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    PLP3a thioredoxin domain PLP3A-like protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824260, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PLP3a
    Official Full Name
    thioredoxin domain PLP3A-like protein
    Primary source
    TAIR:AT3G50960
    Locus tag
    AT3G50960
    See related
    Araport:AT3G50960
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    phosducin-like protein 3 homolog
    Summary
    Encodes a protein that functions in microtubule assembly. PLP3a can bind to several different tubulin family members in Y2H assays. Plants with reduced levels of both PLP3a and PLP3b (At5g66410) show defects in cytokinesis, cortical microtubule array formation, oriented cell growth, and maintenance of proper ploidy.
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    Genomic context

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    See PLP3a in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    9
    Sequence:
    Chromosome: 3; NC_003074.8 (18938697..18940428, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene ncRNA Neighboring gene HOPZ-ACTIVATED RESISTANCE 1 Neighboring gene dehydrin family protein Neighboring gene dehydrin xero 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Phosducin-Like Protein 3 is required for microtubule-dependent steps of cell division but not for meristem growth in Arabidopsis. Castellano MM, et al. Plant Cell, 2008 Apr. PMID 18390592, Free PMC Article
    2. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    3. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001339487.1
    NM_114956.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables beta-tubulin binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cortical microtubule organization IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    thioredoxin domain PLP3A-like protein
    NP_190665.2
    • phosducin-like protein 3 homolog (PLP3a); CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Thioredoxin domain (InterPro:IPR013766), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: phosducin-like protein 3 homolog (TAIR:AT5G66410.1); Has 968 Blast hits to 967 proteins in 239 species: Archae - 4; Bacteria - 68; Metazoa - 389; Fungi - 149; Plants - 170; Viruses - 0; Other Eukaryotes - 188 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      18938697..18940428 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_114956.3 → NP_190665.2  thioredoxin domain PLP3A-like protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_190665.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q6NPL9, Q9SVK3
      UniProtKB/TrEMBL
      A0A178VB62, A0A5S9XKH9
      Conserved Domains (1) summary
      cd02989
      Location:81 → 190
      Phd_like_TxnDC9; Phosducin (Phd)-like family, Thioredoxin (TRX) domain containing protein 9 (TxnDC9) subfamily; composed of predominantly uncharacterized eukaryotic proteins, containing a TRX-like domain without the redox active CXXC motif. The gene name for the human ...

    2. NM_001339487.1 → NP_001325881.1  thioredoxin domain PLP3A-like protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q6NPL9, Q9SVK3
      UniProtKB/TrEMBL
      A0A178VB62, A0A5S9XKH9
      Conserved Domains (1) summary
      cd02989
      Location:81 → 190
      Phd_like_TxnDC9; Phosducin (Phd)-like family, Thioredoxin (TRX) domain containing protein 9 (TxnDC9) subfamily; composed of predominantly uncharacterized eukaryotic proteins, containing a TRX-like domain without the redox active CXXC motif. The gene name for the human ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6NPL9.1

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