Ift70a1 intraflagellar transport 70A1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Ift70a1provided by MGI
Official Full Name: intraflagellar transport 70A1provided by MGI
Primary source: MGI:MGI:1926052
See related: Ensembl:ENSMUSG00000075271 AllianceGenome:MGI:1926052
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Ttc30a1; 4930506L13Rik
Summary: Enables intraciliary transport particle B binding activity. Predicted to be involved in intraciliary transport. Predicted to act upstream of or within intraciliary anterograde transport. Located in centrosome and cilium. Part of intraciliary transport particle B. Orthologous to human IFT70A (intraflagellar transport 70A). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

Location:: 2 C3; 2 44.8 cM

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	2	NC_000068.8 (75809450..75812311, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	2	NC_000068.7 (75979106..75981967, complement)

Chromosome 2 - NC_000068.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Ttc30a1 is most abundantly expressed in tissues rich in highly ciliated cells, such as olfactory sensory neurons, and is predicted to be important to cilia.
Title: Tissue expression patterns identify mouse cilia genes.

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables intraciliary transport particle B binding	IBA Inferred from Biological aspect of Ancestor more info
enables intraciliary transport particle B binding	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within intraciliary anterograde transport	IC Inferred by Curator more info	PubMed
involved_in intraciliary transport	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in axonemal microtubule	IBA Inferred from Biological aspect of Ancestor more info
located_in centrosome	IDA Inferred from Direct Assay more info	PubMed
located_in cilium	IDA Inferred from Direct Assay more info	PubMed
part_of intraciliary transport particle B	IBA Inferred from Biological aspect of Ancestor more info
part_of intraciliary transport particle B	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: intraflagellar transport protein 70A1

Names: TPR repeat protein 30A1; novel tetratrico peptide repeat (TPR) containing protein; tetratricopeptide repeat domain 30A; tetratricopeptide repeat domain 30A1; tetratricopeptide repeat protein 30A1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_030188.3 → NP_084464.3 intraflagellar transport protein 70A1

See identical proteins and their annotated locations for NP_084464.3

Status: VALIDATED

Source sequence(s)

AK045096, BU610816

Consensus CDS

CCDS16154.1

UniProtKB/Swiss-Prot

Q8C0X1, Q99J38

Related

ENSMUSP00000097574.4, ENSMUST00000099994.5

Conserved Domains (2) summary

TIGR02917
Location:15 → 216

PEP_TPR_lipo; putative PEP-CTERM system TPR-repeat lipoprotein

sd00006
Location:44 → 74

TPR; TPR repeat [structural motif]