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    Major facilitator superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838861, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Major facilitator superfamily protein
    Primary source
    TAIR:AT1G22550
    Locus tag
    AT1G22550
    See related
    Araport:AT1G22550
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F12K8.11; F12K8_11
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    4
    Sequence:
    Chromosome: 1; NC_003070.9 (7966500..7968692, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene PATELLIN 2 Neighboring gene Major facilitator superfamily protein Neighboring gene pseudo Neighboring gene Major facilitator superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Tonoplast-localized nitrate uptake transporters involved in vacuolar nitrate efflux and reallocation in Arabidopsis. He YN, et al. Sci Rep, 2017 Jul 25. PMID 28743909, Free PMC Article
    2. Uncovering Arabidopsis membrane protein interactome enriched in transporters using mating-based split ubiquitin assays and classification models. Chen J, et al. Front Plant Sci, 2012. PMID 22737156, Free PMC Article
    3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. At1g22550 (NPF5.16) is involved in the nitrate from vacuoles into cytosol, thus serving as important player to modulate nitrate allocation between roots and shoots.
      Title: Tonoplast-localized nitrate uptake transporters involved in vacuolar nitrate efflux and reallocation in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_102104.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables dipeptide transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables low-affinity nitrate transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables tripeptide transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within nitrate transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plant-type vacuole membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Major facilitator superfamily protein
    NP_173671.1
    • Major facilitator superfamily protein; FUNCTIONS IN: transporter activity; INVOLVED IN: oligopeptide transport; LOCATED IN: membrane; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: PTR2 family proton/oligopeptide symporter, conserved site (InterPro:IPR018456), Oligopeptide transporter (InterPro:IPR000109), Major facilitator superfamily, general substrate transporter (InterPro:IPR016196); BEST Arabidopsis thaliana protein match is: Major facilitator superfamily protein (TAIR:AT1G22570.1); Has 7743 Blast hits to 7641 proteins in 1463 species: Archae - 0; Bacteria - 4037; Metazoa - 494; Fungi - 461; Plants - 2187; Viruses - 0; Other Eukaryotes - 564 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      7966500..7968692 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_102104.4 → NP_173671.1  Major facilitator superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_173671.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q84VX2, Q9SK96
      UniProtKB/TrEMBL
      A0A178WGZ5, A0A5S9VJD9
      Conserved Domains (1) summary
      cl21472
      Location:141 → 522
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SK96.1

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