RPK1 receptor-like protein kinase 1 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: RPK1
Official Full Name: receptor-like protein kinase 1
Primary source: TAIR:AT1G69270
Locus tag: AT1G69270
See related: Araport:AT1G69270
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: AtRPK1; F4N2.27; F4N2_27; receptor-like protein kinase 1; RECEPTOR-LIKE PROTEIN KINASE 1
Summary: RPK1 is a leucine-rich receptor-like kinase located in the plasma membrane which is upregulated by abscisic acid, dehydration, high salt, low temperature, but not by other plant hormones. RPK1 knock-out and antisense plants show an ABA-insensitive phenotype. RPK1 plays a role in ABA-controlled cell proliferation and is a regulator of the ABA signal transduction pathway. Overexpression of the LRR domain has a dominant negative effect on RPK1. Mutations in RPK1 uncouple cotyledon anlagen and primordia by modulating epidermal cell shape and polarity.
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Genomic context

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See RPK1 in Genome Data Viewer

Location:: chromosome: 1

Exon count:: 1

Sequence:: Chromosome: 1; NC_003070.9 (26040689..26042741, complement)

Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

BAK1-induced RPK1 phosphorylation is essential for RPK1-mediated cell death in Arabidopsis.
Title: BAK1-induced RPK1 phosphorylation is essential for RPK1-mediated cell death in Arabidopsis.
Receptor-like protein kinases RPK1 and BAK1 sequentially form complexes with the cytoplasmic kinase OST1 to regulate ABA-induced stomatal closure.
Title: Receptor-like protein kinases RPK1 and BAK1 sequentially form complexes with the cytoplasmic kinase OST1 to regulate ABA-induced stomatal closure.
According to rpk1's auxin-related PIN1 defect, seedlings displayed defects in vascular tissue. Shoot apical meristem (SAM)-less seedlings variably expressed essential SAM specific genes along the hypocotyl-cotyledon structure into the cotyledon lamina.
Title: Ectopic shoot meristem generation in monocotyledonous rpk1 mutants is linked to SAM loss and altered seedling morphology.
Mutations in the Arabidopsis RPK1 gene uncouple cotyledon anlagen and primordia by modulating epidermal cell shape and polarity.
Title: Mutations in the Arabidopsis RPK1 gene uncouple cotyledon anlagen and primordia by modulating epidermal cell shape and polarity.
RPK1 causes salt sensitivity by increasing Na+ ion flux into cells under salt stress
Title: Overexpression of the receptor-like protein kinase genes AtRPK1 and OsRPK1 reduces the salt tolerance of Arabidopsis thaliana.
Fine mapping by local association analysis identified RECEPTOR-LIKE PROTEIN KINASE1 (RPK1), an abscisic acid-related receptor, as the most likely gene underlying REG-1.
Title: Combining linkage and association mapping identifies RECEPTOR-LIKE PROTEIN KINASE1 as an essential Arabidopsis shoot regeneration gene.
Sucrose-induced receptor kinase (RPK1) regulates a plasma membrane aquaporin in Arabidopsis.
Title: Sucrose-induced receptor kinase SIRK1 regulates a plasma membrane aquaporin in Arabidopsis.
RPK1 plays different roles at different stages of development. The effect of ABA and ABA-inducible RPK1 on leaf senescence is dependent on the age of the plant.
Title: Age-dependent action of an ABA-inducible receptor kinase, RPK1, as a positive regulator of senescence in Arabidopsis leaves.
RPK1 overproduction controls reactive oxygen species homeostasis and enhances both water and oxidative stress tolerance in Arabidopsis
Title: Overproduction of the membrane-bound receptor-like protein kinase 1, RPK1, enhances abiotic stress tolerance in Arabidopsis.
RPK1 and TOAD2 are primarily required to maintain central domain protoderm cell fate and that the loss of this key embryonic cell type in mutant embryos results indefects in other regions of embryo including the failure to initiate cotyledon primordia.
Title: Two receptor-like kinases required together for the establishment of Arabidopsis cotyledon primordia.

Submit: New GeneRIF Correction See all GeneRIFs (11)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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NM_105594.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables identical protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables kinase activity	ISS Inferred from Sequence or Structural Similarity more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein kinase activity	IDA Inferred from Direct Assay more info	PubMed
enables protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within abscisic acid-activated signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in embryonic meristem development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in longitudinal axis specification	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in radial axis specification	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to abscisic acid	IEP Inferred from Expression Pattern more info	PubMed
involved_in response to cold	IEP Inferred from Expression Pattern more info	PubMed
involved_in response to salt stress	IEP Inferred from Expression Pattern more info	PubMed
involved_in response to water deprivation	IEP Inferred from Expression Pattern more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	ISM Inferred from Sequence Model more info
located_in peroxisome	HDA more info	PubMed
located_in plasma membrane	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: receptor-like protein kinase 1

NP_177087.1

receptor-like protein kinase 1 (RPK1); CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Leucine-rich repeat-containing N-terminal domain, type 2 (InterPro:IPR013210), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: receptor-like protein kinase 2 (TAIR:AT3G02130.1); Has 135462 Blast hits to 127527 proteins in 4655 species: Archae - 122; Bacteria - 14490; Metazoa - 45605; Fungi - 10969; Plants - 44066; Viruses - 629; Other Eukaryotes - 19581 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003070.9 Reference assembly

Range

26040689..26042741 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_105594.3 → NP_177087.1 receptor-like protein kinase 1 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_177087.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9LQ97, Q9ZRF9

UniProtKB/TrEMBL

A0A178WLF7, A0A5S9WSW1

Conserved Domains (2) summary

pfam00069
Location:267 → 530

Pkinase; Protein kinase domain

cl21453
Location:267 → 535

PKc_like; Protein Kinases, catalytic domain