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    DNA glycosylase superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819984, updated on 18-Sep-2024

    Summary

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    Official Full Name
    DNA glycosylase superfamily protein
    Primary source
    TAIR:AT3G07930
    Locus tag
    AT3G07930
    See related
    Araport:AT3G07930
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    2
    Sequence:
    Chromosome: 3; NC_003074.8 (2526513..2528639)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene O-fucosyltransferase family protein Neighboring gene reactive oxygen species modulator-like protein Neighboring gene Translation initiation factor IF2/IF5 Neighboring gene Calcium-dependent ARF-type GTPase activating protein family Neighboring gene rhomboid protein-like protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Alternative splicing of an exitron determines the subnuclear localization of the Arabidopsis DNA glycosylase MBD4L under heat stress. Cecchini NM, et al. Plant J, 2022 Apr. PMID 35061303
    2. Expression and function of AtMBD4L, the single gene encoding the nuclear DNA glycosylase MBD4L in Arabidopsis. Nota F, et al. Plant Sci, 2015 Jun. PMID 25900572
    3. The Arabidopsis DNA glycosylase MBD4L repairs the nuclear genome in vivo. Torres JR, et al. Plant J, 2023 Sep. PMID 37278489
    4. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    NM_001337751.1
    NM_111672.3
    NM_202523.1
    NM_202524.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA N-glycosylase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in base-excision repair IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cell death IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within cellular response to heat IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to heat IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to oxidative stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    DNA glycosylase superfamily protein
    NP_566325.1
    • DNA glycosylase superfamily protein; Has 117 Blast hits to 117 proteins in 38 species: Archae - 0; Bacteria - 0; Metazoa - 67; Fungi - 0; Plants - 44; Viruses - 0; Other Eukaryotes - 6 (source: NCBI BLink).
    NP_974252.1
    • DNA glycosylase superfamily protein; Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_974253.1
    • DNA glycosylase superfamily protein; FUNCTIONS IN: catalytic activity; INVOLVED IN: DNA repair, base-excision repair; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA glycosylase (InterPro:IPR011257), HhH-GPD domain (InterPro:IPR003265); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      2526513..2528639
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111672.3 → NP_566325.1  DNA glycosylase superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566325.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VF15

    2. NM_001337751.1 → NP_001327391.1  DNA glycosylase superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0IGK1

    3. NM_202524.2 → NP_974253.1  DNA glycosylase superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974253.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4JFQ3, Q0IGK1, Q3EBA6, Q84WT3, Q8LB76, Q9SFC1
      UniProtKB/TrEMBL
      A0A178VGP7, A0A5S9XA47
      Conserved Domains (1) summary
      cl23768
      Location:319 → 389
      ENDO3c; endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases

    4. NM_202523.1 → NP_974252.1  DNA glycosylase superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974252.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VF15
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0IGK1.1

    Gene LinkOut

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