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    SRP2 serpin 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 815941, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SRP2
    Official Full Name
    serpin 2
    Primary source
    TAIR:AT2G14540
    Locus tag
    AT2G14540
    See related
    Araport:AT2G14540
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATSRP2; serpin 2; T13P21.8; T13P21_8
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    Genomic context

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    See SRP2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    2
    Sequence:
    Chromosome: 2; NC_003071.7 (6197663..6199406, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene miscRNA Neighboring gene miscRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Serpin genes AtSRP2 and AtSRP3 are required for normal growth sensitivity to a DNA alkylating agent in Arabidopsis. Ahn JW, et al. BMC Plant Biol, 2009 May 11. PMID 19426562, Free PMC Article
    2. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Expression of serpins AtSRP2 and AtSRP3 is required for normal responses of plants following exposure to alkylating genotoxins.
      Title: Serpin genes AtSRP2 and AtSRP3 are required for normal growth sensitivity to a DNA alkylating agent in Arabidopsis.
    Submit: New GeneRIF Correction

    General gene information

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    NM_127017.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA damage response IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within DNA repair IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serpin 2
    NP_179060.1
    • serpin 2 (SRP2); FUNCTIONS IN: serine-type endopeptidase inhibitor activity; INVOLVED IN: DNA repair, response to DNA damage stimulus; LOCATED IN: nucleus; EXPRESSED IN: fruit; CONTAINS InterPro DOMAIN/s: Protease inhibitor I4, serpin, plant (InterPro:IPR015554), Protease inhibitor I4, serpin (InterPro:IPR000215); BEST Arabidopsis thaliana protein match is: Serine protease inhibitor (SERPIN) family protein (TAIR:AT1G62170.1); Has 6246 Blast hits to 6203 proteins in 468 species: Archae - 66; Bacteria - 371; Metazoa - 4782; Fungi - 10; Plants - 340; Viruses - 461; Other Eukaryotes - 216 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      6197663..6199406 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127017.2 → NP_179060.1  serpin 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_179060.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9ZQR6
      UniProtKB/TrEMBL
      A0A178W286, A0A5S9WY36
      Conserved Domains (1) summary
      cl00137
      Location:36 → 397
      SERPIN; SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which regulate ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZQR6.1

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