRK1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    11
    Sequence:
    Chromosome: 2; NC_003071.7 (17150095..17153693)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene DUF309 domain protein Neighboring gene ncRNA Neighboring gene basic helix-loop-helix (bHLH) DNA-binding superfamily protein Neighboring gene ncRNA Neighboring gene plant/protein Neighboring gene Ubiquitin-associated (UBA) protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional Analysis of the Arabidopsis thaliana CDPK-Related Kinase Family: AtCRK1 Regulates Responses to Continuous Light. Baba AI, et al. Int J Mol Sci, 2018 Apr 25. PMID 29693594, Free PMC Article
    2. Characterization of a calmodulin-regulated Ca2+-dependent-protein-kinase-related protein kinase, AtCRK1, from Arabidopsis. Wang Y, et al. Biochem J, 2004 Oct 1. PMID 15196054, Free PMC Article
    3. The calmodulin-binding protein kinase 3 is part of heat-shock signal transduction in Arabidopsis thaliana. Liu HT, et al. Plant J, 2008 Sep. PMID 18466301
    4. Evidence for intermolecular interactions between the intracellular domains of the arabidopsis receptor-like kinase ACR4, its homologs and the Wox5 transcription factor. Meyer MR, et al. PLoS One, 2015. PMID 25756623, Free PMC Article
    5. Mapping the signaling network of BIN2 kinase using TurboID-mediated biotin labeling and phosphoproteomics. Kim TW, et al. Plant Cell, 2023 Mar 15. PMID 36660928, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Atcrk1-1 mutant had serious growth defects under continuous illumination. Semi-dwarf phenotype of Atcrk1-1 was accompanied with chlorophyll depletion, disturbed photosynthesis, accumulation of singlet oxygen, and enhanced cell death in photosynthetic tissues.
      Title: Functional Analysis of the Arabidopsis thaliana CDPK-Related Kinase Family: AtCRK1 Regulates Responses to Continuous Light.
    2. Calmodulin-binding protein kinase 3 controls the binding activity of heat shock factors to heat shock elements, and is part of the heat-shock signal transduction pathway. [CBK3]
      Title: The calmodulin-binding protein kinase 3 is part of heat-shock signal transduction in Arabidopsis thaliana.
    3. An AtCRK1 [Arabidopsis thaliana CDPK (Ca2+-dependent protein kinase)-related protein kinase 1] has been characterized molecularly and biochemically. [CRK1]
      Title: Characterization of a calmodulin-regulated Ca2+-dependent-protein-kinase-related protein kinase, AtCRK1, from Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_129679.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables calcium/calmodulin-dependent protein kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables calmodulin binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in heat acclimation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein autophosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    CDPK-related kinase 1
    NP_181647.1
    • CDPK-related kinase 1 (CRK1); FUNCTIONS IN: calcium-dependent protein serine/threonine phosphatase activity, calmodulin-dependent protein kinase activity, kinase activity, calcium ion binding; INVOLVED IN: protein amino acid phosphorylation, N-terminal protein myristoylation; LOCATED IN: plasma membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Calcium-dependent protein kinase (InterPro:IPR020642), Calcium/calmodulin-dependent protein kinase-like (InterPro:IPR020636), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: Protein kinase superfamily protein (TAIR:AT3G56760.1); Has 116311 Blast hits to 114570 proteins in 3026 species: Archae - 154; Bacteria - 14640; Metazoa - 43033; Fungi - 12673; Plants - 24419; Viruses - 507; Other Eukaryotes - 20885 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      17150095..17153693
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_129679.2 → NP_181647.1  CDPK-related kinase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_181647.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O80673
      UniProtKB/TrEMBL
      A0A178VNU4, A0A5S9X5X9, A0A654F0T0
      Conserved Domains (1) summary
      cd05117
      Location:122 → 384
      STKc_CAMK; The catalytic domain of CAMK family Serine/Threonine Kinases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O80673.1

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