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    SPPL3 SIGNAL PEPTIDE PEPTIDASE-LIKE 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818909, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SPPL3
    Official Full Name
    SIGNAL PEPTIDE PEPTIDASE-LIKE 3
    Primary source
    TAIR:AT2G43070
    Locus tag
    AT2G43070
    See related
    Araport:AT2G43070
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA SIGNAL PEPTIDE PEPTIDASE-LIKE 3; ATSPPL3; SIGNAL PEPTIDE PEPTIDASE-LIKE 3
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    Genomic context

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    See SPPL3 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    14
    Sequence:
    Chromosome: 2; NC_003071.7 (17910523..17915009, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Plant invertase/pectin methylesterase inhibitor superfamily Neighboring gene ILI1 binding bHLH 1 Neighboring gene P4H isoform 1 Neighboring gene Aconitase/3-isopropylmalate dehydratase protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Signal peptide peptidase and its homologs in Arabidopsis thaliana--plant tissue-specific expression and distinct subcellular localization. Tamura T, et al. FEBS J, 2008 Jan. PMID 18067581
    2. A proteomics dissection of Arabidopsis thaliana vacuoles isolated from cell culture. Jaquinod M, et al. Mol Cell Proteomics, 2007 Mar. PMID 17151019, Free PMC Article
    3. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385
    4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001337011.1
    NM_001337012.1
    NM_001337013.1
    NM_180052.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables aspartic endopeptidase activity, intramembrane cleaving IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endosome TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in plant-type vacuole HDA PubMed 
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    SIGNAL PEPTIDE PEPTIDASE-LIKE 3
    NP_001318409.1
    • SIGNAL PEPTIDE PEPTIDASE-LIKE 3 (SPPL3); FUNCTIONS IN: peptidase activity, aspartic-type endopeptidase activity; INVOLVED IN: proteolysis; LOCATED IN: plasma membrane; EXPRESSED IN: 8 plant structures; CONTAINS InterPro DOMAIN/s: Protease-associated PA (InterPro:IPR003137), Peptidase A22, presenilin signal peptide (InterPro:IPR006639), Peptidase A22B, signal peptide peptidase (InterPro:IPR007369); BEST Arabidopsis thaliana protein match is: SIGNAL PEPTIDE PEPTIDASE-LIKE 5 (TAIR:AT1G05820.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      17910523..17915009 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001337011.1 → NP_001318409.1  SIGNAL PEPTIDE PEPTIDASE-LIKE 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q4V3B8, Q9ZW87
      UniProtKB/TrEMBL
      A0A178VZ31, A0A5S9X6I8, A0A7G2EHS3
      Conserved Domains (2) summary
      cd02132
      Location:47 → 185
      PA_GO-like; Protease-associated domain containing proteins like Arabidopsis thaliana growth-on protein GRO10. This group contains various PA domain-containing proteins similar to the functionally uncharacterized Arabidopsis GRO10. The PA domain may be a ...
      pfam04258
      Location:244 → 524
      Peptidase_A22B; Signal peptide peptidase

    2. NM_001337012.1 → NP_001325361.1  SIGNAL PEPTIDE PEPTIDASE-LIKE 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B2Y2, A0A654F1E7, A0A7G2EK15
      Conserved Domains (2) summary
      cd02132
      Location:47 → 185
      PA_GO-like; Protease-associated domain containing proteins like Arabidopsis thaliana growth-on protein GRO10. This group contains various PA domain-containing proteins similar to the functionally uncharacterized Arabidopsis GRO10. The PA domain may be a ...
      pfam04258
      Location:250 → 530
      Peptidase_A22B; Signal peptide peptidase

    3. NM_180052.4 → NP_850383.3  SIGNAL PEPTIDE PEPTIDASE-LIKE 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B2Y1, A0A7G2EHS3

    4. NM_001337013.1 → NP_001325362.1  SIGNAL PEPTIDE PEPTIDASE-LIKE 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B2Y7, A0A7G2EK15
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q4V3B8.1

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