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    MEF21 mitochondrial editing factor 21 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816576, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MEF21
    Official Full Name
    mitochondrial editing factor 21
    Primary source
    TAIR:AT2G20540
    Locus tag
    AT2G20540
    See related
    Araport:AT2G20540
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    mitochondrial editing factor 21; mitochondrial editing factor 21; T13C7.13; T13C7_13
    Summary
    Encodes a pentatricopeptide repeat protein (PPR) protein involved in mitochondrial mRNA editing.
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    Genomic context

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    See MEF21 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    2
    Sequence:
    Chromosome: 2; NC_003071.7 (8844079..8846095)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene FASCICLIN-like arabinogalactan 6 Neighboring gene prohibitin 6 Neighboring gene HSP40/DnaJ peptide-binding protein Neighboring gene miscRNA Neighboring gene DNAJ heat shock family protein Neighboring gene taximin

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Reverse genetic screening identifies five E-class PPR proteins involved in RNA editing in mitochondria of Arabidopsis thaliana. Takenaka M, et al. J Biol Chem, 2010 Aug 27. PMID 20566637, Free PMC Article
    2. Multiple organellar RNA editing factor (MORF) family proteins are required for RNA editing in mitochondria and plastids of plants. Takenaka M, et al. Proc Natl Acad Sci U S A, 2012 Mar 27. PMID 22411807, Free PMC Article
    3. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_127614.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA modification IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within mitochondrial mRNA modification IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    mitochondrial editing factor 21
    NP_179644.1
    • mitochondrial editing factor 21 (MEF21); CONTAINS InterPro DOMAIN/s: Pentatricopeptide repeat (InterPro:IPR002885); BEST Arabidopsis thaliana protein match is: Pentatricopeptide repeat (PPR) superfamily protein (TAIR:AT5G56310.1); Has 36443 Blast hits to 13667 proteins in 251 species: Archae - 0; Bacteria - 21; Metazoa - 39; Fungi - 110; Plants - 35693; Viruses - 0; Other Eukaryotes - 580 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      8844079..8846095
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001335693.1 → NP_001324532.1  mitochondrial editing factor 21 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VUA6, A0A1P8B0F7

    2. NM_127614.2 → NP_179644.1  mitochondrial editing factor 21 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_179644.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SIL5
      UniProtKB/TrEMBL
      A0A178VUA6, A0A5S9WZY1
      Conserved Domains (2) summary
      PLN03077
      Location:26 → 513
      PLN03077; Protein ECB2; Provisional
      sd00004
      Location:309 → 336
      PPR; PPR repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SIL5.1

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