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    Disease resistance protein (TIR-NBS-LRR class) family [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842679, updated on 18-Sep-2024

    Summary

    Official Full Name
    Disease resistance protein (TIR-NBS-LRR class) family
    Primary source
    TAIR:AT1G63750
    Locus tag
    AT1G63750
    See related
    Araport:AT1G63750
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F24D7.6; F24D7_6
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    Try the new Transcript table

    Genomic context

    Location:
    chromosome: 1
    Exon count:
    4
    Sequence:
    Chromosome: 1; NC_003070.9 (23650840..23655453)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Disease resistance protein (TIR-NBS-LRR class) family Neighboring gene miscRNA Neighboring gene miscRNA Neighboring gene Peptidase M1 family protein Neighboring gene ncRNA

    General gene information

    NM_001084299.1
    NM_001084300.2
    NM_105052.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ADP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus ISM
    Inferred from Sequence Model
    more info
     
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
     

    General protein information

    Preferred Names
    Disease resistance protein (TIR-NBS-LRR class) family
    NP_001077768.1
    • Disease resistance protein (TIR-NBS-LRR class) family; FUNCTIONS IN: nucleoside-triphosphatase activity, nucleotide binding, ATP binding; INVOLVED IN: defense response, apoptosis; EXPRESSED IN: 7 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), NB-ARC (InterPro:IPR002182), Leucine-rich repeat (InterPro:IPR001611), Disease resistance protein (InterPro:IPR000767); BEST Arabidopsis thaliana protein match is: Disease resistance protein (TIR-NBS-LRR class) family (TAIR:AT5G58120.1); Has 21268 Blast hits to 16638 proteins in 741 species: Archae - 13; Bacteria - 2093; Metazoa - 2188; Fungi - 103; Plants - 16269; Viruses - 13; Other Eukaryotes - 589 (source: NCBI BLink).
    NP_001077769.1
    • Disease resistance protein (TIR-NBS-LRR class) family; FUNCTIONS IN: transmembrane receptor activity, nucleoside-triphosphatase activity, nucleotide binding, ATP binding; INVOLVED IN: signal transduction, apoptosis, defense response, innate immune response; LOCATED IN: intrinsic to membrane; EXPRESSED IN: 7 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), NB-ARC (InterPro:IPR002182), Leucine-rich repeat (InterPro:IPR001611), Toll-Interleukin receptor (InterPro:IPR000157), Disease resistance protein (InterPro:IPR000767); BEST Arabidopsis thaliana protein match is: Disease resistance protein (TIR-NBS-LRR class) family (TAIR:AT5G58120.1); Has 22087 Blast hits to 17235 proteins in 755 species: Archae - 13; Bacteria - 2137; Metazoa - 2175; Fungi - 113; Plants - 17053; Viruses - 13; Other Eukaryotes - 583 (source: NCBI BLink).
    NP_176562.2
    • Disease resistance protein (TIR-NBS-LRR class) family; FUNCTIONS IN: nucleoside-triphosphatase activity, nucleotide binding, ATP binding; INVOLVED IN: defense response, apoptosis; EXPRESSED IN: 7 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), NB-ARC (InterPro:IPR002182), Leucine-rich repeat (InterPro:IPR001611), Disease resistance protein (InterPro:IPR000767); BEST Arabidopsis thaliana protein match is: Disease resistance protein (TIR-NBS-LRR class) family (TAIR:AT5G58120.1); Has 21268 Blast hits to 16638 proteins in 741 species: Archae - 13; Bacteria - 2093; Metazoa - 2188; Fungi - 103; Plants - 16269; Viruses - 13; Other Eukaryotes - 589 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      23650840..23655453
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001084300.2NP_001077769.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001077769.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W1U0, Q9CAE0
      Conserved Domains (5) summary
      PLN03210
      Location:6948
      PLN03210; Resistant to P. syringae 6; Provisional
      cd00116
      Location:577830
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:559608
      LRR_RI; leucine-rich repeat [structural motif]
      pfam01582
      Location:18183
      TIR; TIR domain
      pfam13191
      Location:193240
      AAA_16; AAA ATPase domain
    2. NM_105052.5NP_176562.2  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_176562.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4I3Q8, Q0WVU9
      Conserved Domains (5) summary
      cd00116
      Location:410663
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:392441
      LRR_RI; leucine-rich repeat [structural motif]
      pfam00931
      Location:27279
      NB-ARC; NB-ARC domain
      pfam07725
      Location:441460
      LRR_3; Leucine Rich Repeat
      pfam13207
      Location:4870
      AAA_17; AAA domain
    3. NM_001084299.1NP_001077768.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001077768.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4I3Q8, Q0WVU9
      Conserved Domains (5) summary
      cd00116
      Location:410663
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:392441
      LRR_RI; leucine-rich repeat [structural motif]
      pfam00931
      Location:27279
      NB-ARC; NB-ARC domain
      pfam07725
      Location:441460
      LRR_3; Leucine Rich Repeat
      pfam13207
      Location:4870
      AAA_17; AAA domain