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    AKINBETA1 5'-AMP-activated protein kinase beta-2 subunit protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 832243, updated on 18-Sep-2024

    Summary

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    Official Symbol
    AKINBETA1
    Official Full Name
    5'-AMP-activated protein kinase beta-2 subunit protein
    Primary source
    TAIR:AT5G21170
    Locus tag
    AT5G21170
    See related
    Araport:AT5G21170
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    KINbeta1; T10F18.200; T10F18_200
    Summary
    Encodes AKINbeta1, a subunit of the SnRK1 kinase (Sucrose non-fermenting-1-related protein kinase). Involved in regulation of nitrogen and sugar metabolism.
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    Genomic context

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    See AKINBETA1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    5
    Sequence:
    Chromosome: 5; NC_003076.8 (7205477..7208613)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene LA RNA-binding protein Neighboring gene miscRNA Neighboring gene protein kinase family protein Neighboring gene calmodulin 6

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. AKINβ1, a subunit of SnRK1, regulates organic acid metabolism and acts as a global modulator of genes involved in carbon, lipid, and nitrogen metabolism. Wang Y, et al. J Exp Bot, 2020 Jan 23. PMID 31624846
    2. AKINbeta1 is involved in the regulation of nitrogen metabolism and sugar signaling in Arabidopsis. Li XF, et al. J Integr Plant Biol, 2009 May. PMID 19397750
    3. A novel role for Arabidopsis CBL1 in affecting plant responses to glucose and gibberellin during germination and seedling development. Li ZY, et al. PLoS One, 2013. PMID 23437128, Free PMC Article
    4. A role for the carbohydrate-binding module (CBM) in regulatory SnRK1 subunits: the effect of maltose on SnRK1 activity. Ruiz-Gayosso A, et al. Plant J, 2018 Oct. PMID 30003611
    5. The hybrid four-CBS-domain KINβγ subunit functions as the canonical γ subunit of the plant energy sensor SnRK1. Ramon M, et al. Plant J, 2013 Jul. PMID 23551663, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. AKINbeta1, a subunit of SnRK1, regulates organic acid metabolism and acts as a global modulator of genes involved in carbon, lipid, and nitrogen metabolism.
      Title: AKINβ1, a subunit of SnRK1, regulates organic acid metabolism and acts as a global modulator of genes involved in carbon, lipid, and nitrogen metabolism.
    2. AKINbeta1 negatively regulates the activity of nitrate ruductase and is positively involved in sugar repression in early seedling development. [AKINbeta1]
      Title: AKINbeta1 is involved in the regulation of nitrogen metabolism and sugar signaling in Arabidopsis.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001036841.2
    NM_001343699.1
    NM_122124.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables maltose binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein kinase regulator activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to nitrogen levels IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    part_of nucleotide-activated protein kinase complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    5'-AMP-activated protein kinase beta-2 subunit protein
    NP_001031918.2
    • AKINBETA1; FUNCTIONS IN: AMP-activated protein kinase activity; INVOLVED IN: N-terminal protein myristoylation, cellular response to nitrogen levels; LOCATED IN: chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: 5-AMP-activated protein kinase, beta subunit, interaction domain (InterPro:IPR006828); BEST Arabidopsis thaliana protein match is: 5'-AMP-activated protein kinase beta-2 subunit protein (TAIR:AT4G16360.3); Has 674 Blast hits to 666 proteins in 192 species: Archae - 0; Bacteria - 0; Metazoa - 246; Fungi - 149; Plants - 202; Viruses - 0; Other Eukaryotes - 77 (source: NCBI BLink).
    NP_197615.1
    • AKINBETA1; FUNCTIONS IN: AMP-activated protein kinase activity; INVOLVED IN: N-terminal protein myristoylation, cellular response to nitrogen levels; LOCATED IN: chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: 5-AMP-activated protein kinase, beta subunit, interaction domain (InterPro:IPR006828); BEST Arabidopsis thaliana protein match is: 5'-AMP-activated protein kinase beta-2 subunit protein (TAIR:AT4G16360.3); Has 697 Blast hits to 689 proteins in 198 species: Archae - 0; Bacteria - 3; Metazoa - 248; Fungi - 167; Plants - 204; Viruses - 0; Other Eukaryotes - 75 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      7205477..7208613
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_122124.4 → NP_197615.1  5'-AMP-activated protein kinase beta-2 subunit protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_197615.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q84VQ1, Q9SCY6
      UniProtKB/TrEMBL
      A0A5S9Y617, A0A654G3E6, Q29Q48
      Conserved Domains (2) summary
      pfam04739
      Location:213 → 279
      AMPKBI; 5'-AMP-activated protein kinase beta subunit, interaction domain
      pfam16561
      Location:101 → 184
      AMPK1_CBM; Glycogen recognition site of AMP-activated protein kinase

    2. NM_001036841.2 → NP_001031918.2  5'-AMP-activated protein kinase beta-2 subunit protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031918.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9Y617, A0A654G3E6, Q2V357
      Conserved Domains (2) summary
      smart01010
      Location:233 → 318
      AMPKBI; 5'-AMP-activated protein kinase beta subunit, interation domain
      pfam16561
      Location:138 → 221
      AMPK1_CBM; Glycogen recognition site of AMP-activated protein kinase

    3. NM_001343699.1 → NP_001330544.1  5'-AMP-activated protein kinase beta-2 subunit protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BB45
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q84VQ1.1

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