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    AZG2 Xanthine/uracil permease family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835095, updated on 18-Sep-2024

    Summary

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    Official Symbol
    AZG2
    Official Full Name
    Xanthine/uracil permease family protein
    Primary source
    TAIR:AT5G50300
    Locus tag
    AT5G50300
    See related
    Araport:AT5G50300
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA AZA-GUANINE RESISTANT2; ATAZG2; AZA-GUANINE RESISTANT2; K6A12.16; K6A12_16
    Summary
    Encodes a homolog of the adenine-guanine-hypoxanthine transporter AzgA of Aspergillus nidulans. Function as a plant adenine-guanine transporter. Two closely related genes exist in Arabidopsis: AT3G10960 (Azg1) and AT5G50300 (Azg2).
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    Genomic context

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    See AZG2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    1
    Sequence:
    Chromosome: 5; NC_003076.8 (20466068..20468217, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene F-box/RNI-like/FBD-like domains-containing protein Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene wall-associated receptor kinase galacturonan-binding protein Neighboring gene ncRNA Neighboring gene Galactose oxidase/kelch repeat superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis AZG2 transports cytokinins in vivo and regulates lateral root emergence. Tessi TM, et al. New Phytol, 2021 Jan. PMID 33070379
    2. AtAzg1 and AtAzg2 comprise a novel family of purine transporters in Arabidopsis. Mansfield TA, et al. FEBS Lett, 2009 Jan 22. PMID 19121308
    3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Arabidopsis AZG2 transports cytokinins in vivo and regulates lateral root emergence.
      Title: Arabidopsis AZG2 transports cytokinins in vivo and regulates lateral root emergence.
    2. AtAzg2 acts as adenine-guanine transporter.
      Title: AtAzg1 and AtAzg2 comprise a novel family of purine transporters in Arabidopsis.
    Submit: New GeneRIF Correction

    General gene information

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    NM_124409.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables adenine nucleotide transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables guanine nucleotide transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables nucleobase transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables purine nucleobase transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in adenine nucleotide transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in adenine transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in guanine nucleotide transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in guanine transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within purine nucleobase transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Xanthine/uracil permease family protein
    NP_199841.2
    • AZA-GUANINE RESISTANT2 (AZG2); FUNCTIONS IN: transporter activity, purine transmembrane transporter activity; INVOLVED IN: transport, purine transport; LOCATED IN: membrane; EXPRESSED IN: root; CONTAINS InterPro DOMAIN/s: Xanthine/uracil/vitamin C permease (InterPro:IPR006043); BEST Arabidopsis thaliana protein match is: AZA-guanine resistant1 (TAIR:AT3G10960.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      20466068..20468217 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001344886.1 → NP_001332453.1  Xanthine/uracil permease family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UDZ6, A0A1P8BH09, A0A5S9YCR1

    2. NM_124409.4 → NP_199841.2  Xanthine/uracil permease family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_199841.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q84MA8, Q9FGR5
      UniProtKB/TrEMBL
      A0A178UDZ6, A0A5S9YCR1, A0A654GAM9
      Conserved Domains (1) summary
      COG2252
      Location:24 → 494
      AzgA; Xanthine/uracil/vitamin C permease, AzgA family [Nucleotide transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q84MA8.1

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