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    SR45a RNA-binding (RRM/RBD/RNP motifs) family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837246, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SR45a
    Official Full Name
    RNA-binding (RRM/RBD/RNP motifs) family protein
    Primary source
    TAIR:AT1G07350
    Locus tag
    AT1G07350
    See related
    Araport:AT1G07350
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F22G5.31; F22G5_31; serine/arginine rich-like protein 45a
    Summary
    Encodes a serine/arginine rich-like protein, SR45a. Involved in the regulation of stress-responsive alternative splicing.
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    Genomic context

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    See SR45a in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    8
    Sequence:
    Chromosome: 1; NC_003070.9 (2257384..2260187, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene dentin sialophosphoprotein Neighboring gene sugar transporter 2 Neighboring gene CCCH-type zinc fingerfamily protein with RNA-binding domain-containing protein Neighboring gene proliferating cellular nuclear antigen 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dual roles of the serine/arginine-rich splicing factor SR45a in promoting and interacting with nuclear cap-binding complex to modulate the salt-stress response in Arabidopsis. Li Y, et al. New Phytol, 2021 Apr. PMID 33421141
    2. Identification of alternative splicing events regulated by an Arabidopsis serine/arginine-like protein, atSR45a, in response to high-light stress using a tiling array. Yoshimura K, et al. Plant Cell Physiol, 2011 Oct. PMID 21862516
    3. Plant-specific SR-related protein atSR45a interacts with spliceosomal proteins in plant nucleus. Tanabe N, et al. Plant Mol Biol, 2009 Jun. PMID 19238562
    4. Phosphoproteomics reveals extensive in vivo phosphorylation of Arabidopsis proteins involved in RNA metabolism. de la Fuente van Bentem S, et al. Nucleic Acids Res, 2006. PMID 16807317, Free PMC Article
    5. Extensive signal integration by the phytohormone protein network. Altmann M, et al. Nature, 2020 Jul. PMID 32612234

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Dual roles of the serine/arginine-rich splicing factor SR45a in promoting and interacting with nuclear cap-binding complex to modulate the salt-stress response in Arabidopsis.
      Title: Dual roles of the serine/arginine-rich splicing factor SR45a in promoting and interacting with nuclear cap-binding complex to modulate the salt-stress response in Arabidopsis.
    2. atSR45a is involved in the regulation of alternative splicing, which may serve as part of the response to high-light stress. [atSR45a]
      Title: Identification of alternative splicing events regulated by an Arabidopsis serine/arginine-like protein, atSR45a, in response to high-light stress using a tiling array.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001331692.1
    NM_001331693.1
    NM_001331694.1
    NM_001331695.1
    NM_100609.4
    NM_179274.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within RNA splicing NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of RNA splicing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to high light intensity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    RNA-binding (RRM/RBD/RNP motifs) family protein
    NP_563787.2
    • RNA-binding (RRM/RBD/RNP motifs) family protein; FUNCTIONS IN: RNA binding, nucleotide binding, nucleic acid binding; INVOLVED IN: RNA splicing; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: RNA-binding (RRM/RBD/RNP motifs) family protein (TAIR:AT4G35785.1); Has 998067 Blast hits to 992400 proteins in 35925 species: Archae - 21556; Bacteria - 596698; Metazoa - 207042; Fungi - 24534; Plants - 55970; Viruses - 68919; Other Eukaryotes - 23348 (source: NCBI BLink).
    NP_849605.1
    • RNA-binding (RRM/RBD/RNP motifs) family protein; FUNCTIONS IN: RNA binding, nucleotide binding, nucleic acid binding; INVOLVED IN: RNA splicing; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: RNA-binding (RRM/RBD/RNP motifs) family protein (TAIR:AT4G35785.3); Has 999351 Blast hits to 998918 proteins in 36088 species: Archae - 21775; Bacteria - 603314; Metazoa - 202027; Fungi - 24253; Plants - 55487; Viruses - 69473; Other Eukaryotes - 23022 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      2257384..2260187 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_179274.2 → NP_849605.1  RNA-binding (RRM/RBD/RNP motifs) family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849605.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q84TH4
      Conserved Domains (2) summary
      COG0724
      Location:32 → 120
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cl17169
      Location:44 → 120
      RRM_SF; RNA recognition motif (RRM) superfamily

    2. NM_001331692.1 → NP_001323001.1  RNA-binding (RRM/RBD/RNP motifs) family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q84TH4

    3. NM_100609.4 → NP_563787.2  RNA-binding (RRM/RBD/RNP motifs) family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_563787.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q84TH4, Q940S1, Q949Y9, Q9LNV4
      UniProtKB/TrEMBL
      A0A7G2DRB7
      Conserved Domains (2) summary
      COG0724
      Location:62 → 151
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cl17169
      Location:74 → 151
      RRM_SF; RNA recognition motif (RRM) superfamily

    4. NM_001331694.1 → NP_001323002.1  RNA-binding (RRM/RBD/RNP motifs) family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q84TH4

    5. NM_001331693.1 → NP_001323003.1  RNA-binding (RRM/RBD/RNP motifs) family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AVR1

    6. NM_001331695.1 → NP_001323004.1  RNA-binding (RRM/RBD/RNP motifs) family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AVT0
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q84TH4.1

    Gene LinkOut

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