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    DHDPS1 dihydrodipicolinate synthase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 825259, updated on 18-Sep-2024

    Summary

    Official Symbol
    DHDPS1
    Official Full Name
    dihydrodipicolinate synthase 1
    Primary source
    TAIR:AT3G60880
    Locus tag
    AT3G60880
    See related
    Araport:AT3G60880
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    DHDPS; DIHYDRODIPICOLINATE SYNTHASE; dihydrodipicolinate synthase 1
    Summary
    Encodes a dihydropicolinate synthase involved in lysine biosynthesis. The enzyme is allosterically inhibited by lysine. It is predicted to localize to the cholorplast.
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    Genomic context

    See DHDPS1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    3
    Sequence:
    Chromosome: 3; NC_003074.8 (22494739..22496697)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene SEC7-like guanine nucleotide exchange family protein Neighboring gene AT-hook motif nuclear-localized protein 18 Neighboring gene binding protein Neighboring gene FASCICLIN-like arabinogalactan-protein 10

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    NM_115952.2
    NM_180399.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 4-hydroxy-tetrahydrodipicolinate synthase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in lysine biosynthetic process via diaminopimelate IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
     

    General protein information

    Preferred Names
    dihydrodipicolinate synthase 1
    NP_191647.1
    • dihydrodipicolinate synthase 1 (DHDPS1); FUNCTIONS IN: dihydrodipicolinate synthase activity; INVOLVED IN: lysine biosynthetic process via diaminopimelate, metabolic process, diaminopimelate biosynthetic process; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aldolase-type TIM barrel (InterPro:IPR013785), Dihydrodipicolinate synthase subfamily (InterPro:IPR005263), Dihydrodipicolinate synthetase (InterPro:IPR002220), Dihydrodipicolinate synthetase, active site (InterPro:IPR020625), Dihydrodipicolinate synthetase, conserved site (InterPro:IPR020624); BEST Arabidopsis thaliana protein match is: dihydrodipicolinate synthase (TAIR:AT2G45440.1); Has 13092 Blast hits to 13092 proteins in 2641 species: Archae - 342; Bacteria - 9390; Metazoa - 97; Fungi - 273; Plants - 96; Viruses - 0; Other Eukaryotes - 2894 (source: NCBI BLink).
    NP_850730.1
    • dihydrodipicolinate synthase 1 (DHDPS1); FUNCTIONS IN: dihydrodipicolinate synthase activity; INVOLVED IN: lysine biosynthetic process via diaminopimelate, diaminopimelate biosynthetic process, metabolic process; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aldolase-type TIM barrel (InterPro:IPR013785), Dihydrodipicolinate synthase subfamily (InterPro:IPR005263), Dihydrodipicolinate synthetase (InterPro:IPR002220), Dihydrodipicolinate synthetase, active site (InterPro:IPR020625), Dihydrodipicolinate synthetase, conserved site (InterPro:IPR020624); BEST Arabidopsis thaliana protein match is: dihydrodipicolinate synthase (TAIR:AT2G45440.1); Has 13228 Blast hits to 13228 proteins in 2671 species: Archae - 342; Bacteria - 9527; Metazoa - 96; Fungi - 273; Plants - 96; Viruses - 0; Other Eukaryotes - 2894 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      22494739..22496697
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_180399.3NP_850730.1  dihydrodipicolinate synthase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850730.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O49355, Q8VZQ1, Q9LZX6, Q9SW58
      UniProtKB/TrEMBL
      A0A178V8R0, A0A5S9XMV8, A0A654FJL5
      Conserved Domains (1) summary
      PLN02417
      Location:64343
      PLN02417; dihydrodipicolinate synthase
    2. NM_115952.2NP_191647.1  dihydrodipicolinate synthase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_191647.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V8R0, A0A5S9XMV8
      Conserved Domains (1) summary
      PLN02417
      Location:63342
      PLN02417; dihydrodipicolinate synthase