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    SAR1B secretion-associated RAS 1B [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842086, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SAR1B
    Official Full Name
    secretion-associated RAS 1B
    Primary source
    TAIR:AT1G56330
    Locus tag
    AT1G56330
    See related
    Araport:AT1G56330
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA SECRETION-ASSOCIATED RAS 1B; ATSAR1; ATSAR1B; ATSARA1B; F14G9.6; F14G9_6; SAR1; SARL; SECRETION-ASSOCIATED RAS 1; secretion-associated RAS 1B
    Summary
    Encodes a small GTP-binding protein implicated in ER to cis-Golgi transport of other proteins. A member of ARF-like GTPase family. A thaliana has 21 members, in two subfamilies, ARF and ARF-like (ARL) GTPases. The protein is found associated to the ER and free in the cytosol.
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    Genomic context

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    See SAR1B in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    3
    Sequence:
    Chromosome: 1; NC_003070.9 (21086501..21088554, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene CwfJ-like family protein Neighboring gene Chaperone DnaJ-domain superfamily protein Neighboring gene Polynucleotidyl transferase, ribonuclease H-like superfamily protein Neighboring gene uncharacterized protein Neighboring gene calreticulin 1a Neighboring gene Pseudouridine synthase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis Sar1b is critical for pollen tube growth. Liang X, et al. Plant Mol Biol, 2024 May 29. PMID 38809410
    2. Elements proximal to and within the transmembrane domain mediate the organelle-to-organelle movement of bZIP28 under ER stress conditions. Srivastava R, et al. Plant J, 2012 Jun. PMID 22335396
    3. A putative Arabidopsis nucleoporin, AtNUP160, is critical for RNA export and required for plant tolerance to cold stress. Dong CH, et al. Mol Cell Biol, 2006 Dec. PMID 17030626, Free PMC Article
    4. Characterization of AtSEC12 and AtSAR1. Proteins likely involved in endoplasmic reticulum and Golgi transport. Bar-Peled M, et al. Plant Physiol, 1997 May. PMID 9159953, Free PMC Article
    5. Analysis of the small GTPase gene superfamily of Arabidopsis. Vernoud V, et al. Plant Physiol, 2003 Mar. PMID 12644670, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Arabidopsis Sar1b is critical for pollen tube growth.
      Title: Arabidopsis Sar1b is critical for pollen tube growth.
    2. NUP160 is critical for nucleocytoplasmic transport of mRNAs, plays important role in plant growth and flowering time regulation, and is required for cold stress tolerance.
      Title: A putative Arabidopsis nucleoporin, AtNUP160, is critical for RNA export and required for plant tolerance to cold stress.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_104512.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables GTP binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within endoplasmic reticulum to Golgi vesicle-mediated transport TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane HDA PubMed 

    General protein information

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    Preferred Names
    secretion-associated RAS 1B
    NP_176029.1
    • secretion-associated RAS 1B (SAR1B); FUNCTIONS IN: GTP binding; INVOLVED IN: ER to Golgi vesicle-mediated transport; LOCATED IN: cytosol, peripheral to membrane of membrane fraction, endoplasmic reticulum, plasma membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Small GTP-binding protein (InterPro:IPR005225), Small GTPase SAR1-type (InterPro:IPR006687), ARF/SAR superfamily (InterPro:IPR006689); BEST Arabidopsis thaliana protein match is: secretion-associated RAS super family 2 (TAIR:AT4G02080.1); Has 6720 Blast hits to 6718 proteins in 371 species: Archae - 2; Bacteria - 32; Metazoa - 3237; Fungi - 1226; Plants - 1080; Viruses - 0; Other Eukaryotes - 1143 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      21086501..21088554 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_104512.3 → NP_176029.1  secretion-associated RAS 1B [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_176029.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q01474
      UniProtKB/TrEMBL
      A0A178WM97, A0A5S9TDR2, A0A5S9WQ64, A0A654E9N5
      Conserved Domains (1) summary
      smart00178
      Location:4 → 192
      SAR; Sar1p-like members of the Ras-family of small GTPases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q01474.1

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