U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Cox6b1 cytochrome c oxidase, subunit 6B1 [ Mus musculus (house mouse) ]

    Gene ID: 110323, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cox6b1provided by MGI
    Official Full Name
    cytochrome c oxidase, subunit 6B1provided by MGI
    Primary source
    MGI:MGI:107460
    See related
    Ensembl:ENSMUSG00000036751 AllianceGenome:MGI:107460
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Cox6b; COX VIb-1; 2010000G05Rik
    Summary
    Predicted to be involved in oxidative phosphorylation. Located in mitochondrial inner membrane. Is expressed in several structures, including alimentary system; heart; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 7. Orthologous to human COX6B1 (cytochrome c oxidase subunit 6B1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in heart adult (RPKM 546.5), kidney adult (RPKM 430.4) and 27 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Cox6b1 in Genome Data Viewer
    Location:
    7 B1; 7 18.84 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (30316396..30325539, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (30616971..30626114, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer mm9_chr7:31374455-31374756 Neighboring gene STARR-positive B cell enhancer ABC_E11347 Neighboring gene STARR-positive B cell enhancer ABC_E11348 Neighboring gene zinc finger and BTB domain containing 32 Neighboring gene STARR-seq mESC enhancer starr_18526 Neighboring gene uroplakin 1A Neighboring gene STARR-positive B cell enhancer ABC_E2232 Neighboring gene STARR-seq mESC enhancer starr_18529 Neighboring gene ets variant 2 Neighboring gene RNA binding motif protein 42 Neighboring gene STARR-positive B cell enhancer ABC_E545

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    cytochrome c oxidase subunit 6B1
    Names
    cytochrome c oxidase, subunit VIb polypeptide 1
    NP_079904.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025628.3NP_079904.1  cytochrome c oxidase subunit 6B1

      See identical proteins and their annotated locations for NP_079904.1

      Status: VALIDATED

      Source sequence(s)
      AK007996, AW047421
      Consensus CDS
      CCDS39887.1
      UniProtKB/Swiss-Prot
      P56391, Q545A3
      Related
      ENSMUSP00000075150.5, ENSMUST00000075738.6
      Conserved Domains (1) summary
      cd00926
      Location:885
      Cyt_c_Oxidase_VIb; Cytochrome c oxidase subunit VIb. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of ...

    RNA

    1. NR_157092.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AW047421, BY379769

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      30316396..30325539 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)