TO1 thioredoxin O1 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: TO1
Official Full Name: thioredoxin O1
Primary source: TAIR:AT2G35010
Locus tag: AT2G35010
See related: Araport:AT2G35010
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ATO1; F19I3.24; F19I3_24; thioredoxin O1
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Genomic context

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See TO1 in Genome Data Viewer

Location:: chromosome: 2

Exon count:: 6

Sequence:: Chromosome: 2; NC_003071.7 (14754234..14756323)

Chromosome 2 - NC_003071.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Thioredoxins o1 and h2 jointly adjust mitochondrial dihydrolipoamide dehydrogenase-dependent pathways towards changing environments.
Title: Thioredoxins o1 and h2 jointly adjust mitochondrial dihydrolipoamide dehydrogenase-dependent pathways towards changing environments.
Redox-Regulation of Photorespiration through Mitochondrial Thioredoxin o1.
Title: Redox-Regulation of Photorespiration through Mitochondrial Thioredoxin o1.
redox regulation via TRXo1 is necessary to allow the rapid induction of mitochondrial steps of the photorespiratory cycle and, in turn, to facilitate light-induction of photosynthesis.
Title: Redox-regulation of mitochondrial metabolism through thioredoxin o1 facilitates light induction of photosynthesis.
Results indicate a role for the AtTrxo1 gene in seed germination that is more evident in 100 mM NaCl, where Trxo1 could act as a possible sensor of saline stress and an inducer of H2O2 accumulation, independently of other ROS parameters (PrxIIF and AtSrx gene expression, protein oxidation, or lipid peroxidation). [Trxo1]
Title: Mitochondrial AtTrxo1 is transcriptionally regulated by AtbZIP9 and AtAZF2 and affects seed germination under saline conditions.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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NM_001084537.1

Supported by ESTs:

NM_129053.6

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor	IDA Inferred from Direct Assay more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within regulation of photorespiration	IGI Inferred from Genetic Interaction more info	PubMed

Component	Evidence Code	Pubs
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in cytosol	HDA more info	PubMed
located_in endoplasmic reticulum	HDA more info	PubMed
located_in mitochondrial matrix	IDA Inferred from Direct Assay more info	PubMed
located_in mitochondrion	HDA more info	PubMed

General protein information

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Preferred Names: thioredoxin O1

NP_001078006.1

thioredoxin O1 (TO1); INVOLVED IN: cell redox homeostasis; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Thioredoxin-like subdomain (InterPro:IPR006662), Thioredoxin, core (InterPro:IPR015467), Thioredoxin-like (InterPro:IPR017936), Thioredoxin domain (InterPro:IPR013766), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: thioredoxin O2 (TAIR:AT1G31020.1); Has 13800 Blast hits to 13766 proteins in 2821 species: Archae - 178; Bacteria - 7899; Metazoa - 1073; Fungi - 652; Plants - 1267; Viruses - 5; Other Eukaryotes - 2726 (source: NCBI BLink).

NP_181046.1

thioredoxin O1 (TO1); INVOLVED IN: cell redox homeostasis; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Thioredoxin-like subdomain (InterPro:IPR006662), Thioredoxin, core (InterPro:IPR015467), Thioredoxin-like (InterPro:IPR017936), Thioredoxin domain (InterPro:IPR013766), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: thioredoxin O2 (TAIR:AT1G31020.1); Has 13800 Blast hits to 13766 proteins in 2821 species: Archae - 178; Bacteria - 7899; Metazoa - 1073; Fungi - 652; Plants - 1267; Viruses - 5; Other Eukaryotes - 2726 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003071.7 Reference assembly

Range

14754234..14756323

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_129053.6 → NP_181046.1 thioredoxin O1 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_181046.1

Status: REVIEWED

UniProtKB/Swiss-Prot

O64764, Q8GW51

UniProtKB/TrEMBL

A0A178VSZ4, A0A5S9X4A1

Conserved Domains (1) summary

cd02947
Location:93 → 190

TRX_family; TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox ...
NM_001084537.1 → NP_001078006.1 thioredoxin O1 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_001078006.1

Status: REVIEWED

UniProtKB/Swiss-Prot

O64764, Q8GW51

UniProtKB/TrEMBL

A0A178VSZ4, A0A5S9X4A1

Conserved Domains (1) summary

cd02947
Location:93 → 190

TRX_family; TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox ...