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    LUP1 lupeol synthase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 844237, updated on 18-Sep-2024

    Summary

    Official Symbol
    LUP1
    Official Full Name
    lupeol synthase 1
    Primary source
    TAIR:AT1G78970
    Locus tag
    AT1G78970
    See related
    Araport:AT1G78970
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA LUPEOL SYNTHASE 1; ATLUP1; lupeol synthase 1
    Summary
    Lupeol synthase. Converts oxidosqualene to multiple triterpene alcohols and a triterpene diols. This conversion proceeds through the formation of a 17beta-dammarenyl cation.
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    Genomic context

    See LUP1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    18
    Sequence:
    Chromosome: 1; NC_003070.9 (29703055..29708175)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene camelliol C synthase 1 Neighboring gene lupeol synthase 2 Neighboring gene STRUBBELIG-receptor family 5 Neighboring gene HXXXD-type acyl-transferase family protein Neighboring gene uncharacterized protein

    Pathways from PubChem

    Interactions

    General gene information

    NM_001334865.1
    NM_106546.3
    NM_179572.2

    Gene Ontology Provided by TAIR

    Component Evidence Code Pubs
    located_in lipid droplet  
    located_in nucleus  

    General protein information

    Preferred Names
    lupeol synthase 1
    NP_178018.1
    • lupeol synthase 1 (LUP1); CONTAINS InterPro DOMAIN/s: Terpene synthase, conserved site (InterPro:IPR002365), Terpenoid cylases/protein prenyltransferase alpha-alpha toroid (InterPro:IPR008930), Squalene cyclase (InterPro:IPR018333), Prenyltransferase/squalene oxidase (InterPro:IPR001330); BEST Arabidopsis thaliana protein match is: lupeol synthase 2 (TAIR:AT1G78960.1); Has 2106 Blast hits to 1984 proteins in 578 species: Archae - 2; Bacteria - 957; Metazoa - 82; Fungi - 241; Plants - 614; Viruses - 0; Other Eukaryotes - 210 (source: NCBI BLink).
    NP_849903.1
    • lupeol synthase 1 (LUP1); CONTAINS InterPro DOMAIN/s: Terpene synthase, conserved site (InterPro:IPR002365), Terpenoid cylases/protein prenyltransferase alpha-alpha toroid (InterPro:IPR008930), Squalene cyclase (InterPro:IPR018333), Prenyltransferase/squalene oxidase (InterPro:IPR001330); BEST Arabidopsis thaliana protein match is: lupeol synthase 2 (TAIR:AT1G78960.1); Has 2106 Blast hits to 1984 proteins in 578 species: Archae - 2; Bacteria - 957; Metazoa - 82; Fungi - 241; Plants - 614; Viruses - 0; Other Eukaryotes - 210 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      29703055..29708175
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_106546.3 → NP_178018.1  lupeol synthase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_178018.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O49985, O64551, P92977, Q9C5M3
      UniProtKB/TrEMBL
      A0A178WLB6, A0A5S9WVL5, A0A654EQ84
      Conserved Domains (1) summary
      PLN02993
      Location:1 → 757
      PLN02993; lupeol synthase
    2. NM_001334865.1 → NP_001321029.1  lupeol synthase 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O49985, O64551, P92977, Q9C5M3
      UniProtKB/TrEMBL
      A0A178WLB6, A0A5S9WVL5, A0A654EQ84
      Conserved Domains (1) summary
      PLN02993
      Location:1 → 757
      PLN02993; lupeol synthase
    3. NM_179572.2 → NP_849903.1  lupeol synthase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849903.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O49985, O64551, P92977, Q9C5M3
      UniProtKB/TrEMBL
      A0A178WLB6, A0A5S9WVL5, A0A654EQ84
      Conserved Domains (1) summary
      PLN02993
      Location:1 → 757
      PLN02993; lupeol synthase
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