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    EIL3 ETHYLENE-INSENSITIVE3-like 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843708, updated on 18-Sep-2024

    Summary

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    Official Symbol
    EIL3
    Official Full Name
    ETHYLENE-INSENSITIVE3-like 3
    Primary source
    TAIR:AT1G73730
    Locus tag
    AT1G73730
    See related
    Araport:AT1G73730
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA SULFUR LIMITATION 1; AtEIL3; ATSLIM; ETHYLENE-INSENSITIVE3-like 3; F25P22.15; F25P22_15; SLIM1; SULFUR LIMITATION 1
    Summary
    Encodes a putative transcription factor involved in ethylene signalling. Isolated DNA binding domain has been shown to bind DNA in vitro.
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    Genomic context

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    See EIL3 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    3
    Sequence:
    Chromosome: 1; NC_003070.9 (27730031..27732683, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene transducin family protein / WD-40 repeat family protein Neighboring gene UDP-Glycosyltransferase superfamily protein Neighboring gene alpha/beta hydrolase family protein Neighboring gene RING/U-box superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The SLIM1 transcription factor is required for arsenic resistance in Arabidopsis thaliana. Jobe TO, et al. FEBS Lett, 2021 Jun. PMID 33960401, Free PMC Article
    2. Solution structure of the major DNA-binding domain of Arabidopsis thaliana ethylene-insensitive3-like3. Yamasaki K, et al. J Mol Biol, 2005 Apr 29. PMID 15811366
    3. The Transcription Factor EIL1 Participates in the Regulation of Sulfur-Deficiency Response. Dietzen C, et al. Plant Physiol, 2020 Dec. PMID 33060195, Free PMC Article
    4. Arabidopsis SLIM1 is a central transcriptional regulator of plant sulfur response and metabolism. Maruyama-Nakashita A, et al. Plant Cell, 2006 Nov. PMID 17114350, Free PMC Article
    5. EIN3 interferes with the sulfur deficiency signaling in Arabidopsis thaliana through direct interaction with the SLIM1 transcription factor. Wawrzyńska A, et al. Plant Sci, 2016 Dec. PMID 27968996

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The SLIM1 transcription factor is required for arsenic resistance in Arabidopsis thaliana.
      Title: The SLIM1 transcription factor is required for arsenic resistance in Arabidopsis thaliana.
    2. possible regulatory mechanism of ethylene in sulfur metabolism through direct EIN3-SLIM1 interaction
      Title: EIN3 interferes with the sulfur deficiency signaling in Arabidopsis thaliana through direct interaction with the SLIM1 transcription factor.
    3. SLIM1, both through the action of miR395 and independently, is responsible for the increased translocation of sulfate from roots to shoots during sulfate starvation, and also for the increased rate of sulfate reduction.
      Title: Interplay of SLIM1 and miR395 in the regulation of sulfate assimilation in Arabidopsis.
    4. DNA-binding domain NMR structure of EIL3
      Title: Solution structure of the major DNA-binding domain of Arabidopsis thaliana ethylene-insensitive3-like3.
    5. SLIM1 functioned as a central transcriptional regulator, which controlled both the activation of sulfate acquisition and degradation of glucosinolates under -S conditions.[SLIM1]
      Title: Arabidopsis SLIM1 is a central transcriptional regulator of plant sulfur response and metabolism.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001334601.1
    NM_106032.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to sulfate starvation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within cellular response to sulfate starvation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within ethylene-activated signaling pathway TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of DNA-templated transcription TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of sulfur metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in intracellular anatomical structure TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    ETHYLENE-INSENSITIVE3-like 3
    NP_177514.1
    • ETHYLENE-INSENSITIVE3-like 3 (EIL3); FUNCTIONS IN: DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: ethylene mediated signaling pathway, cellular response to sulfate starvation, regulation of sulfur metabolic process, regulation of transcription; LOCATED IN: nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ethylene insensitive 3 (InterPro:IPR006957); BEST Arabidopsis thaliana protein match is: Ethylene insensitive 3 family protein (TAIR:AT3G20770.1); Has 298 Blast hits to 298 proteins in 81 species: Archae - 0; Bacteria - 53; Metazoa - 2; Fungi - 1; Plants - 234; Viruses - 4; Other Eukaryotes - 4 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      27730031..27732683 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_106032.5 → NP_177514.1  ETHYLENE-INSENSITIVE3-like 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_177514.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O23116
      UniProtKB/TrEMBL
      A0A178VZZ3, A0A5S9WU37, A0A7G2E8P8
      Conserved Domains (1) summary
      PLN03109
      Location:1 → 567
      PLN03109; ETHYLENE-INSENSITIVE3-like3 protein; Provisional

    2. NM_001334601.1 → NP_001322105.1  ETHYLENE-INSENSITIVE3-like 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AT39, A0A7G2E8P8
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O23116.1

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