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    Cd52 CD52 antigen [ Mus musculus (house mouse) ]

    Gene ID: 23833, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cd52provided by MGI
    Official Full Name
    CD52 antigenprovided by MGI
    Primary source
    MGI:MGI:1346088
    See related
    Ensembl:ENSMUSG00000000682 AllianceGenome:MGI:1346088
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    B7; MB7; CLS1; B7-Ag; CAMPATH-1
    Summary
    Acts upstream of or within response to bacterium. Located in sperm midpiece. Is expressed in embryo mesenchyme and thymus primordium. Orthologous to human CD52 (CD52 molecule). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in genital fat pad adult (RPKM 628.5), spleen adult (RPKM 137.4) and 4 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Cd52 in Genome Data Viewer
    Location:
    4 D2.3; 4 66.5 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (133820849..133822384, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (134093538..134095073, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 683 Neighboring gene crystallin beta-gamma domain containing 2 Neighboring gene STARR-positive B cell enhancer ABC_E1658 Neighboring gene STARR-positive B cell enhancer ABC_E9600 Neighboring gene STARR-positive B cell enhancer ABC_E842 Neighboring gene STARR-positive B cell enhancer ABC_E4678 Neighboring gene STARR-positive B cell enhancer ABC_E10264 Neighboring gene UBX domain protein 11 Neighboring gene STARR-seq mESC enhancer starr_11667 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:133677585-133677803 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:133680177-133680360 Neighboring gene SH3 domain binding glutamic acid-rich protein-like 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (8) 
    • Targeted (3)  1 citation

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in side of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in sperm midpiece IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in sperm midpiece IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    CAMPATH-1 antigen
    Names
    lymphocyte differentiation antigen B7

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_013706.2NP_038734.1  CAMPATH-1 antigen precursor

      See identical proteins and their annotated locations for NP_038734.1

      Status: VALIDATED

      Source sequence(s)
      AK155728, BC027495
      Consensus CDS
      CCDS38909.1
      UniProtKB/Swiss-Prot
      Q64389
      UniProtKB/TrEMBL
      Q3U1T8
      Related
      ENSMUSP00000000696.7, ENSMUST00000000696.7
      Conserved Domains (1) summary
      pfam15116
      Location:3774
      CD52; CAMPATH-1 antigen

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      133820849..133822384 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)