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    MPK11 MAP kinase 11 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839523, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MPK11
    Official Full Name
    MAP kinase 11
    Primary source
    TAIR:AT1G01560
    Locus tag
    AT1G01560
    See related
    Araport:AT1G01560
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATMPK11; F22L4.10; F22L4_10; MAP kinase 11
    Summary
    member of MAP Kinase
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    Genomic context

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    See MPK11 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    5
    Sequence:
    Chromosome: 1; NC_003070.9 (202103..204440)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Protein kinase superfamily protein Neighboring gene BPS1-like protein (DUF793) Neighboring gene transferring glycosyl group transferase (DUF604) Neighboring gene ferric reduction oxidase 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Activation of the Arabidopsis thaliana mitogen-activated protein kinase MPK11 by the flagellin-derived elicitor peptide, flg22. Bethke G, et al. Mol Plant Microbe Interact, 2012 Apr. PMID 22204645
    2. Bacterial AvrRpt2-Like Cysteine Proteases Block Activation of the Arabidopsis Mitogen-Activated Protein Kinases, MPK4 and MPK11. Eschen-Lippold L, et al. Plant Physiol, 2016 Jul. PMID 27208280, Free PMC Article
    3. AtMPK4 is required for male-specific meiotic cytokinesis in Arabidopsis. Zeng Q, et al. Plant J, 2011 Sep. PMID 21575092
    4. Mapping out the roles of MAP kinases in plant defense. Innes RW. Trends Plant Sci, 2001 Sep. PMID 11544109
    5. Comprehensive analysis of protein-protein interactions between Arabidopsis MAPKs and MAPK kinases helps define potential MAPK signalling modules. Lee JS, et al. Plant Signal Behav, 2008 Dec. PMID 19513235, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. AvrRpt2 specifically blocks the flagellin-induced activation of MPK11.
      Title: Bacterial AvrRpt2-Like Cysteine Proteases Block Activation of the Arabidopsis Mitogen-Activated Protein Kinases, MPK4 and MPK11.
    2. findings show that MPK11 activity can be increased through flg22 elicitation
      Title: Activation of the Arabidopsis thaliana mitogen-activated protein kinase MPK11 by the flagellin-derived elicitor peptide, flg22.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001123738.2
    NM_001331282.1
    NM_100038.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables MAP kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables MAP kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within response to abscisic acid IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within signal transduction IC
    Inferred by Curator
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol HDA PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    MAP kinase 11
    NP_001117210.1
    • MAP kinase 11 (MPK11); FUNCTIONS IN: MAP kinase activity, kinase activity; INVOLVED IN: signal transduction, response to abscisic acid stimulus; LOCATED IN: cellular_component unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), JNK MAP kinase (InterPro:IPR008351), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase-like domain (InterPro:IPR011009), MAP kinase, conserved site (InterPro:IPR003527), Protein kinase, catalytic domain (InterPro:IPR000719), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635); BEST Arabidopsis thaliana protein match is: MAP kinase 4 (TAIR:AT4G01370.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_563631.2
    • MAP kinase 11 (MPK11); FUNCTIONS IN: MAP kinase activity, kinase activity; INVOLVED IN: signal transduction, response to abscisic acid stimulus; LOCATED IN: cellular_component unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase-like domain (InterPro:IPR011009), MAP kinase, conserved site (InterPro:IPR003527), Protein kinase, catalytic domain (InterPro:IPR000719), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635); BEST Arabidopsis thaliana protein match is: MAP kinase 4 (TAIR:AT4G01370.1); Has 120594 Blast hits to 119420 proteins in 4621 species: Archae - 98; Bacteria - 12299; Metazoa - 46324; Fungi - 12052; Plants - 29649; Viruses - 464; Other Eukaryotes - 19708 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      202103..204440
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001331281.1 → NP_001322112.1  MAP kinase 11 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8ASZ4, A0A5S9S3I0

    2. NM_001123738.2 → NP_001117210.1  MAP kinase 11 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001117210.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B3H762, Q9LMM5
      UniProtKB/TrEMBL
      A0A178W1B0, A0A5S9S3I0
      Conserved Domains (1) summary
      cd07858
      Location:33 → 369
      STKc_TEY_MAPK; Catalytic domain of the Serine/Threonine Kinases, Plant TEY Mitogen-Activated Protein Kinases

    3. NM_100038.4 → NP_563631.2  MAP kinase 11 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_563631.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LMM5
      Conserved Domains (1) summary
      cl21453
      Location:33 → 256
      PKc_like; Protein Kinases, catalytic domain

    4. NM_001331282.1 → NP_001322113.1  MAP kinase 11 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LMM5
      Conserved Domains (1) summary
      cl21453
      Location:33 → 256
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LMM5.1

    Gene LinkOut

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