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    LIP1 lipoic acid synthase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816619, updated on 18-Sep-2024

    Summary

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    Official Symbol
    LIP1
    Official Full Name
    lipoic acid synthase 1
    Primary source
    TAIR:AT2G20860
    Locus tag
    AT2G20860
    See related
    Araport:AT2G20860
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F5H14.17; F5H14_17; lipoic acid synthase 1
    Summary
    LIP1,Lipoic acid synthase
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    Genomic context

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    See LIP1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    5
    Sequence:
    Chromosome: 2; NC_003071.7 (8979554..8981923)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Secretory carrier membrane protein (SCAMP) family protein Neighboring gene STRUBBELIG-receptor family 1 Neighboring gene cell wall protein precursor Neighboring gene uncharacterized protein Neighboring gene epidermal patterning factor 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Biosynthesis of lipoic acid in Arabidopsis: cloning and characterization of the cDNA for lipoic acid synthase. Yasuno R, et al. Plant Physiol, 1998 Nov. PMID 9808738, Free PMC Article
    2. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    NM_001335714.1
    NM_001335715.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables lipoate synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables lipoate synthase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within glycine catabolic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within lipoate biosynthetic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within lipoate biosynthetic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitochondrial matrix IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    lipoic acid synthase 1
    NP_001318257.1
    • LIPOIC ACID SYNTHASE 1 (LIP1); FUNCTIONS IN: lipoic acid synthase activity; INVOLVED IN: lipoic acid biosynthetic process, glycine catabolic process; LOCATED IN: mitochondrion, mitochondrial matrix; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Aldolase-type TIM barrel (InterPro:IPR013785), Lipoate synthase (InterPro:IPR003698), Elongator protein 3/MiaB/NifB (InterPro:IPR006638), Radical SAM (InterPro:IPR007197); BEST Arabidopsis thaliana protein match is: lipoic acid synthase family protein (TAIR:AT5G08415.1); Has 5683 Blast hits to 5683 proteins in 1186 species: Archae - 36; Bacteria - 2370; Metazoa - 113; Fungi - 91; Plants - 53; Viruses - 0; Other Eukaryotes - 3020 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      8979554..8981923
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127655.4 → NP_179682.1  lipoic acid synthase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_179682.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9ZWT1
      UniProtKB/TrEMBL
      A0A178VME8, A0A5S9WZR5, A0A654EW98
      Conserved Domains (1) summary
      PLN02428
      Location:23 → 372
      PLN02428; lipoic acid synthase

    2. NM_001335714.1 → NP_001318257.1  lipoic acid synthase 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9ZWT1
      UniProtKB/TrEMBL
      A0A178VME8, A0A5S9WZR5, A0A654EW98
      Conserved Domains (1) summary
      PLN02428
      Location:23 → 372
      PLN02428; lipoic acid synthase

    3. NM_001335715.1 → NP_001323612.1  lipoic acid synthase 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9ZWT1
      UniProtKB/TrEMBL
      A0A178VME8, A0A5S9WZR5, A0A654EW98
      Conserved Domains (1) summary
      PLN02428
      Location:23 → 372
      PLN02428; lipoic acid synthase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZWT1.1

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