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    RSZ21 RS-containing zinc finger protein 21 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838997, updated on 8-Dec-2024

    Summary

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    Official Symbol
    RSZ21
    Official Full Name
    RS-containing zinc finger protein 21
    Primary source
    TAIR:AT1G23860
    Locus tag
    AT1G23860
    See related
    Araport:AT1G23860
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    At-RSZ21; RS-containing zinc finger protein 21; RSZP21; SRZ-21; SRZ21; T23E23.2; T23E23_2
    Summary
    Encodes a 9G8-like serine-arginine rich (SR) protein that interacts in vivo with U1-70K, a U1 small nuclear ribonucleoprotein 70-kDa protein that is involved in nuclear precursor mRNA processing. Barta et al (2010) have proposed a nomenclature for Serine/Arginine-Rich Protein Splicing Factors (SR proteins): Plant Cell. 2010, 22:2926.
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    Genomic context

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    See RSZ21 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    6
    Sequence:
    Chromosome: 1; NC_003070.9 (8427257..8429498, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene trehalose-phosphatase/synthase 9 Neighboring gene NHL domain-containing protein Neighboring gene NHL domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A novel family of plant splicing factors with a Zn knuckle motif: examination of RNA binding and splicing activities. Lopato S, et al. Plant Mol Biol, 1999 Mar. PMID 10350090
    2. The plant U1 small nuclear ribonucleoprotein particle 70K protein interacts with two novel serine/arginine-rich proteins. Golovkin M, et al. Plant Cell, 1998 Oct. PMID 9761791, Free PMC Article
    3. An SC35-like protein and a novel serine/arginine-rich protein interact with Arabidopsis U1-70K protein. Golovkin M, et al. J Biol Chem, 1999 Dec 17. PMID 10593939
    4. Phosphothreonine 218 is required for the function of SR45.1 in regulating flower petal development in Arabidopsis. Zhang XN, et al. Plant Signal Behav, 2014. PMID 25763493, Free PMC Article
    5. Transportin-SR is required for proper splicing of resistance genes and plant immunity. Xu S, et al. PLoS Genet, 2011 Jun. PMID 21738492, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001123870.4
    NM_001198145.1
    NM_202172.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within mRNA splicing, via spliceosome TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nuclear speck IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    RS-containing zinc finger protein 21
    NP_001117342.1
    • SRZ-21; FUNCTIONS IN: protein binding; INVOLVED IN: nuclear mRNA splicing, via spliceosome; LOCATED IN: nuclear speck, nucleus; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677), Zinc finger, CCHC-type (InterPro:IPR001878); BEST Arabidopsis thaliana protein match is: serine/arginine-rich 22 (TAIR:AT4G31580.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_001185074.1
    • RS-containing zinc finger protein 21 (RSZP21); CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677), Zinc finger, CCHC-type (InterPro:IPR001878); BEST Arabidopsis thaliana protein match is: serine/arginine-rich 22 (TAIR:AT4G31580.2).
    NP_564208.1
    • RS-containing zinc finger protein 21 (RSZP21); FUNCTIONS IN: protein binding; INVOLVED IN: nuclear mRNA splicing, via spliceosome; LOCATED IN: nuclear speck, nucleus; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677), Zinc finger, CCHC-type (InterPro:IPR001878); BEST Arabidopsis thaliana protein match is: serine/arginine-rich 22 (TAIR:AT4G31580.2); Has 6291 Blast hits to 5531 proteins in 385 species: Archae - 0; Bacteria - 201; Metazoa - 3437; Fungi - 488; Plants - 1566; Viruses - 48; Other Eukaryotes - 551 (source: NCBI BLink).
    NP_973901.1
    • SRZ-21; FUNCTIONS IN: protein binding; INVOLVED IN: nuclear mRNA splicing, via spliceosome; LOCATED IN: nuclear speck, nucleus; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677), Zinc finger, CCHC-type (InterPro:IPR001878); BEST Arabidopsis thaliana protein match is: serine/arginine-rich 22 (TAIR:AT4G31580.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      8427257..8429498 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_102234.4 → NP_564208.1  RS-containing zinc finger protein 21 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564208.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B3H6W9, F4I7M9, O23645, O81127, Q9LRA8
      UniProtKB/TrEMBL
      A0A178WC08, A0A5S9VS92, A0A654ECJ2
      Conserved Domains (2) summary
      pfam00098
      Location:90 → 104
      zf-CCHC; Zinc knuckle
      cd12373
      Location:3 → 70
      RRM_SRSF3_like; RNA recognition motif (RRM) found in serine/arginine-rich splicing factor 3 (SRSF3) and similar proteins

    2. NM_001123870.4 → NP_001117342.1  RS-containing zinc finger protein 21 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001117342.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654ECJ2
      Conserved Domains (3) summary
      COG0724
      Location:2 → 59
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12373
      Location:3 → 70
      RRM_SRSF3_like; RNA recognition motif in serine/arginine-rich splicing factor 3 (SRSF3) and similar proteins
      pfam00098
      Location:90 → 104
      zf-CCHC; Zinc knuckle

    3. NM_001198145.1 → NP_001185074.1  RS-containing zinc finger protein 21 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001185074.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654ECJ2
      Conserved Domains (3) summary
      COG0724
      Location:2 → 59
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12373
      Location:3 → 70
      RRM_SRSF3_like; RNA recognition motif in serine/arginine-rich splicing factor 3 (SRSF3) and similar proteins
      pfam00098
      Location:90 → 104
      zf-CCHC; Zinc knuckle

    4. NM_202172.1 → NP_973901.1  RS-containing zinc finger protein 21 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_973901.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B3H6W9, F4I7M9, O23645, O81127, Q9LRA8
      UniProtKB/TrEMBL
      A0A178WC08, A0A5S9VS92, A0A654ECJ2
      Conserved Domains (2) summary
      pfam00098
      Location:90 → 104
      zf-CCHC; Zinc knuckle
      cd12373
      Location:3 → 70
      RRM_SRSF3_like; RNA recognition motif (RRM) found in serine/arginine-rich splicing factor 3 (SRSF3) and similar proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O81127.1

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