U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    QSOX1 quiescin-sulfhydryl oxidase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838067, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    QSOX1
    Official Full Name
    quiescin-sulfhydryl oxidase 1
    Primary source
    TAIR:AT1G15020
    Locus tag
    AT1G15020
    See related
    Araport:AT1G15020
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATQSOX1; QSO2; quiescin-sulfhydryl oxidase 1; T15D22.7; T15D22_7
    Summary
    Encodes a protein disulfide isomerase-like (PDIL) protein, a member of a multigene family within the thioredoxin (TRX) superfamily. This protein also belongs to the quiescin-sulfhydryl oxidase (QSOX) family, which possess an Erv1-like domain at the COOH terminus in addition to a TRX domain.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See QSOX1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    13
    Sequence:
    Chromosome: 1; NC_003070.9 (5172232..5176479, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene mediator of RNA polymerase II transcription subunit Neighboring gene F-box family protein Neighboring gene hypothetical protein (DUF789) Neighboring gene ncRNA Neighboring gene Class I glutamine amidotransferase-like superfamily protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. S-nitrosylation switches the Arabidopsis redox sensor protein, QSOX1, from an oxidoreductase to a molecular chaperone under heat stress. Chae HB, et al. Plant Physiol Biochem, 2024 Jan. PMID 38048703
    2. An Arabidopsis quiescin-sulfhydryl oxidase regulates cation homeostasis at the root symplast-xylem interface. Alejandro S, et al. EMBO J, 2007 Jul 11. PMID 17568770, Free PMC Article
    3. Separating Golgi Proteins from Cis to Trans Reveals Underlying Properties of Cisternal Localization. Parsons HT, et al. Plant Cell, 2019 Sep. PMID 31266899, Free PMC Article
    4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. S-nitrosylation switches the Arabidopsis redox sensor protein, QSOX1, from an oxidoreductase to a molecular chaperone under heat stress.
      Title: S-nitrosylation switches the Arabidopsis redox sensor protein, QSOX1, from an oxidoreductase to a molecular chaperone under heat stress.
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help
    NM_101371.5
    NM_179333.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables flavin-dependent sulfhydryl oxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables thiol oxidase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of potassium ion transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to cation stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi cis cisterna HDA PubMed 
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  
    colocalizes_with plant-type cell wall IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    quiescin-sulfhydryl oxidase 1
    NP_172955.1
    • quiescin-sulfhydryl oxidase 1 (QSOX1); FUNCTIONS IN: thiol oxidase activity, zinc ion binding; INVOLVED IN: response to cation stress; LOCATED IN: endomembrane system; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Zinc finger, RING-type (InterPro:IPR001841), Erv1/Alr (InterPro:IPR006863), Thioredoxin domain (InterPro:IPR013766), Thioredoxin, conserved site (InterPro:IPR017937), ERV/ALR sulphydryl oxidase (InterPro:IPR017905), Thioredoxin-like (InterPro:IPR017936), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: quiescin-sulfhydryl oxidase 2 (TAIR:AT2G01270.1); Has 2372 Blast hits to 1975 proteins in 299 species: Archae - 18; Bacteria - 46; Metazoa - 1235; Fungi - 321; Plants - 448; Viruses - 0; Other Eukaryotes - 304 (source: NCBI BLink).
    NP_849664.1
    • quiescin-sulfhydryl oxidase 1 (QSOX1); FUNCTIONS IN: thiol oxidase activity, zinc ion binding; INVOLVED IN: response to cation stress; LOCATED IN: endomembrane system; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Zinc finger, RING-type (InterPro:IPR001841), Erv1/Alr (InterPro:IPR006863), Thioredoxin domain (InterPro:IPR013766), Thioredoxin, conserved site (InterPro:IPR017937), ERV/ALR sulphydryl oxidase (InterPro:IPR017905), Thioredoxin-like (InterPro:IPR017936), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: quiescin-sulfhydryl oxidase 2 (TAIR:AT2G01270.1); Has 2363 Blast hits to 1967 proteins in 298 species: Archae - 18; Bacteria - 44; Metazoa - 1234; Fungi - 321; Plants - 442; Viruses - 0; Other Eukaryotes - 304 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      5172232..5176479 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001332143.1 → NP_001321934.1  quiescin-sulfhydryl oxidase 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2DT99

    2. NM_179333.2 → NP_849664.1  quiescin-sulfhydryl oxidase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849664.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2DT99
      Conserved Domains (2) summary
      cd02992
      Location:41 → 161
      PDI_a_QSOX; PDIa family, Quiescin-sulfhydryl oxidase (QSOX) subfamily; QSOX is a eukaryotic protein containing an N-terminal redox active TRX domain, similar to that of PDI, and a small C-terminal flavin adenine dinucleotide (FAD)-binding domain homologous to the ...
      pfam04777
      Location:305 → 394
      Evr1_Alr; Erv1 / Alr family

    3. NM_101371.5 → NP_172955.1  quiescin-sulfhydryl oxidase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_172955.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q3EDC3, Q8W4J3, Q9M9Q3
      UniProtKB/TrEMBL
      A0A178W7Y5
      Conserved Domains (2) summary
      cd02992
      Location:41 → 161
      PDI_a_QSOX; PDIa family, Quiescin-sulfhydryl oxidase (QSOX) subfamily; QSOX is a eukaryotic protein containing an N-terminal redox active TRX domain, similar to that of PDI, and a small C-terminal flavin adenine dinucleotide (FAD)-binding domain homologous to the ...
      pfam04777
      Location:305 → 394
      Evr1_Alr; Erv1 / Alr family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8W4J3.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.