U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Agpat3 1-acylglycerol-3-phosphate O-acyltransferase 3 [ Mus musculus (house mouse) ]

    Gene ID: 28169, updated on 3-Dec-2024

    Summary

    Official Symbol
    Agpat3provided by MGI
    Official Full Name
    1-acylglycerol-3-phosphate O-acyltransferase 3provided by MGI
    Primary source
    MGI:MGI:1336186
    See related
    Ensembl:ENSMUSG00000001211 AllianceGenome:MGI:1336186
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    lpaat3; D10Jhu12e
    Summary
    Enables lysophosphatidic acid acyltransferase activity. Predicted to be involved in CDP-diacylglycerol biosynthetic process. Located in endoplasmic reticulum. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Orthologous to human AGPAT3 (1-acylglycerol-3-phosphate O-acyltransferase 3). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in testis adult (RPKM 65.3), adrenal adult (RPKM 53.5) and 26 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Agpat3 in Genome Data Viewer
    Location:
    10 C1; 10 39.72 cM
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (78105008..78188335, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (78269174..78352497, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_27217 Neighboring gene trafficking protein particle complex 10 Neighboring gene STARR-seq mESC enhancer starr_27219 Neighboring gene predicted gene, 30122 Neighboring gene STARR-positive B cell enhancer ABC_E3894 Neighboring gene STARR-seq mESC enhancer starr_27222 Neighboring gene microRNA 7659 Neighboring gene predicted gene, 40709 Neighboring gene LSM7 homolog, U6 small nuclear RNA associated pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (2)  1 citation

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables 1-acylglycerol-3-phosphate O-acyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables 1-acylglycerol-3-phosphate O-acyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables 1-acylglycerol-3-phosphate O-acyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables lysophosphatidic acid acyltransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in CDP-diacylglycerol biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in endomembrane system IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nuclear envelope ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear envelope ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    1-acyl-sn-glycerol-3-phosphate acyltransferase gamma
    Names
    1-AGP acyltransferase 3
    1-AGPAT 3
    LPAAT-gamma
    lysophosphatidic acid acyltransferase 3
    lysophosphatidic acid acyltransferase gamma
    NP_001391799.1
    NP_001391800.1
    NP_001391801.1
    NP_001391802.1
    NP_001391803.1
    NP_001391804.1
    NP_001391805.1
    NP_001391806.1
    NP_001391807.1
    NP_001391808.1
    NP_001391809.1
    NP_001391810.1
    NP_001391811.1
    NP_443747.2
    XP_006513781.1
    XP_036011691.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001404870.1NP_001391799.1  1-acyl-sn-glycerol-3-phosphate acyltransferase gamma isoform a

      Status: VALIDATED

      Source sequence(s)
      AC160405
      UniProtKB/Swiss-Prot
      C4B4E7, Q7TT39, Q8BST2, Q9D517
      UniProtKB/TrEMBL
      Q3TXT9
    2. NM_001404871.1NP_001391800.1  1-acyl-sn-glycerol-3-phosphate acyltransferase gamma isoform a

      Status: VALIDATED

      Source sequence(s)
      AC160405
      UniProtKB/Swiss-Prot
      C4B4E7, Q7TT39, Q8BST2, Q9D517
      UniProtKB/TrEMBL
      Q3TXT9
    3. NM_001404872.1NP_001391801.1  1-acyl-sn-glycerol-3-phosphate acyltransferase gamma isoform a

      Status: VALIDATED

      Source sequence(s)
      AC160405
      UniProtKB/Swiss-Prot
      C4B4E7, Q7TT39, Q8BST2, Q9D517
      UniProtKB/TrEMBL
      Q3TXT9
      Related
      ENSMUSP00000101026.2, ENSMUST00000105387.8
    4. NM_001404873.1NP_001391802.1  1-acyl-sn-glycerol-3-phosphate acyltransferase gamma isoform a

      Status: VALIDATED

      Source sequence(s)
      AC160405
      UniProtKB/Swiss-Prot
      C4B4E7, Q7TT39, Q8BST2, Q9D517
      UniProtKB/TrEMBL
      Q3TXT9
    5. NM_001404874.1NP_001391803.1  1-acyl-sn-glycerol-3-phosphate acyltransferase gamma isoform a

      Status: VALIDATED

      Source sequence(s)
      AC160405
      UniProtKB/Swiss-Prot
      C4B4E7, Q7TT39, Q8BST2, Q9D517
      UniProtKB/TrEMBL
      Q3TXT9
      Related
      ENSMUSP00000101028.2, ENSMUST00000105389.8
    6. NM_001404875.1NP_001391804.1  1-acyl-sn-glycerol-3-phosphate acyltransferase gamma isoform a

      Status: VALIDATED

      Source sequence(s)
      AC160405, AC160411
      UniProtKB/Swiss-Prot
      C4B4E7, Q7TT39, Q8BST2, Q9D517
      UniProtKB/TrEMBL
      Q3TXT9
      Related
      ENSMUSP00000001240.6, ENSMUST00000001240.12
    7. NM_001404876.1NP_001391805.1  1-acyl-sn-glycerol-3-phosphate acyltransferase gamma isoform a

      Status: VALIDATED

      Source sequence(s)
      AC160405, AC160411
      UniProtKB/Swiss-Prot
      C4B4E7, Q7TT39, Q8BST2, Q9D517
      UniProtKB/TrEMBL
      Q3TXT9
    8. NM_001404877.1NP_001391806.1  1-acyl-sn-glycerol-3-phosphate acyltransferase gamma isoform a

      Status: VALIDATED

      Source sequence(s)
      AC160405
      UniProtKB/Swiss-Prot
      C4B4E7, Q7TT39, Q8BST2, Q9D517
      UniProtKB/TrEMBL
      Q3TXT9
    9. NM_001404878.1NP_001391807.1  1-acyl-sn-glycerol-3-phosphate acyltransferase gamma isoform b

      Status: VALIDATED

      Source sequence(s)
      AC160405, AC160411
    10. NM_001404879.1NP_001391808.1  1-acyl-sn-glycerol-3-phosphate acyltransferase gamma isoform b

      Status: VALIDATED

      Source sequence(s)
      AC160405
    11. NM_001404880.1NP_001391809.1  1-acyl-sn-glycerol-3-phosphate acyltransferase gamma isoform b

      Status: VALIDATED

      Source sequence(s)
      AC160405
    12. NM_001404881.1NP_001391810.1  1-acyl-sn-glycerol-3-phosphate acyltransferase gamma isoform c

      Status: VALIDATED

      Source sequence(s)
      AC160405
    13. NM_001404882.1NP_001391811.1  1-acyl-sn-glycerol-3-phosphate acyltransferase gamma isoform d

      Status: VALIDATED

      Source sequence(s)
      AC160405
    14. NM_053014.4NP_443747.2  1-acyl-sn-glycerol-3-phosphate acyltransferase gamma isoform a

      See identical proteins and their annotated locations for NP_443747.2

      Status: VALIDATED

      Source sequence(s)
      AC160405, AC160411
      Consensus CDS
      CCDS23963.1
      UniProtKB/Swiss-Prot
      C4B4E7, Q7TT39, Q8BST2, Q9D517
      UniProtKB/TrEMBL
      Q3TXT9
      Conserved Domains (1) summary
      PLN02380
      Location:12325
      PLN02380; 1-acyl-sn-glycerol-3-phosphate acyltransferase

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      78105008..78188335 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006513718.1XP_006513781.1  1-acyl-sn-glycerol-3-phosphate acyltransferase gamma isoform X1

      See identical proteins and their annotated locations for XP_006513781.1

      UniProtKB/Swiss-Prot
      C4B4E7, Q7TT39, Q8BST2, Q9D517
      UniProtKB/TrEMBL
      Q3TXT9
      Related
      ENSMUSP00000101029.2, ENSMUST00000105390.8
      Conserved Domains (1) summary
      PLN02380
      Location:12325
      PLN02380; 1-acyl-sn-glycerol-3-phosphate acyltransferase
    2. XM_036155798.1XP_036011691.1  1-acyl-sn-glycerol-3-phosphate acyltransferase gamma isoform X1

      UniProtKB/Swiss-Prot
      C4B4E7, Q7TT39, Q8BST2, Q9D517
      UniProtKB/TrEMBL
      Q3TXT9
      Conserved Domains (1) summary
      PLN02380
      Location:12325
      PLN02380; 1-acyl-sn-glycerol-3-phosphate acyltransferase