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    GMP synthase (glutamine-hydrolyzing), putative / glutamine amidotransferase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842670, updated on 18-Sep-2024

    Summary

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    Official Full Name
    GMP synthase (glutamine-hydrolyzing), putative / glutamine amidotransferase
    Primary source
    TAIR:AT1G63660
    Locus tag
    AT1G63660
    See related
    Araport:AT1G63660
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F24D7.15; F24D7_15
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    6
    Sequence:
    Chromosome: 1; NC_003070.9 (23603791..23607275, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene P-loop nucleoside triphosphate hydrolases superfamily protein with CH (Calponin Homology) domain-containing protein Neighboring gene basic helix-loop-helix (bHLH) DNA-binding superfamily protein Neighboring gene hypothetical protein (DUF3741) Neighboring gene ALBINO OR PALE-GREEN 13

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article
    2. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article
    3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_105043.4
    NM_202352.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables GMP synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in GMP biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 

    General protein information

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    Preferred Names
    GMP synthase (glutamine-hydrolyzing), putative / glutamine amidotransferase
    NP_176553.1
    • GMP synthase (glutamine-hydrolyzing), putative / glutamine amidotransferase, putative; FUNCTIONS IN: asparagine synthase (glutamine-hydrolyzing) activity, catalytic activity, GMP synthase (glutamine-hydrolyzing) activity, ATP binding; INVOLVED IN: in 7 processes; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Glutamine amidotransferase class-I, C-terminal (InterPro:IPR000991), Glutamine amidotransferase superfamily (InterPro:IPR011702), GMP synthase, N-terminal (InterPro:IPR004739), GMP synthase, C-terminal (InterPro:IPR001674), Rossmann-like alpha/beta/alpha sandwich fold (InterPro:IPR014729), Glutamine amidotransferase type 1 (InterPro:IPR017926), Asparagine synthase (InterPro:IPR001962), Anthranilate synthase component II/delta crystallin (InterPro:IPR006220); Has 20887 Blast hits to 20751 proteins in 2946 species: Archae - 738; Bacteria - 12164; Metazoa - 273; Fungi - 298; Plants - 185; Viruses - 0; Other Eukaryotes - 7229 (source: NCBI BLink).
    NP_974081.1
    • GMP synthase (glutamine-hydrolyzing), putative / glutamine amidotransferase, putative; FUNCTIONS IN: asparagine synthase (glutamine-hydrolyzing) activity, GMP synthase (glutamine-hydrolyzing) activity, catalytic activity, ATP binding; INVOLVED IN: GMP biosynthetic process, glutamine metabolic process, biosynthetic process, asparagine biosynthetic process; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Rossmann-like alpha/beta/alpha sandwich fold (InterPro:IPR014729), Glutamine amidotransferase class-I, C-terminal (InterPro:IPR000991), Glutamine amidotransferase superfamily (InterPro:IPR011702), GMP synthase, N-terminal (InterPro:IPR004739), Glutamine amidotransferase type 1 (InterPro:IPR017926), Asparagine synthase (InterPro:IPR001962), Anthranilate synthase component II/delta crystallin (InterPro:IPR006220); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      23603791..23607275 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105043.4 → NP_176553.1  GMP synthase (glutamine-hydrolyzing), putative / glutamine amidotransferase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_176553.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2E2Y0, Q84WB8, Q9CAD1
      Conserved Domains (3) summary
      cd01742
      Location:11 → 197
      GATase1_GMP_Synthase; Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase
      PLN02347
      Location:1 → 534
      PLN02347; GMP synthetase
      cd01997
      Location:229 → 533
      GMP_synthase_C; The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched ...

    2. NM_202352.1 → NP_974081.1  GMP synthase (glutamine-hydrolyzing), putative / glutamine amidotransferase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974081.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2E2Y0, F4I3P5, Q84WB8
      Conserved Domains (3) summary
      TIGR00888
      Location:11 → 202
      guaA_Nterm; GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit
      cd01742
      Location:11 → 197
      GATase1_GMP_Synthase; Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase
      cd01997
      Location:229 → 434
      GMP_synthase_C; The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched ...
    Nucleotide Protein
    Heading Accession and Version

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